Selective targeting of bioengineered platelets to prostate cancer vasculature: New paradigm for therapeutic modalities

Journal of Cellular and Molecular Medicine

Volumn 19, Issue 7, 2015, Pages 1530-1537

  Montecinos, Viviana P ^a   Morales, Claudio H ^b,c   Fischer, Thomas H ^d   Burns, Sarah ^b   San Francisco, Ignacio F ^a   Godoy, Alejandro S ^a,b   Smith, Gary J ^b  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

^c HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE   (Chile)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Androgen deprivation; Human prostate xenografts; Platelets; SPIO nanoparticles

Indexed keywords

ANIMALIA;

ANDROGEN;

AGED; ANIMAL; BIOENGINEERING; CELL ADHESION; DRUG EFFECTS; DRUG SCREENING; ENDOTHELIUM CELL; FLUORESCENCE IMAGING; FREEZE DRYING; HUMAN; MALE; METABOLISM; MIDDLE AGED; MOUSE; PATHOLOGY; PROCEDURES; PROSTATE; PROSTATE TUMOR; THROMBOCYTE; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULARIZATION;

AGED; ANDROGENS; ANIMALS; BIOENGINEERING; BLOOD PLATELETS; CELL ADHESION; ENDOTHELIAL CELLS; FREEZE DRYING; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MICE; MIDDLE AGED; OPTICAL IMAGING; PROSTATE; PROSTATIC NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84933278691     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12515     Document Type: Article

References (23)

1. Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med. 1971; 285: 1182-6.
2. Ebos JM, Kerbel RS. Antiangiogenic therapy: impact on invasion, disease progression, and metastasis. Nat Rev Clin Oncol. 2011; 8: 316.
3. Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science. 2005; 307: 58-62.
4. Vartanian RK, Weidner N. Endothelial cell proliferation in prostatic carcinoma and prostatic hyperplasia: correlation with Gleason's score, microvessel density, and epithelial cell proliferation. Lab Invest. 1995; 73: 844-50.
5. Weidner N, Carroll PR, Flax J, et al. Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol. 1993; 143: 401-9.
6. Lissbrant IF, Stattin P, Damber JE, et al. Vascular density is a predictor of cancer-specific survival in prostatic carcinoma. Prostate. 1997; 33: 38-45.
7. Alonzi R, Padhani AR, Taylor NJ, et al. Antivascular effects of neoadjuvant androgen deprivation for prostate cancer: an in vivo human study using susceptibility and relaxivity dynamic MRI. Int J Radiat Oncol Biol Phys. 2011; 80: 721-7.
8. Kravchick S, Cytron S, Mamonov A, et al. Effect of short-term dutasteride therapy on prostate vascularity in patients with benign prostatic hyperplasia: a pilot study. Urology. 2009; 73: 1274-8.
9. Montecinos VP, Godoy A, Hinklin J, et al. Primary xenografts of human prostate tissue as a model to study angiogenesis induced by reactive stroma. PLoS ONE. 2012; 7: e29623.
10. Godoy A, Montecinos VP, Gray DR, et al. Androgen deprivation induces rapid involution and recovery of human prostate vasculature. Am J Physiol Endocrinol Metab. 2011; 300: E263-75.
11. Fischer TH, Bode AP, Parker BR, et al. Primary and secondary hemostatic functionalities of rehydrated, lyophilized platelets. Transfusion. 2006; 46: 1943-50.
12. Read MS, Reddick RL, Bode AP, et al. Preservation of hemostatic and structural properties of rehydrated lyophilized platelets: potential for long-term storage of dried platelets for transfusion. Proc Natl Acad Sci USA. 1995; 92: 397-401.
13. Morrison C, Cheney R, Johnson CS, et al. Central quadrant procurement of radical prostatectomy specimens. Prostate. 2009; 69: 770-3.
14. Gray DR, Huss WJ, Yau JM, et al. Short-term human prostate primary xenografts: an in vivo model of human prostate cancer vasculature and angiogenesis. Cancer Res. 2004; 64: 1712-21.
15. Clement O, Siauve N, Cuenod CA, et al. Liver imaging with ferumoxides (Feridex): fundamentals, controversies, and practical aspects. Top Magn Reson Imaging. 1998; 9: 167-82.
16. Oldenburg AL, Gallippi CM, Tsui F, et al. Magnetic and contrast properties of labeled platelets for magnetomotive optical coherence tomography. Biophys J. 2010; 99: 2374-83.
17. Manodori AB, Matsui NM, Chen JY, et al. Enhanced adherence of sickle erythrocytes to thrombin-treated endothelial cells involves interendothelial cell gap formation. Blood. 1998; 92: 3445-54.
18. Garcia JG. Molecular mechanisms of thrombin-induced human and bovine endothelial cell activation. J Lab Clin Med. 1992; 120: 513-9.
19. Fischer TH, Merricks EP, Russell KE, et al. Intracellular function in rehydrated lyophilized platelets. Br J Haematol. 2000; 111: 167-74.
20. Fischer TH, Merricks EP, Bode AP, et al. Thrombus formation with rehydrated, lyophilized platelets. Hematology. 2002; 7: 359-69.
21. Dvorak HF. Rous-Whipple Award Lecture. How tumors make bad blood vessels and stroma. Am J Pathol. 2003; 162: 1747-57.
22. Bode AP, Fischer TH. Lyophilized platelets: fifty years in the making. Artif Cells Blood Substit Immobil Biotechnol. 2007; 35: 125-33.
23. Fischer TH, Merricks E, Nichols TC, et al. The co-infusion of rehydrated, lyophilized platelets with HBOC-201 for hemostasis in dilutional thrombocytopenia. Blood. 2001; 98: 2250.