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Volumn 21, Issue 3, 2015, Pages 226-229

Roche perspectives on Tamiflu

Author keywords

Data sharing; Independent analysis; Influenza; Oseltamivir; Roche perspective

Indexed keywords

ANTIBIOTIC AGENT; ANTIVIRUS AGENT; OSELTAMIVIR; ENZYME INHIBITOR; SIALIDASE;

EID: 84933533896     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1016/j.cmi.2015.01.014     Document Type: Review
Times cited : (5)

References (40)
  • 1
    • 0034084227 scopus 로고    scopus 로고
    • Discovery and development of GS 4104 (oseltamivir): an orally active influenza neuraminidase inhibitor
    • Lew W., Chen X., Kim C.U. Discovery and development of GS 4104 (oseltamivir): an orally active influenza neuraminidase inhibitor. Curr Med Chem 2000, 7:663-672.
    • (2000) Curr Med Chem , vol.7 , pp. 663-672
    • Lew, W.1    Chen, X.2    Kim, C.U.3
  • 3
    • 79960720836 scopus 로고    scopus 로고
    • Available at: [accessed 10.12.14].
    • Tamiflu. Highlights of prescribing information. Available at: [accessed 10.12.14]. http://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021087s060,021246s043lbl.pdf.
    • Highlights of prescribing information
  • 4
    • 17744412173 scopus 로고    scopus 로고
    • Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: a randomized controlled trial. US Oral Neuraminidase Study Group
    • Treanor J.J., Hayden F.G., Vrooman P.S., Barbarash R., Bettis R., Riff D., et al. Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: a randomized controlled trial. US Oral Neuraminidase Study Group. JAMA 2000, 283:1016-1024.
    • (2000) JAMA , vol.283 , pp. 1016-1024
    • Treanor, J.J.1    Hayden, F.G.2    Vrooman, P.S.3    Barbarash, R.4    Bettis, R.5    Riff, D.6
  • 5
    • 0034720503 scopus 로고    scopus 로고
    • Efficacy and safety of oseltamivir in treatment of acute influenza: a randomised controlled trial. Neuraminidase Inhibitor Flu Treatment Investigator Group
    • [Erratum: Lancet 2000; 356: 1856]
    • Nicholson K.G., Aoki F.Y., Osterhaus A.D., Trottier S., Carewicz O., Mercier C.H., et al. Efficacy and safety of oseltamivir in treatment of acute influenza: a randomised controlled trial. Neuraminidase Inhibitor Flu Treatment Investigator Group. Lancet 2000, 355:1845-1850. [Erratum: Lancet 2000; 356: 1856].
    • (2000) Lancet , vol.355 , pp. 1845-1850
    • Nicholson, K.G.1    Aoki, F.Y.2    Osterhaus, A.D.3    Trottier, S.4    Carewicz, O.5    Mercier, C.H.6
  • 6
    • 0035121720 scopus 로고    scopus 로고
    • Oral oseltamivir treatment of influenza in children
    • [Erratum: Pediatr Infect Dis J 2001; 20: 421]
    • Whitley R.J., Hayden F.G., Reisinger K.S., Young N., Dutkowski R., Ipe D., et al. Oral oseltamivir treatment of influenza in children. Pediatr Infect Dis J 2001, 20:127-133. [Erratum: Pediatr Infect Dis J 2001; 20: 421].
    • (2001) Pediatr Infect Dis J , vol.20 , pp. 127-133
    • Whitley, R.J.1    Hayden, F.G.2    Reisinger, K.S.3    Young, N.4    Dutkowski, R.5    Ipe, D.6
  • 7
    • 0035857389 scopus 로고    scopus 로고
    • Oseltamivir Post Exposure Prophylaxis Investigator Group. Effectiveness of oseltamivir in preventing influenza in household contacts: a randomized controlled trial
    • Welliver R., Monto A.S., Carewicz O., Schatteman E., Hassman M., Hedrick J., et al. Oseltamivir Post Exposure Prophylaxis Investigator Group. Effectiveness of oseltamivir in preventing influenza in household contacts: a randomized controlled trial. JAMA 2001, 285:748-754.
    • (2001) JAMA , vol.285 , pp. 748-754
    • Welliver, R.1    Monto, A.S.2    Carewicz, O.3    Schatteman, E.4    Hassman, M.5    Hedrick, J.6
  • 8
    • 1142309473 scopus 로고    scopus 로고
