Molecular mechanisms of cardioprotection by taurine on ischemia-induced apoptosis in cultured cardiomyocytes

Advances in Experimental Medicine and Biology

Volumn 583, Issue , 2006, Pages 257-263

  Takahashi, Kyoko ^a   Takatani, Tomoka ^a   Uozumi, Yoriko ^a   Ito, Takashi ^a   Matsuda, Takahisa ^a   Fujio, Yasushi ^a   Schaffer, Stephen W ^b   Azuma, Junichi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84934434696     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-33504-9_28     Document Type: Conference Paper

References (9)

1. Fujio, Y., Nguyen, Wencker, D., Kitsis,, R. N., and Walsh, K., 2000, Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart, Circulation 101:660-667.
2. Garg, S., Narula, J., and Chandrashekhar, 2005, Apoptosis and heart failure: clinical relevance and therapeutic target, J. Mol. Cell. Cardiol. 38:3-79.
3. Roysommuti, S., Azuma, J., Takahashi, K., Mozaffari, M., and Schaffer, S. W., 2003, Taurine cytoprotection: from cell to system, Thai J. Physiol. Sci. 16:17-27.
4. Schaffer, S. W., Azuma, J., Takahashi, K., and Mozaffari, M., 2003, Why is taurine cytoprotective? Adv. Exp. Med. Biol. 526:307-321.
5. Takahashi, K., Ohyabu, Y., Schaffer, S. W., and Azuma, J., 2000, Taurine prevents ischemia damage in cultured neonatal rat cardiomyocytes, Adv. Exp. Med. Biol. 483:109-116.
6. Takahashi, K., Ouyabu, Y., Schaffer, S. W., and Azuma, J., 2001, Cellular characterization of in vitro cell culture model of seal-induced cardiac ischemia, J. Pharm. Pharmacol. 53:379-386.
7. Takahashi, K., Ohyabu, Y., Takahashi, K., Solodushko, V., Itho, T., Schaffer, S. W., Azuma, J., 2003, Taurine renders the cell resistant to ischemia-induced injury in cultured neonatal rat cardiomyocytes, J. Cardiovasc. Pharmacol. 41:726-733.
8. Takatani, T., Takahashi, K., Uozumi, Y., Matsuda, T., Ito, T., Fujio, Y., and Azuma, J., 2004a, Taurine prevents the ischemia-induced apoptosis in cultured neonatal rat cardiomyocytes through Akt/caspase-9 pathway, Biochem. Biophys. Res. Commun. 316:484-489.
9. Takatani, T., Takahashi, K., Uozumi, Y., Shikata, E., Yamamoto, Y., Ito, T., Matsuda, T., Fujio, Y., Schaffer, S. W., and Azuma, J., 2004b, Taurine inhibits apoptosis by preventing formation of the Apaf-1/caspase-9 apoptosome, J. Am. J. Physiol. 287:C949-C953.