Phosphorylation-dependent regulation of satb1, the higher-order chromatin organizer and global gene regulator

Methods in Molecular Biology

Volumn 647, Issue , 2010, Pages 317-335

  Notani, Dimple ^a   Limaye, Amita S ^a   Kumar, P Pavan ^a   Galande, Sanjeev ^a  

^a NATIONAL CENTRE FOR CELL SCIENCE   (India)

Author keywords

Chromatin organization; Gene expression; HDAC1; Immunoprecipitation; Phosphorylation; Protein kinase C; Reporter assay; SATB1

Indexed keywords

EID: 84934434375     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60761-738-9_20     Document Type: Article

References (21)

1. de Belle I, Cai S, Kohwi-Shigematsu T (1998) The genomic sequences bound to special AT-rich sequence-binding protein 1 (SATB1) in vivo in Jurkat T cells are tightly associated with the nuclear matrix at the bases of the chromatin loops. J Cell Biol 141:335-348
2. Cai S, Han HJ, Kohwi-Shigematsu T (2003) Tissue-specific nuclear architecture and gene expression regulated by SATB1. Nat Genet 34:42-51 (Pubitemid 36548789)
3. Cai S, Lee CC, Kohwi-Shigematsu T (2006) SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes. Nat Genet 38:1278-1288 (Pubitemid 44646290)
4. Kumar PP, Bischof O, Purbey PK, Notani D, Urlaub H, Dejean A, Galande S (2007) Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus. Nat Cell Biol 9:45-56 (Pubitemid 46024196)
5. Galande S, Purbey PK, Notani D, Kumar PP (2007) The third dimension of gene regulation: Organization of dynamic chromatin loopscape by SATB1. Curr Opin Genet Dev 27:408-414 (Pubitemid 350019562)
6. Yasui D, Miyano M, Cai S, Varga-Weisz P, Kohwi-Shigematsu T (2002) SATB1 targets chromatin remodelling to regulate genes over long distances. Nature 419:641-645
7. Kumar PP, Purbey PK, Ravi DS, Mitra D, Galande S (2005) Displacement of SATB1-bound histone deacetylase 1 corepressor by the human immunodeficiency virus type 1 transactivator induces expression of interleukin-2 and its receptor in T cells. Mol Cell Biol 25:1620-1633 (Pubitemid 40280132)
8. Kumar PP, Purbey PK, Sinha CK, Notani D, Limaye A, Jayani RS, Galande S (2006) Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo. Mol Cell 22:231-243
9. Dickinson LA, Dickinson CD, Kohwi-Shigematsu T (1997) An atypical homeodomain in SATB1 promotes specific recognition of the key structural element in a matrix attachment region. J Biol Chem 272:11463-11470 (Pubitemid 27184155)
10. Purbey PK, Singh S, Kumar PP, Mehta S, Ganesh KN, Mitra D, Galande S (2008) PDZ domain-mediated dimerization and homeodomain-directed specificity are required for high-affinity DNA binding by SATB1. Nucleic Acids Res 36:2107-2122 (Pubitemid 351566987)
11. Galande S, Dickinson LA, Mian IS, Sikorska M, Kohwi-Shigematsu T (2001) SATB1 cleavage by caspase 6 disrupts PDZ domainmediated dimerization, causing detachment from chromatin early in T-cell apoptosis. Mol Cell Biol 21:5591-5604 (Pubitemid 32702462)
12. Chan HM, La Thangue NB (2001) p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J Cell Sci 114:2363-2373 (Pubitemid 32684792)
13. Poux AN, Marmorstein R (2003) Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates. Biochemistry 42:14366-14374 (Pubitemid 37531982)
14. Zhong H, Voll RE, Ghosh S (1998) Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol Cell 1:661-671 (Pubitemid 128379244)
15. Lambert PF, Kashanchi F, Radonovich MF, Shiekhattar R, Brady JN (1998) Phosphorylation of p53 serine 15 increases interaction with CBP. J Biol Chem 273:33048-33053 (Pubitemid 28557701)
16. Tintignac LA, Sirri V, Leibovitch MP, Lecluse Y, Castedo M, Metivier D, Kroemer G, Leibovitch SA (2004) Mutant MyoD lacking Cdc2 phosphorylation sites delays M-phase entry. Mol Cell Biol 24:1809-1821 (Pubitemid 38167101)
17. Puri PL, Iezzi S, Stiegler P, Chen TT, Schiltz RL, Muscat GE, Giordano A, Kedes L, Wang JY, Sartorelli V (2001) Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis. Mol Cell 8:885-897 (Pubitemid 33030221)
18. Hug H, Sarre TF (1993) Protein kinase C isoenzymes: Divergence in signal transduction? Biochem J 291:329-343 (Pubitemid 23127010)
19. Strulovici B, Daniel-Issakani S, Baxter G, Knopf J, Sultzman L, Cherwinski H, Nestor J Jr, Webb DR, Ransom J (1991) Distinct mechanisms of regulation of protein kinase C epsilon by hormones and phorbol diesters. J Biol Chem 266:168-173 (Pubitemid 21906105)
20. Dignam JD, Lebovitz RM, Roeder RG (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489
21. Rampalli S, Kulkarni A, Kumar P, Mogare D, Galande S, Mitra D, Chattopadhyay S (2003) Stimulation of Tat-independent transcriptional processivity from the HIV-1 LTR promoter by matrix attachment regions. Nucleic Acids Res 31:3248-3256 (Pubitemid 37441784)