Disposition and dynamics: Interdomain orientations in troponin

Advances in Experimental Medicine and Biology

Volumn 592, Issue , 2007, Pages 59-70

  Hoffman, Ryan M B ^a   Sykes, Brian D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CHEMOKINE RECEPTOR CXCR6; TROPONIN;

CONFERENCE PAPER; ELECTROCHEMISTRY; MUSCLE CONTRACTION; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STOICHIOMETRY; THERMODYNAMICS;

EID: 84934435143     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-4-431-38453-3_7     Document Type: Conference Paper

References (29)

1. S. Ebashi, Regulatory mechanism of muscle contraction with special reference to the Ca-troponin-tropomyosin system. Essays Biochem. 10, 1-36 (1974).
2. 2+ regulation of muscle contraction. Biochemistry 13(13), 2697-2703 (1974).
3. 2+ binding proteins. Biochemistry 24(20), 5298-5302 (1985).
4. M. Sundaralingam, R. Bergstrom, G. Strasburg, S. T. Rao, P. Roychowdhury, M. Greaser, and B. C. Wang, Molecular structure of troponin C from chicken skeletal muscle at 3-angstrom resolution. Science 227(4689), 945-948 (1985).
5. S. M. Gagne, S. Tsuda, M. X. Li, L. B. Smillie, and B. D. Sykes, Structures of the troponin C regulatory domains in the apo and calcium-saturated states. Nat. Struct. Biol. 2(9), 784-789 (1995).
6. C. M. Slupsky, and B. D. Sykes, NMR solution structure of calcium-saturated skeletal muscle troponin C. Biochemistry 34(49), 15953-15964 (1995).
7. 2+-induced conformational transition of troponin C. A trigger for muscle contraction. J. Biol. Chem. 261(6), 2638-2644 (1986).
8. C. M. Slupsky, The NMR Solution Structure of Calcium-Saturated Skeletal Muscle Troponin C. Ph.D. thesis, University of Alberta, Dept. of Biochemistry (1995).
9. 15N-NMR relaxation measurements. Eur. J. Biochem. 230(3), 1014-1024 (1995).
10. A. C. Murray, and C. M. Kay, Hydrodynamic and optical properties of troponin A. Demonstration of a conformational change upon binding calcium ion. Biochemistry 11(14), 2622-2627 (1972).
11. D. M. Byers, and C. M. Kay, Hydrodynamic properties of bovine cardiac troponin C. Biochemistry 21(2), 229-233 (1982).
12. J. Gulati, A. B. Akella, H. Su, E. L. Mehler, and H. Weinstein, Functional role of arginine-11 in the N-terminal helix of skeletal troponin C: combined mutagenesis and molecular dynamics investigation. Biochemistry 34(22), 7348-7355 (1995).
13. S. M. Gagne, M. X. Li, and B. D. Sykes, Mechanism of direct coupling between binding and induced structural change in regulatory calcium binding proteins. Biochemistry 36(15), 4386-4392 (1997).
14. N. C. Strynadka, and M. N. G. James, Crystal structures of the helix-loop-helix calcium-binding proteins. Annu. Rev. Biochem. 58, 951-998 (1989).
15. S. K. Sia, M. X. Li, L. Spyracopoulos, S. M. Gagne, W. Liu, J. A. Putkey, and B. D. Sykes, Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain. J. Biol. Chem. 272(29), 18216-18221 (1997).
16. S. M. Gagne, M. X. Li, R. T. McKay, and B. D. Sykes, The NMR angle on troponin C. Biochem. Cell Biol. 76(2-3), 302-312 (1998).
17. 2+-dependent regulation of muscle contraction. J. Mol. Biol. 271(5), 728-750 (1997).
18. 2+-regulated Muscle Relaxation at Interaction Sites of Troponin with Actin and Tropomyosin. J. Mol. Biol. 352(1), 178-201 (2005).
19. 2+-saturated form. Nature 424(6944), 35-41 (2003).
20. B. D. Sykes, Pulling the calcium trigger. Nat. Struct. Biol. 10(8), 588-589 (2003).
21. J. R. Pearlstone, and L. B. Smillie, The interaction of rabbit skeletal muscle troponin-T fragments with troponin-I. Can. J. Biochem. Cell Biol. 63(3), 212-218 (1985).
22. 2+-regulated structural changes in troponin. Proc. Natl. Acad. Sci. USA 102(14), 5038-5043 (2005).
23. B. Halle, Flexibility and packing in proteins. Proc. Natl. Acad. Sci. USA 99(3), 1274-1279 (2002).
24. 2+-binding to troponin C. Adv. Exp. Med. Biol. 453, 157-167 (1998).
25. J. Soman, T. Tao, and G. N. J. Phillips, Conformational variation of calcium-bound troponin C. Proteins 37(4), 510-511 (1999).
26. M. E. Wall, J. B. Clarage, and G. N. Phillips, Motions of calmodulin characterized using both Bragg and diffuse X-ray scattering. Structure 5(12), 1599-1612 (1997).
27. T. M. A. Blumenschein, D. B. Stone, R. J. Fletterick, R. A. Mendelson, and B. D. Sykes, Calcium-dependent changes in the flexibility of the regulatory domain of troponin C in the troponin complex. J. Biol. Chem. 280(23), 21924-21932 (2005).
28. T. M. A. Blumenschein, D. B. Stone, R. J. Fletterick, R. A. Mendelson, and B. D. Sykes, Dynamics of the C-terminal region of TnI in the troponin complex in solution. Biophys. J. 90(7), 2436-2444 (2006).
29. B. A. Shoemaker, J. J. Portman, and P. G. Wolynes, Speeding molecular recognition by using the folding funnel: the fly-casting mechanism. Proc. Natl. Acad. Sci. USA 97(16), 8868-8873 (2000).