A non-chromatographic method for the removal of endotoxins from bacteriophages

Biotechnology and Bioengineering

Volumn 112, Issue 8, 2015, Pages 1714-1719

  Branston, Steven D ^a   Wright, Jason ^b   Keshavarz Moore, Eli ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NeuroPhage Pharmaceuticals   (United States)

Author keywords

Bacteriophage; Bioprocessing; Detergent; Endotoxin; Precipitation; Purification

Indexed keywords

BACTERIA; BACTERIOPHAGES; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; DETERGENTS; ESCHERICHIA COLI; LIGHT SCATTERING; MOLECULES; PROTEINS; PURIFICATION; SCALABILITY; SEPARATION;

ANION EXCHANGE CHROMATOGRAPHY; BIOPROCESSING; CHROMATOGRAPHIC METHODS; ENDOTOXIN; EXTRACELLULAR SPACE; GRAM-NEGATIVE BACTERIA; HUMAN THERAPEUTICS; PHARMACEUTICAL APPLICATIONS;

PRECIPITATION (CHEMICAL);

ESCHERICHIA COLI ENDOTOXIN; MACROGOL; SODIUM CHLORIDE; TRITON X 100; TRITON X 114; ENDOTOXIN; MACROGOL 6000; MACROGOL DERIVATIVE; OCTOXINOL;

AQUEOUS SOLUTION; ARTICLE; BACTERIUM CONTAMINATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DYNAMIC LIGHT SCATTERING; ENTEROBACTERIA PHAGE M13; INVESTIGATIVE PROCEDURES; NONHUMAN; PARTICLE SIZE; PHASE SEPARATION; PRECIPITATION; PURIFICATION; BACTERIOPHAGE; CHEMISTRY; FRACTIONATION; ISOLATION AND PURIFICATION; PHARMACEUTICS; PROCEDURES;

FILAMENTOUS BACTERIOPHAGE; NEGIBACTERIA;

BACTERIOPHAGES; CHEMICAL FRACTIONATION; CHEMICAL PRECIPITATION; ENDOTOXINS; OCTOXYNOL; POLYETHYLENE GLYCOLS; SODIUM CHLORIDE; TECHNOLOGY, PHARMACEUTICAL;

EID: 84932198792     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25571     Document Type: Article

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