    • Management of influenza in households: a prospective, randomized comparison of oseltamivir treatment with or without postexposure prophylaxis
    • Hayden F.G., Belshe R., Villanueva C., Lanno R., Hughes C., Small I., et al. Management of influenza in households: a prospective, randomized comparison of oseltamivir treatment with or without postexposure prophylaxis. JInfect Dis 2004, 189:440-449.
    • (2004) JInfect Dis , vol.189 , pp. 440-449
    • Hayden, F.G.1    Belshe, R.2    Villanueva, C.3    Lanno, R.4    Hughes, C.5    Small, I.6
  • 9
    • 14944355937 scopus 로고    scopus 로고
    • Oral oseltamivir improves pulmonary function and reduces exacerbation frequency for influenza-infected children with asthma
    • Johnston S.L., Ferrero F., Garcia M.L., Dutkowski R. Oral oseltamivir improves pulmonary function and reduces exacerbation frequency for influenza-infected children with asthma. Pediatr Infect Dis J 2005, 24:225-232.
    • (2005) Pediatr Infect Dis J , vol.24 , pp. 225-232
    • Johnston, S.L.1    Ferrero, F.2    Garcia, M.L.3    Dutkowski, R.4
  • 10
    • 84865704628 scopus 로고    scopus 로고
    • Efficacy and safety of oral oseltamivir for influenza prophylaxis in transplant recipients
    • Ison M.G., Szakaly P., Shapira M.Y., Kriván G., Nist A., Dutkowski R. Efficacy and safety of oral oseltamivir for influenza prophylaxis in transplant recipients. Antivir Ther 2012, 17:955-964.
    • (2012) Antivir Ther , vol.17 , pp. 955-964
    • Ison, M.G.1    Szakaly, P.2    Shapira, M.Y.3    Kriván, G.4    Nist, A.5    Dutkowski, R.6
  • 11
    • 84875980586 scopus 로고    scopus 로고
    • Global assessment of resistance to neuraminidase inhibitors, 2008-2011: the Influenza Resistance Information Study (IRIS)
    • [Erratum: Clin Infect Dis 2014; 58: 1203]
    • Whitley R.J., Boucher C.A., Lina B., Nguyen-Van-Tam J.S., Osterhaus A., Schutten M., et al. Global assessment of resistance to neuraminidase inhibitors, 2008-2011: the Influenza Resistance Information Study (IRIS). Clin Infect Dis 2013, 56:1197-1205. [Erratum: Clin Infect Dis 2014; 58: 1203].
    • (2013) Clin Infect Dis , vol.56 , pp. 1197-1205
    • Whitley, R.J.1    Boucher, C.A.2    Lina, B.3    Nguyen-Van-Tam, J.S.4    Osterhaus, A.5    Schutten, M.6
  • 12
    • 84907864513 scopus 로고    scopus 로고
    • The posology of oseltamivir in infants with influenza infection using a population pharmacokinetic approach
    • Kamal M.A., Acosta E.P., Kimberlin D.W., Gibiansky L., Jester P., Niranjan V., et al. The posology of oseltamivir in infants with influenza infection using a population pharmacokinetic approach. Clin Pharmacol Ther 2014, 96:380-389.
    • (2014) Clin Pharmacol Ther , vol.96 , pp. 380-389
    • Kamal, M.A.1    Acosta, E.P.2    Kimberlin, D.W.3    Gibiansky, L.4    Jester, P.5    Niranjan, V.6
  • 13
    • 79952217106 scopus 로고    scopus 로고
    • US Centers for Disease Control and Prevention. Antiviral agents for the treatment and chemoprophylaxis of influenza recommendations of the Advisory Committee on Immunization Practices (ACIP)
    • Fiore A.E., Fry A., Shay D., Gubareva L., Bresee J.S., Uyeki T.M. US Centers for Disease Control and Prevention. Antiviral agents for the treatment and chemoprophylaxis of influenza recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Morb Mortal Wkly Rep 2011, 60:1-28.
    • (2011) MMWR Morb Mortal Wkly Rep , vol.60 , pp. 1-28
    • Fiore, A.E.1    Fry, A.2    Shay, D.3    Gubareva, L.4    Bresee, J.S.5    Uyeki, T.M.6
  • 14
    • 84933511621 scopus 로고    scopus 로고
    • Available at:, [accessed 10.12.14]
    • US Centers for Disease Control and Prevention CDC recommendations for influenza antiviral medications remain unchanged 10 April 2014, Available at:, [accessed 10.12.14]. http://www.cdc.gov/media/haveyouheard/stories/Influenza_antiviral2.html.
