Lipid-based nanoparticles as nonviral gene delivery vectors

Methods in Molecular Biology

Volumn 1025, Issue , 2013, Pages 269-279

  Pezzoli, Daniele ^a   Kajaste Rudnitski, Anna ^b   Chiesa, Roberto ^a   Candiani, Gabriele ^a  

^a POLITECNICO DI MILANO   (Italy)

^b SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

Author keywords

Cationic liposomes; Charge ratio; Cytotoxicity; DLS; Extrusion; Firefly luciferase; Gene delivery; Transfection efficiency

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; NANOPARTICLE;

ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; LIPOSOMAL GENE DELIVERY SYSTEM; MICROELECTROPHORESIS; PRIORITY JOURNAL; SURFACE CHARGE;

EID: 84934435450     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-462-3_21     Document Type: Article

References (11)

1. Candiani G, Pezzoli D, Cabras M, Ristori S, Pellegrini C, Kajaste-Rudnitski A, Vicenzi E, Sala C, Zanda M (2008) A dimerizable cationic lipid with potential for gene delivery. J Gene Med 10:637-645
2. Candiani G, Frigerio M, Viani F, Verpelli C, Sala C, Chiamenti L, Zaffaroni N, Folini M, Sani M, Panzeri W, Zanda M (2007) Dimerizable redox-sensitive triazine-based cationic lipids for in vitro gene delivery. ChemMedChem 2:292-296
3. Pezzoli D, Candiani G, Cabras S, Giordano C, Daniele F, Cigada A (2008) Liposomes versus micelles as gene delivery vectors. Biomed Pharmacother 62:493
4. Candiani G, Pezzoli D, Ciani L, Chiesa R, Ristori S (2010) Bioreducible liposomes for gene delivery: From the formulation to the mechanism of action. PLoS One 5:e13430
5. Felgner PL, Gadek TR, Holm M, Roman R, Chan HW, Wenz M, Northrop JP, Ringold GM, Danielsen M (1987) Lipofection - a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci U S A 84:7413-7417
6. Ciani L, Ristori S, Calamai L, Martini G (2004) DOTAP/DOPE and DC-Chol/DOPE lipoplexes for gene delivery: zeta potential measurements and electron spin resonance spectra. Bba-Biomembranes 1664: 70-79
7. Hui SW, Langner M, Zhao YL, Ross P, Hurley E, Chan K (1996) The role of helper lipids in cationic liposome-mediated gene transfer. Biophys J 71:590-599
8. Ristori S, Ciani L, Candiani G, Battistini C, Frati A, Grillo I, In M (2012) Complexing a small interfering RNA with divalent cationic surfactants. Soft Matter 8:749-756
9. van Gaal EVB, van Eijk R, Oosting RS, Kok RJ, Hennink WE, Crommelin DJA, Mastrobattista E (2011) How to screen non-viral gene delivery systems in vitro? J Control Release 154:218-232
10. Pezzoli D, Olimpieri F, Malloggi C, Bertini S, Volonterio A, Candiani G (2012) Chitosangraft- branched polyethylenimine copolymers: influence of degree of grafting on transfection behavior. PLoS One 7:e34711
11. Macdonald RC, Macdonald RI, Menco BPM, Takeshita K, Subbarao NK, Hu LR (1991) Small-volume extrusion apparatus for preparation of large unilamellar vesicles. Biochim Biophys Acta 1061:297-303