An oral DNA vaccine against infectious haematopoietic necrosis virus (IHNV) encapsulated in alginate microspheres induces dose-dependent immune responses and significant protection in rainbow trout (Oncorrhynchus mykiss)

Fish and Shellfish Immunology

Volumn 45, Issue 2, 2015, Pages 877-888

  Ballesteros, Natalia A ^a   Alonso, Marta ^b   Saint Jean, Sylvia Rodríguez ^a   Perez Prieto, Sara I ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b NEIKER and a Vaccine producing Commercial Company CZVSL   (Spain)

Author keywords

Alginate microencapsulation; IHNV; Infectious haematopoietic necrosis virus; Interferon regulatory factor 1A (IRF1A); Oral DNA vaccines; Rainbow trout

Indexed keywords

INFECTIOUS HEMATOPOIETIC NECROSIS VIRUS; ONCORHYNCHUS MYKISS;

ALGINIC ACID; DNA VACCINE; GLUCURONIC ACID; HEXURONIC ACID; MESSENGER RNA; MICROSPHERE; VIRUS ANTIBODY; VIRUS VACCINE;

ADAPTIVE IMMUNITY; ANIMAL; DOSE RESPONSE; FISH DISEASE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INFECTIOUS HEMATOPOIETIC NECROSIS VIRUS; INNATE IMMUNITY; KIDNEY; METABOLISM; ONCORHYNCHUS MYKISS; ORAL DRUG ADMINISTRATION; RHABDOVIRUS INFECTION; SPLEEN; VETERINARY; VIROLOGY; VIRUS LOAD;

ADAPTIVE IMMUNITY; ADMINISTRATION, ORAL; ALGINATES; ANIMALS; ANTIBODIES, VIRAL; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FISH DISEASES; GENE EXPRESSION REGULATION; GLUCURONIC ACID; HEXURONIC ACIDS; IMMUNITY, INNATE; INFECTIOUS HEMATOPOIETIC NECROSIS VIRUS; KIDNEY; MICROSPHERES; ONCORHYNCHUS MYKISS; RHABDOVIRIDAE INFECTIONS; RNA, MESSENGER; SPLEEN; VACCINES, DNA; VIRAL LOAD; VIRAL VACCINES;

EID: 84934952449     PISSN: 10504648     EISSN: 10959947     Source Type: Journal    
DOI: 10.1016/j.fsi.2015.05.045     Document Type: Article

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