Analysis of drug interactions

Methods in Molecular Biology

Volumn 731, Issue , 2011, Pages 421-434

  Bijnsdorp, Irene V ^a   Giovannetti, Elisa ^a   Peters, Godefridus J ^a  

^a NONE

Author keywords

Antagonism; Calcusyn; Combination study; Drug cytotoxicity; Synergism

Indexed keywords

ERLOTINIB; PEMETREXED;

ARTICLE; CELL SUBPOPULATION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG COMBINATION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG INTERACTION; DRUG POTENTIATION; DRUG RESISTANCE; DRUG SCREENING; GROWTH INHIBITION; IMMUNOPATHOLOGY; PRIORITY JOURNAL; THERAPY EFFECT; VIRUS INFECTION; COMPUTER PROGRAM;

DRUG COMBINATIONS; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; SOFTWARE;

EID: 84934441904     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-80-5_34     Document Type: Article

References (13)

1. Peters, G.J., van der Wilt, C.L., van Moorsel, C.J., Kroep, J.R., Bergman, A.M. and Ackland, S.P. (2000) Basis for effective combination cancer chemotherapy with antimetabolites. Pharmacol. Ther. 87, 227-53.
2. Keepers, Y.P., Pizao, P.E., Peters, G.J., van Ark-Otte, J., Winograd, B. and Pinedo, H.M. (1991) Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing. Eur. J. Cancer. 27, 897-900.
3. Cree, I.A. and Kurbacher, C.M. (1999) ATP-based tumor chemosensitivity testing: assisting new agent development. Anticancer Drugs. 10, 431-5.
4. Berenbaum, M.C. (1989) What is synergy? (1989) Pharmacol. Rev. 41, 93-141.
5. Webb, J.L. (1963) Effect of more than one inhibitor. In Enzymes and Metabolic Inhibitors. New York: Academic Press. pp. 66-79.
6. Greco, W.R., Bravo, G., and Parsons, J.C. (1995) The search for synergy: a critical review from a response surface perspective. Pharmacol. Rev. 47, 331-385.
7. Kanzawa, F. and Saijo, N. (1997) In vitro interaction between gemcitabine and other antican-cer drugs using a novel three-dimensional model. Semin. Oncol. 24,:S7-8-S7-16.
8. Chou, T.C. and Talalay, P. (1984) Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul. 22, 27-55.
9. Chou, T.C. (2010) Drug combination studies and their synergy quantifcation using the Chou-Talalay method. Cancer Res. 70, 440-6.
10. Elion, G.B., Singer, S. and Hitchings G.H. (1954) Antagonists of nucleic acid derivatives: Part VIII. Synergism in combinations of biochemically related antimetabolites. J. Biol. Chem. 208, 477-488.
11. Steel, G.G. and Peckham, M.J. (1979) Exploitable mechanisms in combined radiotherapy-chemotherapy: the concept of additiv-ity. Int. J. Radiat. Oncol. Biol. Phys. 5, 85-91.
12. Padrón, J.M., van Moorsel, C.J., Bergman, A.M., Smitskamp-Wilms, E., van der Wilt, C.L. and Peters, G.J. (1999) Selective cell kill of the combination of gemcitabine and cispla-tin in multilayered postconfuent tumor cell cultures. Anticancer Drugs 10, 445-52.
13. Giovannetti, E., Lemos, C., Tekle, C., Smid, K., Nannizzi, S., Rodriguez, J.A., Ricciardi, S., Danesi, R., Giaccone, G. and Peters, G.J. (2008) Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells. Mol. Pharmacol. 73, 1290-300.