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Volumn 43, Issue , 2015, Pages 146-150

Molecular simulation studies of hydrophobic gating in nanopores and ion channels

Author keywords

Channel; Gating; Membrane; Nanopore

Indexed keywords

ION CHANNEL; NICOTINIC RECEPTOR; POTASSIUM CHANNEL; TWIK 1 POTASSIUM CHANNEL; UNCLASSIFIED DRUG; CARRIER PROTEIN; KCNK1 PROTEIN, HUMAN; TANDEM PORE DOMAIN POTASSIUM CHANNEL; WATER;

EID: 84934924023     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20140256     Document Type: Article
Times cited : (24)

References (22)
  • 1
    • 0032084499 scopus 로고    scopus 로고
    • Molecular dynamics simulations of ion channels: How far have we gone and where are we heading?
    • CrossRef PubMed
    • Roux, B. (1998) Molecular dynamics simulations of ion channels: how far have we gone and where are we heading? Biophys. J. 74, 2744-2745 CrossRef PubMed
    • (1998) Biophys. J. , vol.74 , pp. 2744-2745
    • Roux, B.1
  • 2
    • 0035705881 scopus 로고    scopus 로고
    • Simulation approaches to ion channel structure-function relationships
    • CrossRef
    • Tieleman, D.P., Biggin, P.C., Smith, G.R. and Sansom, M.S.P. (2001) Simulation approaches to ion channel structure-function relationships. Quart. Rev. Biophys. 34, 473-561 CrossRef
    • (2001) Quart. Rev. Biophys. , vol.34 , pp. 473-561
    • Tieleman, D.P.1    Biggin, P.C.2    Smith, G.R.3    Sansom, M.S.P.4
  • 4
    • 4143116650 scopus 로고    scopus 로고
    • Computational studies of membrane channels
    • CrossRef PubMed
    • Roux, B. and Schulten, K. (2004) Computational studies of membrane channels. Structure 12, 1343-1351 CrossRef PubMed
    • (2004) Structure , vol.12 , pp. 1343-1351
    • Roux, B.1    Schulten, K.2
  • 5
    • 0035961071 scopus 로고    scopus 로고
    • A hydrophobic gating mechanism for nanopores
    • CrossRef
    • Beckstein, O., Biggin, P.C. and Sansom, M.S.P. (2001) A hydrophobic gating mechanism for nanopores. J. Phys. Chem. B 105, 12902-12905 CrossRef
    • (2001) J. Phys. Chem. B , vol.105 , pp. 12902-12905
    • Beckstein, O.1    Biggin, P.C.2    Sansom, M.S.P.3
  • 6
    • 0038472282 scopus 로고    scopus 로고
    • Liquid-vapor oscillations of water in hydrophobic nanopores
    • CrossRef
    • Beckstein, O. and Sansom, M.S.P. (2003) Liquid-vapor oscillations of water in hydrophobic nanopores. Proc. Nat. Acad. Sci. U.S.A. 100, 7063-7068 CrossRef
    • (2003) Proc. Nat. Acad. Sci. U.S.A. , vol.100 , pp. 7063-7068
    • Beckstein, O.1    Sansom, M.S.P.2
  • 7
    • 0041877629 scopus 로고    scopus 로고
    • Molecular dynamics investigation of water permeation through nanopores
    • CrossRef
    • Allen, R., Hansen, J.P. and Melchionna, S. (2003) Molecular dynamics investigation of water permeation through nanopores. J. Chem. Phys. 119, 3905-3919 CrossRef
    • (2003) J. Chem. Phys. , vol.119 , pp. 3905-3919
    • Allen, R.1    Hansen, J.P.2    Melchionna, S.3
  • 8
    • 0035829539 scopus 로고    scopus 로고
    • Water conduction through the hydrophobic channel of a carbon nanotube
    • CrossRef PubMed
    • Hummer, G., Rasaiah, J.C. and Noworyta, J.P. (2001) Water conduction through the hydrophobic channel of a carbon nanotube. Nature 414, 188-190 CrossRef PubMed
    • (2001) Nature , vol.414 , pp. 188-190
    • Hummer, G.1    Rasaiah, J.C.2    Noworyta, J.P.3
  • 9
    • 33748573642 scopus 로고    scopus 로고
    • The influence of geometry, surface character and flexibility on the permeation of ions and water through biological pores
    • CrossRef PubMed
    • Beckstein, O. and Sansom, M.S.P. (2004) The influence of geometry, surface character and flexibility on the permeation of ions and water through biological pores. Phys. Biol. 1, 42-52 CrossRef PubMed
    • (2004) Phys. Biol. , vol.1 , pp. 42-52
    • Beckstein, O.1    Sansom, M.S.P.2
  • 10
    • 8844228899 scopus 로고    scopus 로고
    • Not ions alone: Barriers to ion permeation in nanopores and channels
    • CrossRef PubMed
    • Beckstein, O., Tai, K. and Sansom, M.S.P. (2004) Not ions alone: barriers to ion permeation in nanopores and channels. J. Am. Chem. Soc. 126, 14694-14695 CrossRef PubMed
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 14694-14695
