Is the monoclonal spread of the ST258, KPC-3-producing clone being replaced in southern Italy by the dissemination of multiple clones of carbapenem-nonsusceptible, KPC-3-producing Klebsiella pneumoniae?

Clinical Microbiology and Infection

Volumn 21, Issue 3, 2015, Pages e15-e17

  Geraci, D M ^a   Bonura, C ^a   Giuffre M ^a   Saporito, L ^a   Graziano, G ^a   Aleo, A ^a   Fasciana, T ^a   Di Bernardo, F ^b   Stampone, T ^c   Palma, D M ^b   Mammina, C ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b ARNAS Civico di Cristina Benfratelli Hospital   (Italy)

^c Laboratory of Microbiology   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; BACTERIAL DNA; BACTERIAL ENZYME; BACTERIAL RNA; CARBAPENEMASE; CEFEPIME; CIPROFLOXACIN; COLISTIN; EXTENDED SPECTRUM BETA LACTAMASE; GENTAMICIN; KLEBSIELLA PNEUMONIAE CARBAPENEMASE; MEROPENEM; QUINOLONE; RNA 16S; RNA METHYLTRANSFERASE; TIGECYCLINE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BETA LACTAMASE; BETA-LACTAMASE KPC-3, KLEBSIELLA PNEUMONIAE; CARBAPENEM DERIVATIVE;

ANTIBIOTIC SENSITIVITY; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BACTERIUM DETECTION; BACTERIUM ISOLATE; BACTERIUM ISOLATION; CLONAL VARIATION; DISEASE SURVEILLANCE; DNA SEQUENCE; ESCHERICHIA COLI; GENETIC RESISTANCE; HEALTH CARE FACILITY; HUMAN; INFECTION CONTROL; INTENSIVE CARE UNIT; ITALY; KLEBSIELLA PNEUMONIAE; LETTER; MOLECULAR CLONING; MOLECULAR TYPING; MULTILOCUS SEQUENCE TYPING; MULTIPLEX POLYMERASE CHAIN REACTION; NEWBORN INTENSIVE CARE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; ST258 GENE; ANTIBIOTIC RESISTANCE; DRUG EFFECTS; GENETICS; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTIONS; MICROBIOLOGY; PHYSIOLOGY;

KLEBSIELLA PNEUMONIAE;

BACTERIAL PROTEINS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CARBAPENEMS; HUMANS; ITALY; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE;

EID: 84933512185     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1016/j.cmi.2014.08.022     Document Type: Letter

References (6)

1. Nordmann P., Poirel L. The difficult-to-control spread of carbapenemase producers among Enterobacteriaceae worldwide. Clin Microbiol Infect 2014, 20:821-830.
2. Munoz-Price L.S., Poirel L., Bonomo R.A., Schwaber M.J., Daikos G.L., Cormican M., et al. Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases. Lancet Infect Dis 2013, 13:785-796.
3. KPC-3 from Klebsiella pneumoniae to Escherichia coli in surgery patients. Clin Microbiol Infect 2014 Jan 30, 10.1111/1469-0691.12577.
4. Hu L., Zhong Q., Shang Y., Wang H., Ning C., Li Y., et al. The prevalence of carbapenemase genes and plasmid-mediated quinolone resistance determinants in carbapenem-resistant Enterobacteriaceae from five teaching hospitals in central China. Epidemiol Infect 2014, 142:1972-1977.
5. Yang J., Ye L., Wang W., Luo Y., Zhang Y., Han L. Diverse prevalence of 16S rRNA methylase genes armA and rmtB amongst clinical multidrug-resistant Escherichia coli and Klebsiella pneumoniae isolates. Int J Antimicrob Agents 2011, 38:348-351.
6. Mammina C., Bonura C., Di Bernardo F., Aleo A., Fasciana T., Sodano C., et al. Ongoing spread of colistin-resistant Klebsiella pneumoniae in different wards of an acute general hospital, Italy, June to December 2011. Euro Surveill 2012, 17(33).