Structural and functional differences in the cingulate cortex relate to disease severity in anorexia nervosa

Journal of Psychiatry and Neuroscience

Volumn 40, Issue 4, 2015, Pages 269-279

  Bär, Karl Jürgen ^a   de la Cruz, Feliberto ^a   Berger, Sandy ^a   Schultz, Carl Christoph ^a   Wagner, Gerd ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANOREXIA NERVOSA; ARTICLE; BODY MASS; BOLD SIGNAL; CINGULATE GYRUS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CORTICAL THICKNESS (BRAIN); DEPRESSION; DISEASE SEVERITY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GRAY MATTER; HEMISPHERE; HUMAN; MALE; PAIN THRESHOLD; PARIETAL CORTEX; SCORING SYSTEM; THERMAL STIMULATION; VOXEL BASED MORPHOMETRY; BRAIN MAPPING; HEAT; IMAGE PROCESSING; NOCICEPTION; NUCLEAR MAGNETIC RESONANCE IMAGING; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSICAL STIMULATION; PHYSIOLOGY; PSYCHOLOGICAL RATING SCALE; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

ANOREXIA NERVOSA; BRAIN MAPPING; FEMALE; GRAY MATTER; GYRUS CINGULI; HOT TEMPERATURE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; ORGAN SIZE; PAIN PERCEPTION; PAIN THRESHOLD; PHYSICAL STIMULATION; PSYCHIATRIC STATUS RATING SCALES; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84934759471     PISSN: 11804882     EISSN: 14882434     Source Type: Journal    
DOI: 10.1503/jpn.140193     Document Type: Article

References (58)

