Fluorescence in situ hybridization detects increased sperm aneuploidy in men with recurrent pregnancy loss

Fertility and Sterility

Volumn 103, Issue 4, 2015, Pages 906-909.e1

  Ramasamy, Ranjith ^a   Scovell, Jason M ^a   Kovac, Jason R ^a   Cook, Peter J ^a   Lamb, Dolores J ^a   Lipshultz, Larry I ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Aneuploidy; FISH; Genetics; Male infertility

Indexed keywords

ADULT; ANEUPLOIDY; ARTICLE; AUTOSOME; CHROMOSOME 13; CHROMOSOME 18; CHROMOSOME 3; CHROMOSOME ANALYSIS; CONTROLLED STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; RECURRENT PREGNANCY LOSS; SEMEN ANALYSIS; SEX CHROMOSOME ABERRATION; SPERM; SPERM AUTOSOME ANEUPLOIDY; SPERMATOZOON DENSITY; SPERMATOZOON MOTILITY; SPONTANEOUS ABORTION; X CHROMOSOME; Y CHROMOSOME; ABORTION, HABITUAL; CASE CONTROL STUDY; DNA FRAGMENTATION; EMBRYO DEATH; GENETICS; INFERTILITY, MALE; METABOLISM; PATHOLOGY; PREGNANCY; PROCEDURES; RETROSPECTIVE STUDY; SPERMATOZOON; YOUNG ADULT;

ABORTION, HABITUAL; ADULT; ANEUPLOIDY; CASE-CONTROL STUDIES; DNA FRAGMENTATION; EMBRYO LOSS; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFERTILITY, MALE; MALE; PREGNANCY; RETROSPECTIVE STUDIES; SEMEN ANALYSIS; SPERMATOZOA; YOUNG ADULT;

EID: 84933177365     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2015.01.029     Document Type: Article

References (14)

1. Chandra A, Martinez GM, Mosher WD, Abma JC, Jones J. Fertility, family planning, reproductive health U.S women: data from the 2002 National Survey of Family Growth. Vital Health Stat 23 2005;25:1-160.
2. Hansen M, Bower C, Milne E, de Klerk N, Kurinczuk JJ. Assisted reproductive technologies and the risk of birth defects-a systematic review. Hum Reprod 2005;20:328-38.
3. Ludwig M. Risk during pregnancy and birth after assisted reproductive technologies: An integral view of the problem. Semin Reprod Med 2005; 23:363-70.
4. Rimm AA, Katayama AC, Diaz M, Katayama KP. A meta-analysis of controlled studiescomparing major malformation rates in IVF and ICSI infants with naturally conceived children. J Assist Reprod Genet 2004;21:437-43.
5. Sanchez R, Stalf T, Khanaga O, Turley H, Gips H, Schill WB. Sperm selection methods for intracytoplasmic sperm injection (ICSI) in andrological patients. J Assist Reprod Genet 1996;13:228-33.
6. Blanco J, Rubio C, Simon C, Egozcue J, Vidal F. Increased incidence of disomic sperm nuclei in a 47,XYY male assessed by fluorescent in situ hybridization (FISH). Hum Genet 1997;99:413-6.
7. Retief AE, Van Zyl JA, Menkveld R, Fox MF, Kotze GM, Brusnicky J. Chromosome studies in 496 infertile males with a sperm count below 10 million/ml. Hum Genet 1984;66:162-4.
8. Matsuda T, Horii Y, Ogura K, Nonomura M, Okada K, Yoshida O. [Chromosomal survey of 1001 subfertile males: incidence and clinical features of males with chromosomal anomalies]. Hinyokika Kiyo 1992;38:803-9.
9. Rucker GB, Mielnik A, King P, Goldstein M, Schlegel PN. Preoperative screening for genetic abnormalities in men with nonobstructive azoospermia before testicular sperm extraction. J Urol 1998;160:2068-71.
10. Wong EC, Ferguson KA, Chow V, Ma S. Sperm aneuploidy and meiotic sex chromosome configurations in an infertile XYY male. Hum Reprod 2008;23: 374-8.
11. Ferguson KA, Wong EC, Chow V, Nigro M, Ma S. Abnormal meiotic recombination in infertile men and its association with sperm aneuploidy. Hum Mol Genet 2007;16:2870-9.
12. Hotaling J, Carrell DT. Clinical genetic testing for male factor infertility: current applications and future directions. Andrology 2014;2:339-50.
13. Ryu HM, Lin WW, Lamb DJ, Chuang W, Lipshultz LI, Bischoff FZ. Increased chromosome X, Y, and 18 nondisjunction in sperm from infertile patients that were identified as normal by strict morphology: implication for intracytoplasmic sperm injection. Fertil Steril 2001;76:879-83.
14. Vialard F, Bailly M, Bouazzi H, Albert M, Pont JC, Mendes V, et al. The high frequency of sperm aneuploidy in klinefelter patients and in nonobstructive azoospermia is due to meiotic errors in euploid spermatocytes. J Androl 2012;33:1352-9.