Single-cell nanotoxicity assays of superparamagnetic iron oxide nanoparticles

Methods in Molecular Biology

Volumn 926, Issue , 2012, Pages 69-85

  Eustaquio, Trisha ^a   Leary, James F ^b  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Apoptosis; Cytotoxicity; Flow cytometry; LEAP; Nanotoxicity; Necrosis; Scanning image cytometry; Single cell; SPIONs; Superparamagnetic iron oxide nanoparticles

Indexed keywords

SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL COMMUNICATION; CELL CYCLE; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SUBPOPULATION; CELL SUSPENSION; CELL VIABILITY; CYTOTOXICITY; DNA DAMAGE; FLOW CYTOMETRY; IMAGE CYTOMETRY; INTRACELLULAR SIGNALING; NANOTOXICITY; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 84934437627     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-2-1_5     Document Type: Article

References (31)

1. Haglund E, Seale-Goldsmith M-M, Leary JF (2009) Design of multifunctional nanomedical systems. Ann Biomed Eng 37:2048-2063
2. Corot C, Robert P, Idee J-M, Port M (2006) Recent advances in iron oxide nanocrystal technology for medical imaging. Adv Drug Deliv Rev 58:1471-1504
3. Ito A, Kuga Y, Honda H, Kikkawa H, Horiuchi A, Watanabe Y, Kobayashi T (2004) Magnetite nanoparticle-loaded anti-HER2 immunoliposomes for combination of antibody therapy with hyperthermia. Cancer Lett 212:167-175
4. Kim D, Lee S, Kim K, Kim K, Shim I, Lee M, Lee Y-K (2006) Surface-modi fied magnetite nanoparticles for hyperthermia: preparation, characterization, and cytotoxicity studies. Curr Appl Phys 6:e242-e246
5. Kumar CS, Leuschner C, Doomes EE, Henry L, Juban M, Hormes J (2004) Efficacy of lytic peptide-bound magnetite nanoparticles in destroying breast cancer cells. J Nanosci Nanotechnol 4:245-249
6. Zhang Y, Sun C, Kohler N, Zhang M (2004) Self-assembled coatings on individual monodisperse magnetite nanoparticles for efficient intracellular uptake. Biomed Microdev 6: 33-40
7. Zhang Y, Yang M, Portney NG, Cui G, Budak E, Ozbay M, Ozkan M, Ozkan CS (2008) Zeta potential: a surface electrical characteristic to probe the interaction of nanoparticles with normal and cancer human breast epithelial cells. Biomed Microdev 10:321-328
8. Berry CC, Wells S, Charles S, Aitchison G, Curtis AS (2004) Cell response to dextranderivatised iron oxide nanoparticles post internalisation. Biomaterials 25:5405-5413
9. Mondalek FG, Zhang YY, Kropp B, Kopke RD, Ge X, Jackson RL, Dormer KJ (2006) The permability of SPION over an arti ficial threelayer membrane is enhanced by external magnetic field. J Nanobiotechnol 4:4
10. Bomati-Miguel O, Morales MP, Tartaj P, Ruiz-Cabello J, Bonville P, Santos M, Zhao X, Veintemillas-Verdaguer S (2005) Fe-based nanoparticulate metallic alloys as contrast agents for magnetic resonance imaging. Biomaterials 26:5695-5703
11. Moller W, Takenaka S, Buske N, Felten K, Heyder J (2005) Relaxation offerromagnetic nanoparticles in macrophages: in vitro and in vivo studies. J Magn Magn Mater 293: 245-251
12. Yin H, Too HP, Chow GM (2005) The effects of particle size and surface coating on the cytotoxicity of nickel ferrite. Biomaterials 26:5818-5826
13. Boutry S, Brunin S, Mahieu I, Laurent S, VanderElst L, Muller RN (2008) Magnetic labeling of non-phagocytic adherent cells with iron oxide nanoparticles: a comprehensive study. Contrast Media Mol Imaging 3: 223-232
14. Geraldes CF, Laurent S (2009) Classi fication and basic properties of contrast agents for magnetic resonance imaging. Contrast Media Mol Imaging 4:1-23
15. Kustermann E, Himmelreich U, Kandal K, Geelen T, Ketkar A, Wiedermann D, Strecker C, Esser J, Arnhold S, Hoehn M (2008) Efficient stem cell labeling for MRI studies. Contrast Media Mol Imaging 3:27-37
16. Oberdorster G, Oberdorster E, Oberdorster J (2005) Nanotoxicology: an emerging discipline evolving from studies of ultra fine particles. Environ Health Perspect 113:823-839
17. Stone V, Johnston H, Schins RPF (2009) Development of in vitro systems for nanotoxicology: methodological considerations. Crit Rev Toxicol 39:613-626
18. van Engeland M, Nieland LJ, Ramaekers FC, Schutte B, Reutelingsperger CP (1998) Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 31:1-9
19. Waring MJ (1965) Complex formation between ethidium bromide and nucleic acids. J Mol Biol 13:269-282
20. Koller MR, Palsson BO, Eisfeld TM (2003) Method for inducing a response in one or more targeted cells. US Patent 6,642,018
21. Palsson BO, Koller MR, Eisfeld TM (2003) Method and apparatus for selectively targeting speci fic cells within a cell population. US Patent 6,514,722
22. Palsson BO, Koller MR, Eisfeld TM (2003) Method and apparatus for selectively targeting speci fic cells within a mixed cell population. US Patent 6,534,308
23. Clark IB, Hanania EG, Stevens J, Gallina M, Fieck A, Brandes R, Palsson BO, Koller MR (2006) Optoinjection for efficient targeted delivery of a broad range of compounds and macromolecules into diverse cell types. J Biomed Opt 11:014034
24. Hanania EG, Fieck A, Stevens J, Bodzin LJ, Palsson BO, Koller MR (2005) Automated in situ measurement of cell-speci fic antibody secretion and laser-mediated puri fication for rapid cloning of highly-secreting producers. Biotechnol Bioeng 91:872-876
25. Koller MR, Hanania EG, Stevens J, Eisfeld TM, Sasaki GC, Fieck A, Palsson BO (2004) High-throughput laser-mediated in situ cell puri fication with high purity and yield. Cytometry A 61:153-161
26. Rhodes K, Clark I, Zatcoff M, Eustaquio T, Hoyte KL, Koller MR (2007) Cellular laserfection. Methods Cell Biol 82:309-333
27. Abraham SD, Knapp DW, Cheng L, Snyder PW, Mittal SK, Bangari DS, Kinch MS, Wu L, Dhariwal J, Mohammed SI (2006) Expression of EphA2 and ephrin A-1 in carcinoma of the urinary bladder. Clin Cancer Res 12:353-360
28. Seale M-M (2009) Design of targeted nanoparticles for multifunctional nanomedical systems. Ph.D. Thesis, Purdue University, Biomedical Engineering
29. Arndt-Jovin DJ, Jovin TM (1977) Analysis and sorting of living cells according to deoxyribonucleic acid content. J Histochem Cytochem 25:585-589
30. Invitrogen (2010, Sept) Alexa Fluor ® 488 annexin V/Dead Cell Apoptosis Kit with Alexa ® Fluor 488 annexin V and PI for Flow Cytometry. http://probes.invitrogen.com/media/pis/mp13241.pdf, [June 20, 2012]
31. Gallop PM, Paz MA, Henson E, Latt SA (1984) Dynamic approaches to the delivery of reporter reagents into living cells. Biotechniques 3:32-36