1. Bruch H. Perceptual and conceptual disturbances in anorexia nervosa. Psychosom Med 1962;24:187-94.
2. van Kuyck K, Gerard N, Van Laere K, et al. Towards a neurocircuitry in anorexia nervosa: evidence from functional neuroimaging studies. J Psychiatr Res 2009;43:1133-45.
3. Delvenne V, Lotstra F, Goldman S, et al. Brain hypometabolism of glucose in anorexia nervosa: a PET scan study. Biol Psychiatry 1995;37:161-9.
4. Kojima S, Nagai N, Nakabeppu Y, et al. Comparison of regional cerebral blood flow in patients with anorexia nervosa before and after weight gain. Psychiatry Res 2005;140:251-8.
5. Uher R, Brammer MJ, Murphy T, et al. Recovery and chronicity in anorexia nervosa: brain activity associated with differential outcomes. Biol Psychiatry 2003;54:934-42.
6. Santel S, Baving L, Krauel K, et al. Hunger and satiety in anorexia nervosa: fMRI during cognitive processing of food pictures. Brain Res 2006;1114:138-48.
7. Friederich HC, Brooks S, Uher R, et al. Neural correlates of body dissatisfaction in anorexia nervosa. Neuropsychologia 2010;48:2878-85.
8. McFadden KL, Tregellas JR, Shott ME, et al. Reduced salience and default mode network activity in women with anorexia nervosa. J Psychiatry Neurosci 2014;39:178-88.
9. Takano A, Shiga T, Kitagawa N, et al. Abnormal neuronal network in anorexia nervosa studied with I-123-IMP SPECT. Psychiatry Res 2001;107:45-50.
10. Frank GK, Shott ME, Hagman JO, et al. Alterations in brain structures related to taste reward circuitry in ill and recovered anorexia nervosa and in bulimia nervosa. Am J Psychiatry 2013;170:1152-60.
11. Gaudio S, Quattrocchi CC. Neural basis of a multidimensional model of body image distortion in anorexia nervosa. Neurosci Biobehav Rev 2012;36:1839-47.
12. Strigo IA, Matthews SC, Simmons AN, et al. Altered insula activation during pain anticipation in individuals recovered from anorexia nervosa: evidence of interoceptive dysregulation. Int J Eat Disord 2013;46:23-33.
13. Craig AD. How do you feel-now? The anterior insula and human awareness. Nat Rev Neurosci 2009;10:59-70.
14. Craig AD. How do you feel? Interoception: the sense of the physiological condition of the body. Nat Rev Neurosci 2002;3:655-66.
15. Augustine JR. Circuitry and functional aspects of the insular lobe in primates including humans. Brain Res Brain Res Rev 1996; 22:229-44.
16. Nunn K, Frampton I, Gordon I, et al. The fault is not in her parents but in her insula - a neurobiological hypothesis of anorexia nervosa. Eur Eat Disord Rev 2008;16:355-60.
17. Bär KJ, Berger S, Schwier C, et al. Insular dysfunction and descending pain inhibition in anorexia nervosa. Acta Psychiatr Scand 2013;127:269-78.
18. de Zwaan M, Biener D, Bach M, et al. Pain sensitivity, alexithymia, and depression in patients with eating disorders: Are they related? J Psychosom Res 1996;41:65-70.
19. Bär KJ, Boettger S, Wagner G, et al. Changes of pain perception, autonomic function, and endocrine parameters during treatment of anorectic adolescents. J Am Acad Child Adolesc Psychiatry 2006;45:1068-76.
20. Wöckel L, Hummel T, Zepf FD, et al. Changed taste perception in patients with eating disorders. Z Kinder Jugendpsychiatr Psychother 2007;35:423-34.
21. Wager TD, Atlas LY, Lindquist MA, et al. An fMRI-based neurologic signature of physical pain. N Engl J Med 2013;368:1388-97.
22. Van den Eynde F, Suda M, Broadbent H, et al. Structural magnetic resonance imaging in eating disorders: a systematic review of voxel-based morphometry studies. Eur Eat Disord Rev 2012;20:94-105.
23. Joos A, Kloppel S, Hartmann A, et al. Voxel-based morphometry in eating disorders: correlation of psychopathology with grey matter volume. Psychiatry Res 2010;182:146-51.
24. Suchan B, Busch M, Schulte D, et al. Reduction of gray matter density in the extrastriate body area in women with anorexia nervosa. Behav Brain Res 2010;206:63-7.
25. Boghi A, Sterpone S, Sales S, et al. In vivo evidence of global and focal brain alterations in anorexia nervosa. Psychiatry Res 2011;192:154-9.
26. Brooks SJ, Barker GJ, O'Daly OG, et al. Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study. BMC Psychiatry 2011;11:179.
27. Mühlau M, Gaser C, Ilg R, et al. Gray matter decrease of the anterior cingulate cortex in anorexia nervosa. Am J Psychiatry 2007;164:1850-7.
28. Winkler AM, Kochunov P, Blangero J, et al. Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies. Neuroimage 2010;53:1135-46.
29. Wagner G, Schultz CC, Koch K, et al. Prefrontal cortical thickness in depressed patients with high-risk for suicidal behavior. J Psychiatr Res 2012;46:1449-55.
30. Bär KJ, Brehm S, Boettger MK, et al. Pain perception in major depression depends on pain modality. Pain 2005;117:97-103.
