Application of a hydrogel spacer for postoperative salvage radiotherapy of prostate cancer;Einsatz eines Hydrogel-Abstandhalters bei der postoperativen Salvage-Radiotherapie des Prostatakarzinoms

Strahlentherapie und Onkologie

Volumn 191, Issue 4, 2015, Pages 375-379

  Pinkawa, Michael ^a   Schubert, Carolin ^a   Escobar Corral, Nuria ^a   Holy, Richard ^a   Eble, Michael J ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Intensity modulated radiotherapy; Postoperative radiotherapy; Prostate neoplasm; Spacer gel; Treatment planning

Indexed keywords

HYDROGEL;

ADJUVANT THERAPY; AGED; CASE REPORT; COMPUTER ASSISTED RADIOTHERAPY; DEVICES; HUMAN; HYDROGEL; MALE; MATERIALS TESTING; MINIMAL RESIDUAL DISEASE; POSTOPERATIVE CARE; PROCEDURES; PROSTATIC NEOPLASMS; PROSTHESES AND ORTHOSES; RADIATION DOSE FRACTIONATION; RADIATION PROTECTION; SALVAGE THERAPY; TREATMENT OUTCOME;

AGED; DOSE FRACTIONATION; HUMANS; HYDROGEL; MALE; MATERIALS TESTING; NEOPLASM, RESIDUAL; POSTOPERATIVE CARE; PROSTATIC NEOPLASMS; PROSTHESES AND IMPLANTS; RADIATION PROTECTION; RADIOTHERAPY, ADJUVANT; RADIOTHERAPY, CONFORMAL; SALVAGE THERAPY; TREATMENT OUTCOME;

EID: 84933519180     PISSN: 01797158     EISSN: 1439099X     Source Type: Journal    
DOI: 10.1007/s00066-014-0769-z     Document Type: Article

References (26)

