Activin A can induce definitive endoderm differentiation from human parthenogenetic embryonic stem cells

Biotechnology Letters

Volumn 37, Issue 8, 2015, Pages 1711-1717

  Wang, Zhiqiang ^a   Li, Wenliang ^a   Chen, Tianxing ^b   Yang, Jun ^a   Wen, Zhengqi ^a   Yan, Xinmin ^c   Shen, Tao ^c   Liang, Rui ^b  

^a KUNMING MEDICAL UNIVERSITY   (China)

^b First People's Hospital of Yunnan Province   (China)

^c Institute of Clinical and Basic Medicine Research of the First People's Hospital of Yunnan Province   (China)

Author keywords

Activin A; Definitive endoderm; Differentiation; Human foreskin fibroblasts; Human parthenogenetic embryonic stem cells; Stem cells

Indexed keywords

CELL CULTURE; CELL SIGNALING; CELLS; CYTOLOGY; DIFFERENTIATION (CALCULUS); GLYCOPROTEINS;

ACTIVIN A; DE-DIFFERENTIATION; DEFINITIVE ENDODERM; EMBRYONIC STEM CELLS; LOW DOSE; OPTIMAL CONCENTRATION;

STEM CELLS;

ACTIVIN; ACTIVIN A; BIOLOGICAL MARKER; BRACHYURY PROTEIN; CHEMOKINE RECEPTOR CXCR4; CXCR4 PROTEIN, HUMAN; FETOPROTEIN; SOX17 PROTEIN, HUMAN; T BOX TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX;

CELL DIFFERENTIATION; CHEMISTRY; DRUG EFFECTS; EMBRYONIC STEM CELL; ENDODERM; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM;

ACTIVINS; BIOMARKERS; CELL DIFFERENTIATION; EMBRYONIC STEM CELLS; ENDODERM; FETAL PROTEINS; HUMANS; RECEPTORS, CXCR4; SOXF TRANSCRIPTION FACTORS; T-BOX DOMAIN PROTEINS;

EID: 84933675275     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-015-1829-x     Document Type: Article

References (18)

1. D’Amour KA, Agulnick AD, Eliazer S et al (2005) Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol 23:1534–1541
2. Daughtry B, Mitalipov S (2014) Concise review: parthenote stem cells for regenerative medicine: genetic, epigenetic, and developmental features. Stem Cells Transl Med 3:290–298
3. Eiselleova L, Peterkova I, Neradil J et al (2008) Comparative study of mouse and human feeder cells for human embryonic stem cells. Int J Dev Biol 52:353–363
4. Fei T, Zhu S, Xia K et al (2010) Smad2 mediates activin/Nodal signaling in mesendoderm differentiation of mouse embryonic stem cells. Cell Res 20:1306–1318
5. Guo S, Mao X, He F, Liu H, Ming L (2014) Activin A supplement in the hESCs culture enhances the endoderm differentiation efficiency. Cell Biol Int 38:849–856
6. Hao J, Zhu W, Sheng C, Yu Y, Zhou Q (2009) Human parthenogenetic embryonic stem cells: one potential resource for cell therapy. Sci China Ser C 52:599–602
7. Kaur J, Tilkins ML (2013) Methods for culturing human embryonic stem cells on feeders. Methods Mol Biol 997:93–113
8. Kim PT, Ong CJ (2012) Differentiation of definitive endoderm from mouse embryonic stem cells. Results Probl Cell Differ 55:303–319
9. Kopper O, Benvenisty N (2012) Stepwise differentiation of human embryonic stem cells into early endoderm derivatives and their molecular characterization. Stem Cell Res 8:335–345
10. Kraus MR, Grapin-Botton A (2012) Patterning and shaping the endoderm in vivo and in culture. Curr Opin Genet Dev 22:347–353
11. Kubo A, Shinozaki K, Shannon JM et al (2004) Development of definitive endoderm from embryonic stem cells in culture. Development 131:1651–1662
12. Lin G, OuYang Q, Zhou X et al (2007) A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure. Cell Res 17:999–1007
13. Lu Z, Zhu W, Yu Y et al (2010) Derivation and long-term culture of human parthenogenetic embryonic stem cells using human foreskin feeders. J Assist Reprod Genet 27:285–291
14. Payne C, King J, Hay D (2011) The role of activin/nodal and Wnt signaling in endoderm formation. Vitam Horm 85:207–216
15. Taupin P (2011) Parthenogenetically activated human oocytes and parthenogenetic embryonic stem cells: US20100233143. Expert Opin Ther Pat 21:1281–1283
16. Tomizawa M, Shinozaki F, Sugiyama T et al (2011) Activin A maintains pluripotency markers and proliferative potential of human induced pluripotent stem cells. Exp Ther Med 2:405–408
17. Turovets N, Fair J, West R et al (2012) Derivation of high-purity definitive endoderm from human parthenogenetic stem cells using an in vitro analog of the primitive streak. Cell Transplant 21:217–234
18. Xiao L, Yuan X, Sharkis SJ (2006) Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells. Stem Cells 24:1476–1486