Molecular targeted viral nanoparticles as tools for imaging cancer

Methods in Molecular Biology

Volumn 1108, Issue , 2014, Pages 211-230

  Cho, Choi Fong ^a   Shukla, Sourabh ^b,c,d   Simpson, Emily J ^e   Steinmetz, Nicole F ^b,c,d   Luyt, Leonard G ^e   Lewis, John D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b Case Western Reserve University   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Case Western Reserve University   (United States)

^e UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Bionanomaterials; Chemical conjugation; Click chemistry; Cowpea mosaic virus (CPMV); CPMV based viral nanoparticles; Molecular imaging agents; Peptide based affinity probes; Tumor homing nanoparticles

Indexed keywords

FLUORESCENT DYE; MACROGOL; NANOPARTICLE; PEPTIDE; UNCLASSIFIED DRUG; VIRAL NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCOMPATIBILITY; CLICK CHEMISTRY; CONJUGATION; CONTROLLED STUDY; COWPEA MOSAIC VIRUS; EMBRYO; IMAGING; IN VIVO STUDY; MOSAIC VIRUS; NONHUMAN; PRIORITY JOURNAL; TUMOR XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; CHICK EMBRYO; CLICK CHEMISTRY; FLUORESCENT DYES; HUMANS; MOLECULAR IMAGING; NANOPARTICLES; NEOPLASMS; PEPTIDES; VIRUSES;

EID: 84934437876     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-751-8_16     Document Type: Article

References (26)

1. Lewis JD, Destito G, Zijlstra A, Gonzalez MJ, Quigley JP, Manchester M, Stuhlmann H (2006) Viral nanoparticles as tools for intravital vascular imaging. Nat Med 12:354-360
2. Aina OH, Liu R, Sutcliffe JL, Marik J, Pan C-X, Lam KS (2007) From combinatorial chemistry to cancer-targeting peptides. Mol Pharm 4:631-651
3. Cho CF, Ablack A, Leong HS, Zijlstra A, Lewis J (2011) Evaluation of nanoparticle uptake in tumors in real time using intravital imaging. J Vis Exp 52:e2808
4. Cho CF, Amadei GA, Breadner D, Luyt LG, Lewis J (2012) The discovery of novel integrin ligands from combinatorial libraries using a multiplex "beads on a bead" approach. Nano Lett 12:5957-65
5. Steinmetz NF, Cho CF, Ablack A, Lewis JD, Manchester M (2011) Cowpea mosaic virus nanoparticles target surface vimentin on cancer cells. Nanomedicine (Lond) 6:351-364
6. Farokhzad OC, Langer R (2009) Impact of nanotechnology on drug delivery. ACS Nano 3:16-20
7. Leong HS, Steinmetz NF, Ablack A, Destito G, Zijlstra A, Stuhlmann H, Manchester M, Lewis JD (2010) Intravital imaging of embryonic and tumor neovasculature using viral nanoparticles. Nat Protoc 5:1406-1417
8. Steinmetz NF, Ablack AL, Hickey JL, Ablack J, Manocha B, Mymryk JS, Luyt LG, Lewis JD (2011) Intravital imaging of human prostate cancer using viral nanoparticles targeted to gastrin-releasing peptide receptors. Small 7:1664-1672
9. Chatterji A, Ochoa WF, Paine M, Ratna BR, Johnson JE, Lin T (2004) New addresses on an addressable virus nanoblock; uniquely reactive Lys residues on cowpea mosaic virus. Chem Biol 11:855-863
10. Brunel FM, Lewis JD, Destito G, Steinmetz NF, Manchester M, Stuhlmann H, Dawson PE (2010) Hydrazone ligation strategy to assemble multifunctional viral nanoparticles for cell imaging and tumor targeting. Nano Lett 10:1093-1097
11. Singh P, Prasuhn D, Yeh RM, Destito G, Rae CS, Osborn K, Finn MG, Manchester M (2007) Bio-distribution, toxicity and pathology of cowpea mosaic virus nanoparticles in vivo. J Control Release 120:41-50
12. Medintz IL, Sapsford KE, Konnert JH, Chatterji A, Lin T, Johnson JE, Mattoussi H (2005) Decoration of discretely immobilized cowpea mosaic virus with luminescent quantum dots. Langmuir 21(12):5501-5510
13. Sapsford KE, Soto CM, Blum AS, Chatterji A, Lin T, Johnson JE, Ligler FS, Ratna BR (2006) A cowpea mosaic virus nanoscaffold for multiplexed antibody conjugation: application as an immunoassay tracer. Biosens Bioelectron 21(8):1668-1673
14. Destito G, Yeh R, Rae CS, Finn MG, Manchester M (2007) Folic acid-mediated targeting of cowpea mosaic virus particles to tumor cells. Chem Biol 14:1152-1162
15. Steinmetz NF, Manchester M (2009) PEGylated viral nanoparticles for biomedicine: the impact of PEG chain length on VNP cell interactions in vitro and ex vivo. Biomacromolecules 10: 784-792
16. Kolb HC, Finn MG, Sharpless KB (2001) Click chemistry: diverse chemical function from a few good reactions. Angew Chem Int Ed Engl 40(11):2004-2021
17. Li ZJ, Cho CH (2012) Peptides as targeting probes against tumor vasculature for diagnosis and drug delivery. J Transl Med 10 (Suppl 1):1
18. Neveu C, Lefranc B, Tasseau O, Do-Rego JC, Bourmaud A, Chan P, Bauchat P, Le Marec O, Chuquet J, Guilhaudis L, Boutin JA, Segalas-Milazzo I, Costentin J, Vaudry H, Baudy-Floc'h M, Vaudry D, Leprince J (2012) Rational design of a low molecular weight, stable, potent, and long-lasting GPR103 aza-beta3- pseudopeptide agonist. J Med Chem 55(17):7516-7524
19. Auzzas L, Zanardi F, Battistini L, Burreddu P, Carta P, Rassu G, Curti C, Casiraghi G (2010) Targeting alphavbeta3 integrin: design and applications of mono-and multifunctional RGD-based peptides and semipeptides. Curr Med Chem 17(13):1255-1299
20. Devlin JJ, Panganiban LC, Devlin PE (1990) Random peptide libraries: a source of specifi c protein binding molecules. Science 249(4967):404-406
21. Lam KS, Salmon SE, Hersh EM, Hruby VJ, Kazmierski WM, Knapp RJ (1991) A new type of synthetic peptide library for identifying ligand-binding activity. Nature 354:82-84
22. Cretu A, Fotos JS, Little BW, Galileo DS (2005) Human and rat glioma growth, invasion, and vascularization in a novel chick embryo brain tumor model. Clin Exp Metastasis 22(3):225-236
23. Zijlstra A, Lewis J, Degryse B, Stuhlmann H, Quigley JP (2008) The inhibition of tumor cell intravasation and subsequent metastasis via regulation of in vivo tumor cell motility by the tetraspanin CD151. Cancer Cell 13(3):221-234
24. Chan WC, White PD (2000) Fmoc solid phase peptide synthesis: a practical approach. Oxford University Press, New York, p 288
25. Leong HS, Chambers AF, Lewis JD (2012) Assessing cancer cell migration and metastatic growth in vivo in the chick embryo using fl uorescence intravital imaging. Methods Mol Biol 872:1-14
26. Kaiser E, Colescott RL, Bossinger CD, Cook PI (1970) Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides. Anal Biochem 34(2):595-598