1. Bolla M, Van PH, Tombal B et al (2012) Postoperative radiotherapy after radical prostatectomy for high-risk prostate cancer: long-term results of a randomised controlled trial (EORTC trial 22911). Lancet 380:2018–2027
2. Cozzarini C, Montorsi F, Fiorino C et al (2009) Need for high radiation dose (>or = 70 gy) in early postoperative irradiation after radical prostatectomy: a single-institution analysis of 334 high-risk, node-negative patients. Int J Radiat Oncol Biol Phys 75:966–974
3. Donin NM, Laze J, Zhou M et al (2013) Gleason 6 prostate tumors diagnosed in the PSA era do not demonstrate the capacity for metastatic spread at the time of radical prostatectomy. Urology 82:148–153
4. Eckert F, Alloussi S, Paulsen F et al (2013) Prospective evaluation of a hydrogel spacer for rectal separation in dose-escalated intensity-modulated radiotherapy for clinically localized prostate cancer. BMC Cancer 13:27
5. Ghadjar P, Zwahlen D, Aebersold DM et al (2012) Postoperative radiotherapy after radical prostatectomy: indications and open questions. Prostate Cancer 2012:963417
6. Lohm G, Lutcke J, Jamil B et al. (2014) Salvage radiotherapy in patients with prostate cancer and biochemical relapse after radical prostatectomy: long-term follow-up of a single-center survey. Strahlenther Onkol 190:727-731
7. Melchert C, Gez E, Bohlen G et al. (2013) Interstitial biodegradable balloon for reduced rectal dose during prostate radiotherapy: results of a virtual planning investigation based on the pre- and post-implant imaging data of an international multicenter study. Radiother Oncol 106:210–214
8. Nguyen PL, Devlin PM, Beard CJ et al (2013) High-dose-rate brachytherapy for prostate cancer in a previously radiated patient with polyethylene glycol hydrogel spacing to reduce rectal dose: case report and review of the literature. Brachytherapy 12:77–83
9. Ohri N, Dicker AP, Trabulsi EJ et al (2012) Can early implementation of salvage radiotherapy for prostate cancer improve the therapeutic ratio? A systematic review and regression meta-analysis with radiobiological modelling. Eur J Cancer 48:837–844
10. Pinkawa M, Corral NE, Caffaro M et al (2011) Application of a spacer gel to optimize three-dimensional conformal and intensity modulated radiotherapy for prostate cancer. Radiother Oncol 100:436–441
11. Pinkawa M, Piroth MD, Holy R et al (2011) Combination of dose escalation with technological advances (intensity-modulated and image-guided radiotherapy) is not associated with increased morbidity for patients with prostate cancer. Strahlenther Onkol 187:479–484
12. Pinkawa M, Piroth MD, Holy R et al (2012) Quality of life after intensity-modulated radiotherapy for prostate cancer with a hydrogel spacer. Matched-pair analysis. Strahlenther Onkol 188:917–925
13. Pinkawa M, Piroth MD, Holy R et al (2013) Spacer stability and prostate position variability during radiotherapy for prostate cancer applying a hydrogel to protect the rectal wall. Radiother Oncol 106:220–224
14. Pinkawa M, Bornemann C, Escobar-Corral N et al (2013) Treatment planning shortly after injection of a hydrogel spacer to protect the rectal wall during radiotherapy of prostate cancer. Strahlenther Onkol 189:796–800
15. Pinkawa M, Klotz J, Djukic V et al (2013) Learning curve in the application of a hydrogel spacer to protect the rectal wall during radiotherapy of localized prostate cancer. Urology 82:963–968
16. Poortmans P, Bossi A, Vandeputte K et al (2007) Guidelines for target volume definition in post-operative radiotherapy for prostate cancer, on behalf of the eortc radiation oncology group. Radiother Oncol 84:121–127
17. Prada PJ, Jimenez I, Gonzalez-Suarez H et al (2012) High-dose-rate interstitial brachytherapy as monotherapy in one fraction and transperineal hyaluronic acid injection into the perirectal fat for the treatment of favorable stage prostate cancer: treatment description and preliminary results. Brachytherapy 11:105–110
18. Sanpaolo P, Barbieri V, Genovesi D (2014) Biologically effective dose and definitive radiation treatment for localized prostate cancer: treatment gaps do affect the risk of biochemical failure. Strahlenther Onkol 190:732-738
19. Susil RC, McNutt TR, DeWeese TL et al (2010) Effects of prostate-rectum separation on rectal dose from external beam radiotherapy. Int J Radiat Oncol Biol Phys 76:1251–1258
20. Thompson IM, Tangen CM, Paradelo J et al (2009) Adjuvant radiotherapy for pathological T3N0M0 prostate cancer significantly reduces risk of metastases and improves survival: long-term followup of a randomized clinical trial. J Urol 181:956–962
21. Tselis N, Maurer U, Popp W et al (2014) Evaluation of time, attendance of medical staff, and resources during interstitial brachytherapy for prostate cancer: DEGRO-QUIRO trial. Strahlenther Onkol 190:358–363
22. Uhl M, Herfarth K, Eble MJ et al (2014) Absorbable hydrogel spacer use in men undergoing prostate cancer radiotherapy: 12 months toxicity and proctoscopy results of a prospective multicenter phase II trial. Radiat Oncol 9:96
23. Valicenti RK, Thompson I Jr, Albertsen P et al (2013) Adjuvant and salvage radiation therapy after prostatectomy: American Society for Radiation Oncology/American Urological Association guidelines. Int J Radiat Oncol Biol Phys 86:822–828
24. Viani GA, Stefano EJ, Alfonso SL (2009) Higher-than-conventional radiation doses in localized prostate cancer treatment: a meta-analysis of randomized, controlled trials. Int J Radiat Oncol Biol Phys 74:1405–1418
25. Wenz F, Martin T, Bohmer D et al (2010) The German S3 guideline prostate cancer: aspects for the radiation oncologist. Strahlenther Onkol 186:531–534
26. Wiegel T, Bottke D, Steiner U et al (2009) Phase III postoperative adjuvant radiotherapy after radical prostatectomy compared with radical prostatectomy alone in pT3 prostate cancer with postoperative undetectable prostate-specific antigen: ARO 96–02/AUO AP 09/95. J Clin Oncol 27:2924–2930