    • Beckstein, O.1    Tai, K.2    Sansom, M.S.P.3
  • 11
    • 83455222535 scopus 로고    scopus 로고
    • Electric-field-induced wetting and dewetting in single hydrophobic nanopores
    • CrossRef PubMed
    • Powell, M.R., Cleary, L., Davenport, M., Shea, K.J. and Siwy, Z.S. (2011) Electric-field-induced wetting and dewetting in single hydrophobic nanopores. Nat. Nanotechnol. 6, 798-802 CrossRef PubMed
    • (2011) Nat. Nanotechnol. , vol.6 , pp. 798-802
    • Powell, M.R.1    Cleary, L.2    Davenport, M.3    Shea, K.J.4    Siwy, Z.S.5
  • 12
    • 33745907550 scopus 로고    scopus 로고
    • A hydrophobic gate in an ion channel: The closed state of the nicotinic acetylcholine receptor
    • CrossRef PubMed
    • Beckstein, O. and Sansom, M.S.P. (2006) A hydrophobic gate in an ion channel: the closed state of the nicotinic acetylcholine receptor. Phys. Biol. 3, 147-159 CrossRef PubMed
    • (2006) Phys. Biol. , vol.3 , pp. 147-159
    • Beckstein, O.1    Sansom, M.S.P.2
  • 13
    • 43049122273 scopus 로고    scopus 로고
    • Water in nonpolar confinement: From nanotubes to proteins and beyond
    • CrossRef
    • Rasaiah, J.C., Garde, S. and Hummer, G. (2008) Water in nonpolar confinement: From nanotubes to proteins and beyond. Ann. Rev. Phys. Chem. 59, 713-740 CrossRef
    • (2008) Ann. Rev. Phys. Chem. , vol.59 , pp. 713-740
    • Rasaiah, J.C.1    Garde, S.2    Hummer, G.3
  • 14
    • 84864741408 scopus 로고    scopus 로고
    • Drying transition in the hydrophobic gate of the GLIC channel blocks ion conduction
    • CrossRef PubMed
    • Zhu, F.Q. and Hummer, G. (2012) Drying transition in the hydrophobic gate of the GLIC channel blocks ion conduction. Biophys. J. 103, 219-227 CrossRef PubMed
    • (2012) Biophys. J. , vol.103 , pp. 219-227
    • Zhu, F.Q.1    Hummer, G.2
  • 16
    • 84903954822 scopus 로고    scopus 로고
    • A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel
    • CrossRef PubMed
    • Aryal, P., Abd-Wahab, F., Sansom, M.S.P. and Tucker, S.J. (2014) A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel. Nat. Commun. 5, 4377 CrossRef PubMed
    • (2014) Nat. Commun. , vol.5 , pp. 4377
    • Aryal, P.1    Abd-Wahab, F.2    Sansom, M.S.P.3    Tucker, S.J.4
  • 17
    • 84919650170 scopus 로고    scopus 로고
    • Hydrophobic gating in ion channels
    • CrossRef PubMed
    • Aryal, P., Sansom, M.S.P. and Tucker, S.J. (2014) Hydrophobic gating in ion channels. J. Mol. Biol. 427, 121-130 CrossRef PubMed
    • (2014) J. Mol. Biol. , vol.427 , pp. 121-130
    • Aryal, P.1    Sansom, M.S.P.2    Tucker, S.J.3
  • 19
    • 44049102228 scopus 로고    scopus 로고
    • Outer membrane protein G: Engineering a quiet pore for biosensing
    • CrossRef PubMed
    • Chen, M., Khalid, S., Sansom, M.S.P. and Bayley, H. (2008) Outer membrane protein G: engineering a quiet pore for biosensing. Proc. Natl. Acad. Sci. U.S.A. 105, 6272-6277 CrossRef PubMed
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 6272-6277
    • Chen, M.1    Khalid, S.2    Sansom, M.S.P.3    Bayley, H.4
  • 20
    • 0035855827 scopus 로고    scopus 로고
    • Stochastic sensors inspired by biology
    • CrossRef PubMed
    • Bayley, H. and Cremer, P.S. (2001) Stochastic sensors inspired by biology. Nature 413, 226-230 CrossRef PubMed
    • (2001) Nature , vol.413 , pp. 226-230
    • Bayley, H.1    Cremer, P.S.2
  • 21
    • 84912573287 scopus 로고    scopus 로고
    • Designing a hydrophobic gate within biomimetic nanopores
    • PubMed
    • Trick, J.L., Wallace, E.J., Bayley, H. and Sansom, M.S.P. (2014) Designing a hydrophobic gate within biomimetic nanopores. ACS Nano 8, 11268-11279 PubMed
    • (2014) ACS Nano , vol.8 , pp. 11268-11279
    • Trick, J.L.1    Wallace, E.J.2    Bayley, H.3    Sansom, M.S.P.4
  • 22
    • 1842682281 scopus 로고    scopus 로고
    • Electric field-controlled water permeation coupled to ion transport through a nanopore
    • CrossRef PubMed
    • Dzubiella, J., Allen, R.J. and Hansen, J.P. (2004) Electric field-controlled water permeation coupled to ion transport through a nanopore. J. Chem. Phys. 120, 5001-5004 CrossRef PubMed
    • (2004) J. Chem. Phys. , vol.120 , pp. 5001-5004
    • Dzubiella, J.1    Allen, R.J.2    Hansen, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.