Serial expression analysis of breast tumors during neoadjuvant chemotherapy reveals changes in cell cycle and immune pathways associated with recurrence and response

Breast Cancer Research

Volumn 17, Issue 1, 2015, Pages

  Magbanua, Mark Jesus M ^a,b   Wolf, Denise M ^a   Yau, Christina ^a,c,d   Davis, Sarah E ^a,c   Crothers, Julia ^a,b   Au, Alfred ^a,c   Haqq, Christopher M ^b   Livasy, Chad ^e   Rugo, Hope S ^a,b   Esserman, Laura ^a,c   Park, John W ^a,b   van 't Veer, Laura J ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^e UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; ANTINEOPLASTIC AGENT; CYCLIN DEPENDENT KINASE INHIBITOR 2B; CYSTEINE RICH PROTEIN 61; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HLA DQA1 ANTIGEN; KI 67 ANTIGEN; POLO LIKE KINASE 1; TAXANE DERIVATIVE; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR E2F3; TRANSCRIPTION FACTOR FOSB; TRASTUZUMAB; TRANSCRIPTOME; TUMOR MARKER;

ADULT; AGED; AGR2 GENE; AP 1 GENE; ARTICLE; AURKA GENE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER SURVIVAL; CDKN2B GENE; CELL CYCLE; CELL PROLIFERATION; CENPF GENE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYR61 GENE; DOWN REGULATION; DRUG EFFICACY; E2F3 GENE; EIF4EBP1 GENE; EML2 GENE; FEMALE; FOSB GENE; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC ASSOCIATION; HLA DOA GENE; HLA DQA1 GENE; HUMAN; HUMAN TISSUE; IFI44L GENE; IFIH1 GENE; IFIT1 GENE; IFIT2 GENE; IFITM1 GENE; INTRACELLULAR SIGNALING; JUN GENE; MAJOR CLINICAL STUDY; MAP3K14 GENE; MASTECTOMY; MICROARRAY ANALYSIS; MULTIPLE CYCLE TREATMENT; OUTCOME ASSESSMENT; PLK1 GENE; PREDICTIVE VALUE; PROTEIN EXPRESSION; RECURRENCE FREE SURVIVAL; SMARCB1 GENE; TGFBI GENE; TLR7 GENE; TLR8 GENE; TUMOR BIOPSY; TUMOR IMMUNITY; UPREGULATION; BREAST NEOPLASMS; CANCER GRADING; CANCER STAGING; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MIDDLE AGED; MORTALITY; NEOADJUVANT THERAPY; PATHOLOGY; PROGNOSIS; SIGNAL TRANSDUCTION; TIME FACTOR; TREATMENT OUTCOME; TUMOR RECURRENCE; TUMOR VOLUME;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BIOMARKERS, TUMOR; BREAST NEOPLASMS; CELL CYCLE; CLUSTER ANALYSIS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; KI-67 ANTIGEN; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM GRADING; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROGNOSIS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTOME; TREATMENT OUTCOME; TUMOR BURDEN;

EID: 84932643128     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/s13058-015-0582-3     Document Type: Article

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