Real-time bioluminescence imaging of viral pathogenesis

Methods in Molecular Biology

Volumn 574, Issue , 2009, Pages 125-135

  Luker, Kathryn E ^a   Luker, Gary D ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

herpes simplex virus; Luciferase; mouse model; optical imaging; vaccinia

Indexed keywords

EID: 84934437720     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60327-321-3_11     Document Type: Article

References (13)

1. Luker, K., Hutchens, M., Schultz, T., Pekosz, A., and Luker, G. (2005) Bioluminescence imaging of vaccinia virus: effects of interferon on viral replication and spread. Virology 341, 284-300.
2. Hutchens, M., Luker, K., Sottile, P., Sonstein, J., Lukacs, N., Nunez, G., Curtis, J., and Luker, G. (2008) TLR3 increases disease morbidity and mortality from vaccinia infection. J Immunol 180, 483-491.
3. Cook, S., and Griffin, D. (2003) Luciferase imaging of a neurotropic viral infection in intact animals. J Virol 77, 5333-5338.
4. Pierson, T., Diamond, M., Ahmed, A., Valentine, L., Davis, C., Samuel, M., Hanna, S., Puffer, B., and Doms, R. (2005) An infectious West Nile virus that expresses a GFP reporter gene. Virology 334, 28-40.
5. Zhao, H., Doyle, T., Coquoz, O., Kalish, F., Rice, B., and Contag, C. (2005) Emission spectra of bioluminescent reporters and interaction with mammalian tissue determine the sensitivity of detection in vivo. J Biomed Optics 10, 41210.
6. Bhaumik, S., and Gambhir, S. (2002) Optical imaging of Renilla luciferase reporter gene expression in living mice. Proc Natl Acad Sci USA 99, 377-382.
7. Tannous, B., Kim, D., Fernandez, J., Weissleder, R., and Breakefield, X. (2005) Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol Ther 11, 435-443.
8. Loening, A., Wu, A., and Gambhir, S. (2007) Red-shifted Renilla reniformis luciferase variants for imaging in living subjects. Nat Methods 4, 641-643.
9. Luker, G., Bardill, J., Prior, J., Pica, C., Piwnica-Worms, D., and Leib, D. (2002) Noninvasive bioluminescence imaging of herpes simplex virus type 1 infection and therapy in living mice. J Virol 76, 12149-12161.
10. Saxena, M., Aton, F., Hildebolt, C., Prior, J., Abraham, U., Piwnica-Worms, D., and Herzog, E. (2007) Bioluminescence imaging of period1 gene expression in utero. Mol Imaging 6, 68-72.
11. Zhao, H., Doyle, T., Wong, R., Cao, Y., Stevenson, D., Piwnica-Worms, D., and Contag, C. (2004) Characterization of coelenterazine analogs for measurements of Renilla luciferase activity in live cells and living animals. Mol Imaging 3, 43-54.
12. Pichler, A., Prior, J., and Piwnica-Worms, D. (2004) Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine. Proc Natl Acad Sci USA 101, 1702-1707.
13. Paroo, Z., Bollinger, R., Braasch, D., Richer, E., Corey, D., Antich, P., and Mason, R. (2004) Validating bioluminescence imaging as a high-throughput, quantitative modality for assessing tumor burden. Mol imaging 3, 117-124.