Dexamethasone enhances programmed cell death 1 (PD-1) expression during T cell activation: An insight into the optimum application of glucocorticoids in anti-cancer therapy

BMC Immunology

Volumn 16, Issue 1, 2015, Pages

  Xing, Kailin ^a,b   Gu, Bingxin ^a,b   Zhang, Ping ^a   Wu, Xianghua ^a,b  

^a FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Glucocorticoids; Memory T cells; Na ve T cells; PD 1

Indexed keywords

DEXAMETHASONE; GAMMA INTERFERON; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; INTERLEUKIN 2; MESSENGER RNA; PROGRAMMED DEATH 1 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; ANTINEOPLASTIC AGENT; GLUCOCORTICOID; MIFEPRISTONE; PDCD1 PROTEIN, HUMAN; PDCD1 PROTEIN, MOUSE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG POTENCY; DRUG SENSITIVITY; EC50; FEMALE; HUMAN; HUMAN CELL; LYMPHOCYTE FUNCTION; MEMORY T LYMPHOCYTE; MOUSE; NAIVE T LYMPHOCYTE; NONHUMAN; PROTEIN EXPRESSION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; KINETICS; LYMPHOCYTE ACTIVATION; METABOLISM;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; DEXAMETHASONE; FEMALE; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; KINETICS; LYMPHOCYTE ACTIVATION; MICE, INBRED BALB C; MIFEPRISTONE; PROGRAMMED CELL DEATH 1 RECEPTOR; RNA, MESSENGER; T-LYMPHOCYTES; UP-REGULATION;

EID: 84933507760     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/s12865-015-0103-2     Document Type: Article

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