Identification of essential genes as a strategy to select a SARS candidate vaccine using a SARS-CoV infectious cDNA

Advances in Experimental Medicine and Biology

Volumn 581, Issue , 2006, Pages 579-583

  Almazán, Fernando ^a   De Diego, Marta L ^a   Galán, Carmen ^a   Álvarez, Enrique ^a   Enjuanes, Luis ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84934436233     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-33012-9_105     Document Type: Conference Paper

References (7)

1. J. S. Peiris, S. T. Lai, L. L. Poon, et al., Coronavirus as a possible cause of severe acute respiratory syndrome, Lancet 361, 1319-1325 (2003).
2. B. Yount, K. M. Curtis, E. A. Fritz, L. E. Hensley, P. B. Jahrling, E. Prentice, M. R. Denison, T. W. Geisbert, and R. S. Baric, Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus, Proc. Natl. Acad. Sci. USA 100, 12995-13000 (2003).
3. F. Almazán, J. M. González, Z. Pénzes, A. Izeta, E. Calvo, J. Plana-Durán, and L. Enjuanes, Engineering the largest RNA virus genome as an infectious bacterial artificial chromosome, Proc. Natl. Acad. Sci. USA 97, 5516-5521 (2000).
4. J. Ortego, D. Escors, H. Laude, and L. Enjuanes, Generation of a replication-competent, propagation-deficient virus vector based on the transmissible gastroenteritis coronavirus genome, J. Virol. 76, 11518-11529 (2002).
5. L. Kuo and P. S. Masters, The small envelope protein E is not essential for murine coronavirus replication, J. Virol. 77, 4597-4608 (2003).
6. F. Almazán, C. Galán, and L. Enjuanes, The nucleoprotein is required for efficient coronavirus genome replication, J. Virol. 78, 12683-12688 (2004).
7. E. J. Snijder, P. J. Bredenbeek, J. C. Dobbe, V. Thiel, J. Ziebuhr, L. L. Poon, Y. Guan, M. Rozanov, W. J. Spaan, and A. E. Gorbalenya, Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 linage, J. Mol. Biol. 331, 991-1004 (2003).