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Volumn 614, Issue , 2008, Pages 157-164

Activity of drug efflux transporters in tumor cells under hypoxic conditions

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCOPROTEIN P; LACTOSE; MULTIDRUG RESISTANCE PROTEIN 1;

EID: 84934439836     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-74911-2_19     Document Type: Conference Paper
Times cited : (16)

References (14)
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    • Schinkel, A.H.1    Jonker, J.W.2
  • 3
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    • Strategies for reversing drug resistance
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  • 4
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    • Multidrug resistance in androgen-independent growing rat prostate carcinoma cells is mediated by P-glycoprotein
    • M.J. Siegsmund, C. Kreukler, A. Steidler, T. Nebe, K.U. Kohrmann, and P. Alken. Multidrug resistance in androgen-independent growing rat prostate carcinoma cells is mediated by P-glycoprotein. Urol. Res. 25, 35-41 (1997).
    • (1997) Urol. Res , vol.25 , pp. 35-41
    • Siegsmund, M.J.1    Kreukler, C.2    Steidler, A.3    Nebe, T.4    Kohrmann, K.U.5    Alken, P.6
  • 5
    • 0024408986 scopus 로고
    • Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
    • P. Vaupel, F. Kallinowski, and P. Okunieff. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res. 49, 6449-6465 (1989).
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    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 6
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    • Tumor hypoxia: Definitions and current clinical, biological, and molecular aspects
    • M. Höckel and P. Vaupel. Tumor hypoxia: definitions and current clinical, biological, and molecular aspects. J. Natl. Cancer Inst. 93, 266-276 (2001).
    • (2001) J. Natl. Cancer Inst , vol.93 , pp. 266-276
    • Höckel, M.1    Vaupel, P.2
  • 7
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    • Cytokines alter the expression and activity of the multidrug resistance transporters in human hepatoma cell lines; analysis using RT-PCR and cDNA microarrays
    • G. Lee and M. Piquette-Miller. Cytokines alter the expression and activity of the multidrug resistance transporters in human hepatoma cell lines; analysis using RT-PCR and cDNA microarrays. J. Pharm. Sci. 92, 2152-2163 (2003).
    • (2003) J. Pharm. Sci , vol.92 , pp. 2152-2163
    • Lee, G.1    Piquette-Miller, M.2
  • 8
    • 0034664960 scopus 로고    scopus 로고
    • A new phosphospecific cell-based ELISA for p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein
    • H.H. Versteeg, E. Nijhuis, G.R. van den Brink, M. Evertzen, G.N. Pynaert, S.J. van Deventer, P.J. Coffer, and M.P. Peppelenbosch. A new phosphospecific cell-based ELISA for p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein. Biochem. J. 350, 717-722 (2000).
    • (2000) Biochem. J , vol.350 , pp. 717-722
    • Versteeg, H.H.1    Nijhuis, E.2    van den Brink, G.R.3    Evertzen, M.4    Pynaert, G.N.5    van Deventer, S.J.6    Coffer, P.J.7    Peppelenbosch, M.P.8
  • 9
    • 33646428345 scopus 로고    scopus 로고
    • Impact of extracellular acidity on the activity of p-glycoprotein and the cytotoxicity of chemotherapeutic drugs
    • O. Thews, B. Gassner, D.K. Kelleher, G. Schwerdt, and M. Gekle. Impact of extracellular acidity on the activity of p-glycoprotein and the cytotoxicity of chemotherapeutic drugs. Neoplasia 8, 143-152 (2006).
    • (2006) Neoplasia , vol.8 , pp. 143-152
    • Thews, O.1    Gassner, B.2    Kelleher, D.K.3    Schwerdt, G.4    Gekle, M.5
  • 10
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    • Intracellular acidosis in murine fibrosarcomas coincides with ATP depletion, hypoxia, and high levels of lactate and total Pi
    • P. Vaupel, C. Schaefer, and P. Okunieff. Intracellular acidosis in murine fibrosarcomas coincides with ATP depletion, hypoxia, and high levels of lactate and total Pi. NMR Biomed. 7, 128-136 (1994).
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    • Vaupel, P.1    Schaefer, C.2    Okunieff, P.3
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    • Inhibition of glycolysis in cancer cells: A novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia
    • R.H. Xu, H. Pelicano, Y. Zhou, J.S. Carew, L. Feng, K.N. Bhalla, M.J. Keating, and P. Huang. Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. Cancer Res. 65, 613-621 (2005).
    • (2005) Cancer Res , vol.65 , pp. 613-621
    • Xu, R.H.1    Pelicano, H.2    Zhou, Y.3    Carew, J.S.4    Feng, L.5    Bhalla, K.N.6    Keating, M.J.7    Huang, P.8
  • 12
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    • Effects of hypoxia on drug resistance phenotype and genotype in human glioma cell lines
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    • Liang, B.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.