    • (2014) CDC recommendations for influenza antiviral medications remain unchanged
  • 16
    • 80052272722 scopus 로고    scopus 로고
    • Available at:, [accessed 10.12.14]
    • European Centre for Disease Prevention and Control ECDC Interim guidance: public health use of influenza antivirals during influenza pandemics 18 August 2009, Available at:, [accessed 10.12.14]. http://www.ecdc.europa.eu/en/publications/Publications/0907_GUI_Public_Health_use_of_Influenza_Antivirals_during_Influenza_Pandemic.pdf.
    • (2009) ECDC Interim guidance: public health use of influenza antivirals during influenza pandemics
  • 17
    • 84933525473 scopus 로고    scopus 로고
    • Available at: [accessed 30.11.14].
    • World Health Organization. Essential medicines selection: oseltamivir (inclusion). Available at: [accessed 30.11.14]. http://www.who.int/selection_medicines/committees/expert/17/application/oseltamivir/en/.
    • Essential medicines selection: oseltamivir (inclusion)
  • 18
    • 0042819522 scopus 로고    scopus 로고
    • Reduction in the symptoms and complications of influenza A and B in patients treated with oseltamivir (the Time-to-Treatment Study Group)
    • September 7-10 2000, New Orleans
    • Treanor J. Reduction in the symptoms and complications of influenza A and B in patients treated with oseltamivir (the Time-to-Treatment Study Group). The 38th Annual Meeting of the Infectious Diseases Society of America, September 7-10 2000, New Orleans. Abstract 611.
    • The 38th Annual Meeting of the Infectious Diseases Society of America
    • Treanor, J.1
  • 19
    • 33746659240 scopus 로고    scopus 로고
    • Oral oseltamivir reduces febrile illness in patients considered at high risk of influenza complications [abstract W22-7]
    • Excerpta Medica
    • Martin C., Mahoney P., Ward P. Oral oseltamivir reduces febrile illness in patients considered at high risk of influenza complications [abstract W22-7]. Options for the control of influenza IV 2001, 807-811. Excerpta Medica.
    • (2001) Options for the control of influenza IV , pp. 807-811
    • Martin, C.1    Mahoney, P.2    Ward, P.3
  • 23
    • 84898618697 scopus 로고    scopus 로고
    • Response to: Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments
    • Clinch B., Smith J., Kenwright A. Response to: Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments. BMJ 2014, 348:g2545.
    • (2014) BMJ , vol.348 , pp. g2545
    • Clinch, B.1    Smith, J.2    Kenwright, A.3
  • 25
    • 0042259159 scopus 로고    scopus 로고
    • Impact of oseltamivir treatment on influenza-related lower respiratory tract complications and hospitalizations
    • Kaiser L., Wat C., Mills T., Mahoney P., Ward P., Hayden F. Impact of oseltamivir treatment on influenza-related lower respiratory tract complications and hospitalizations. Arch Intern Med 2003, 163:1667-1672.
    • (2003) Arch Intern Med , vol.163 , pp. 1667-1672
    • Kaiser, L.1    Wat, C.2    Mills, T.3    Mahoney, P.4    Ward, P.5    Hayden, F.6
  • 26
    • 79960757788 scopus 로고    scopus 로고
    • Oseltamivir and risk of lower respiratory tract complications in patients with flu symptoms: a meta-analysis of eleven randomized clinical trials
    • Hernán M.A., Lipsitch M. Oseltamivir and risk of lower respiratory tract complications in patients with flu symptoms: a meta-analysis of eleven randomized clinical trials. Clin Infect Dis 2011, 53:277-279.
    • (2011) Clin Infect Dis , vol.53 , pp. 277-279
    • Hernán, M.A.1    Lipsitch, M.2
  • 27
    • 84875580020 scopus 로고    scopus 로고
    • Effectiveness of oseltamivir in adults: a meta-analysis of published and unpublished clinical trials