31. Bär KJ, Wagner G, Koschke M, et al. Increased prefrontal activation during pain perception in major depression. Biol Psychiatry 2007;62:1281-7.
32. Smith SM, Nichols TE. Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference. Neuroimage 2009;44:83-98.
33. Ward BD. Simultaneous inference for FMRI data. Milwaukee, Wisconsin: Medical College of Wisconsin; 2000.
34. Eggert LD, Sommer J, Jansen A, et al. Accuracy and reliability of automated gray matter segmentation pathways on real and simulated structural magnetic resonance images of the human brain. PLoS ONE 2012;7:e45081.
35. Fischl B, Dale AM. Measuring the thickness of the human cerebral cortex from magnetic resonance images. Proc Natl Acad Sci U S A 2000;97:11050-5.
36. Lou HC, Luber B, Crupain M, et al. Parietal cortex and representation of the mental Self. Proc Natl Acad Sci U S A 2004;101:6827-32.
37. Wagner G, Koch K, Schachtzabel C, et al. Self-referential processing influences functional activation during cognitive control: an fMRI study. Soc Cogn Affect Neurosci 2013;8:828-37.
38. Mohr HM, Zimmermann J, Roder C, et al. Separating two components of body image in anorexia nervosa using fMRI. Psychol Med 2010;40:1519-29.
39. Vocks S, Busch M, Gronemeyer D, et al. Neural correlates of viewing photographs of one's own body and another woman's body in anorexia and bulimia nervosa: an fMRI study. J Psychiatry Neurosci 2010;35:163-76.
40. Gaudio S, Nocchi F, Franchin T, et al. Gray matter decrease distribution in the early stages of Anorexia Nervosa restrictive type in adolescents. Psychiatry Res 2011;191:24-30.
41. McAdams CJ, Krawczyk DC. Who am I? How do I look? Neural differences in self-identity in anorexia nervosa. Soc Cogn Affect Neurosci 2014;9:12-21.
42. Brooks S, Prince A, Stahl D, et al. A systematic review and meta-analysis of cognitive bias to food stimuli in people with disordered eating behaviour. Clin Psychol Rev 2011;31:37-51.
43. Leech R, Braga R, Sharp DJ. Echoes of the brain within the posterior cingulate cortex. J Neurosci 2012;32:215-22.
44. Leech R, Kamourieh S, Beckmann CF, et al. Fractionating the default mode network: distinct contributions of the ventral and dorsal posterior cingulate cortex to cognitive control. J Neurosci 2011;31:3217-24.
45. Kingston K, Szmukler G, Andrewes D, et al. Neuropsychological and structural brain changes in anorexia nervosa before and after refeeding. Psychol Med 1996;26:15-28.
46. Lauer CJ, Gorzewski B, Gerlinghoff M, et al. Neuropsychological assessments before and after treatment in patients with anorexia nervosa and bulimia nervosa. J Psychiatr Res 1999;33:129-38.
47. Szmukler GI, Andrewes D, Kingston K, et al. Neuropsychological impairment in anorexia nervosa: before and after refeeding. J Clin Exp Neuropsychol 1992;14:347-52.
48. Grunwald M, Ettrich C, Assmann B, et al. Deficits in haptic perception and right parietal theta power changes in patients with anorexia nervosa before and after weight gain. Int J Eat Disord 2001;29:417-28.
49. Grunwald M, Ettrich C, Krause W, et al. Haptic perception in anorexia nervosa before and after weight gain. J Clin Exp Neuropsychol 2001;23:520-9.
50. Reed CL, Klatzky RL, Halgren E. What vs. where in touch: an fMRI study. Neuroimage 2005;25:718-26.
51. Cowdrey FA, Filippini N, Park RJ, et al. Increased resting state functional connectivity in the default mode network in recovered anorexia nervosa. Hum Brain Mapp 2014;35:483-91.
52. Matsumoto R, Kitabayashi Y, Narumoto J, et al. Regional cerebral blood flow changes associated with interoceptive awareness in the recovery process of anorexia nervosa. Prog Neuropsychopharmacol Biol Psychiatry 2006;30:1265-70.
53. Derbyshire SW, Jones AK, Creed F, et al. Cerebral responses to noxious thermal stimulation in chronic low back pain patients and normal controls. Neuroimage 2002;16:158-68.
54. Vogt BA, Berger GR, Derbyshire SW. Structural and functional dichotomy of human midcingulate cortex. Eur J Neurosci 2003;18:3134-44.
55. Beissner F, Meissner K, Bar KJ, et al. The autonomic brain: an activation likelihood estimation meta-analysis for central processing of autonomic function. J Neurosci 2013;33:10503-11.
56. Wagner A, Greer P, Bailer UF, et al. Normal brain tissue volumes after long-term recovery in anorexia and bulimia nervosa. Biol Psychiatry 2006;59:291-3.
57. Strober M, Freeman R, Lampert C, et al. Controlled family study of anorexia nervosa and bulimia nervosa: evidence of shared liability and transmission of partial syndromes. Am J Psychiatry 2000; 157:393-401.
58. Klump KL, Miller KB, Keel PK, et al. Genetic and environmental influences on anorexia nervosa syndromes in a population-based twin sample. Psychol Med 2001;31:737-40.