    • Ebell M.H., Call M., Shinholser J. Effectiveness of oseltamivir in adults: a meta-analysis of published and unpublished clinical trials. Fam Pract 2012, 30:125-133.
    • (2012) Fam Pract , vol.30 , pp. 125-133
    • Ebell, M.H.1    Call, M.2    Shinholser, J.3
  • 28
    • 0014671798 scopus 로고
    • Therapeutic efficacy of amantadine HC1 and rimantadine HCl in naturally occurring influenza A2 respiratory illness in man
    • Wingfield W.L., Pollack D., Grunert R. Therapeutic efficacy of amantadine HC1 and rimantadine HCl in naturally occurring influenza A2 respiratory illness in man. NEngl J Med 1969, 281:579.
    • (1969) NEngl J Med , vol.281 , pp. 579
    • Wingfield, W.L.1    Pollack, D.2    Grunert, R.3
  • 30
    • 84872384525 scopus 로고    scopus 로고
    • Bacterial coinfection in influenza: a grand rounds review
    • Chertow D.S., Memoli M.J. Bacterial coinfection in influenza: a grand rounds review. JAMA 2013, 309:275-282.
    • (2013) JAMA , vol.309 , pp. 275-282
    • Chertow, D.S.1    Memoli, M.J.2
  • 32
    • 84897142275 scopus 로고    scopus 로고
    • Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data
    • PRIDE Consortium Investigators, Nguyen-Van-Tam JS
    • Muthuri S.G., Venkatesan S., Myles P.R., Leonardi-Bee J., Al Khuwaitir T.S., Al Mamun A., et al. Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data. Lancet Respir Med 2014, 2:395-404. PRIDE Consortium Investigators, Nguyen-Van-Tam JS.
    • (2014) Lancet Respir Med , vol.2 , pp. 395-404
    • Muthuri, S.G.1    Venkatesan, S.2    Myles, P.R.3    Leonardi-Bee, J.4    Al Khuwaitir, T.S.5    Al Mamun, A.6
  • 33
    • 45849142570 scopus 로고    scopus 로고
    • Study of the impact of oseltamivir on the risk for pneumonia and other outcomes of influenza, 2000-2005
    • Peters P.H., Moscona A., Schulman K.L., Barr C.E. Study of the impact of oseltamivir on the risk for pneumonia and other outcomes of influenza, 2000-2005. Medscape J Med 2008, 10:131.
    • (2008) Medscape J Med , vol.10 , pp. 131
    • Peters, P.H.1    Moscona, A.2    Schulman, K.L.3    Barr, C.E.4
  • 34
    • 67649611236 scopus 로고    scopus 로고
    • Effects of oseltamivir on influenza-related complications in children with chronic medical conditions
    • Piedra P.A., Schulman K.L., Blumentals W.A. Effects of oseltamivir on influenza-related complications in children with chronic medical conditions. Pediatrics 2009, 124:170-178.
    • (2009) Pediatrics , vol.124 , pp. 170-178
    • Piedra, P.A.1    Schulman, K.L.2    Blumentals, W.A.3
  • 35
    • 84906049988 scopus 로고    scopus 로고
    • Available at:, [accessed 10.12.14]
    • US Centers for Disease Control and Prevention Influenza antiviral medications: summary for clinicians 3 December 2014, Available at:, [accessed 10.12.14]. http://www.cdc.gov/flu/professionals/antivirals/summary-clinicians.htm.
    • (2014) Influenza antiviral medications: summary for clinicians
  • 39
    • 84869174502 scopus 로고    scopus 로고
    • European governments should sue Roche and prescribers should boycott its drugs [electronic response to Godlee F. Open letter to Roche about oseltamivir trial data]
    • Gøtzsche P.C. European governments should sue Roche and prescribers should boycott its drugs [electronic response to Godlee F. Open letter to Roche about oseltamivir trial data]. BMJ 2012, 345:e7689.
    • (2012) BMJ , vol.345 , pp. e7689
    • Gøtzsche, P.C.1
  • 40
    • 84929029181 scopus 로고    scopus 로고
    • Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials
    • Dobson J., Whitley R.J., Pocock S., Monto A.S. Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials. Lancet 2015, 10.1016/S0140-6736(14)62449-1.
    • (2015) Lancet
    • Dobson, J.1    Whitley, R.J.2    Pocock, S.3    Monto, A.S.4


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