Clarithromycin versus metronidazole as first-line helicobacter pylori eradication

Journal of Clinical Gastroenterology

Volumn 49, Issue 6, 2015, Pages 468-471

  Nishizawa, Toshihiro ^a,b   Maekawa, Takama ^d   Watanabe, Noriko ^e   Harada, Naohiko ^f   Hosoda, Yasuo ^g   Yoshinaga, Masahiro ^h   Yoshio, Toshiyuki ⁱ   Ohta, Hajime ^k   Inoue, Syuuji ^p   Toyokawa, Tatsuya ^l   Yamashita, Haruhiro ⁱ   Saito, Hiroki ^m   Kuwai, Toshio ⁱ   Katayama, Shunsuke ^o   Masuda, Eiji ^j   Miyabayashi, Hideharu ^q   Kimura, Toshio ⁿ   Nishizawa, Yuko ^c   Takahashi, Masahiko ^a   Suzuki, Hidekazu ^b  

^a NATIONAL HOSPITAL ORGANIZATION TOKYO MEDICAL CENTER   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^d NATIONAL HOSPITAL ORGANIZATION KYOTO MEDICAL CENTER   (Japan)

^e National Hospital Organization Mie Chuo Medical Center   (Japan)

^f NATIONAL HOSPITAL ORGANIZATION KYUSHU MEDICAL CENTER   (Japan)

^g SAITAMA NATIONAL HOSPITAL   (Japan)

^h NATIONAL HOSPITAL ORGANIZATION BEPPU MEDICAL CENTER   (Japan)

ⁱ NATIONAL HOSPITAL ORGANIZATION   (Japan)

^j MINAMI OSAKA GENERAL HOSPITAL   (Japan)

^k NATIONAL HOSPITAL ORGANIZATION KANAZAWA MEDICAL CENTER   (Japan)

^l NATIONAL HOSPITAL ORGANIZATION FUKUYAMA MEDICAL CENTER   (Japan)

^m National Hospital Organization Asahikawa Medical Center   (Japan)

ⁿ HOKKAIDO MEDICAL CENTER   (Japan)

^o National Hospital Organisation Yonago Medical Center   (Japan)

^p National Hospital Organization Kochi National Hospital   (India)

^q National Hospital Organization Matsumoto Medical Center Matsumoto Hospital   (Japan)

more..

Author keywords

clarithromycin; eradication; Helicobacter pylori; metronidazole

Indexed keywords

AMOXICILLIN; CLARITHROMYCIN; METRONIDAZOLE; RABEPRAZOLE; UREA C 13; ANTIINFECTIVE AGENT; ANTIULCER AGENT; UREA;

ADULT; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; ATROPHIC GASTRITIS; BACTERIAL CLEARANCE; COMPARATIVE STUDY; CONTROLLED STUDY; DIARRHEA; DRUG EFFICACY; DRUG ERUPTION; DRUG TOLERABILITY; FEMALE; HELICOBACTER PYLORI; HUMAN; JAPAN; LIVER DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MEDICATION COMPLIANCE; MULTICENTER STUDY; NAUSEA; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TASTE DISORDER; UREA BREATH TEST; AGED; BREATH ANALYSIS; CLINICAL TRIAL; COMBINATION DRUG THERAPY; DRUG EFFECTS; HELICOBACTER INFECTIONS; MIDDLE AGED;

AGED; AMOXICILLIN; ANTI-INFECTIVE AGENTS; ANTI-ULCER AGENTS; BREATH TESTS; CLARITHROMYCIN; DRUG RESISTANCE, BACTERIAL; DRUG THERAPY, COMBINATION; FEMALE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; JAPAN; MALE; METRONIDAZOLE; MIDDLE AGED; PROSPECTIVE STUDIES; RABEPRAZOLE; UREA;

EID: 84932193569     PISSN: 01920790     EISSN: 15392031     Source Type: Journal    
DOI: 10.1097/MCG.0000000000000165     Document Type: Article

References (18)

1. Fukase K, Kato M, Kikuchi S, et al. Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial. Lancet. 2008; 372: 392-397
2. Nishizawa T, Suzuki H, Nakagawa I, et al. Early Helicobacter pylori eradication restores sonic hedgehog expression in the gastric mucosa of Mongolian gerbils. Digestion. 2009; 79: 99-108
3. Suzuki H, Nishizawa T, Tsugawa H, et al. Molecular approaches and modern clinical strategies for the management of Helicobacter pylori infection in Japan. Keio J Med. 2012; 61: 109-119
4. Nishizawa T, Suzuki H. The role of microRNA in gastric malignancy. Int J Mol Sci. 2013; 14: 9487-9496
5. Suzuki H, Nishizawa T, Hibi T. Helicobacter pylori eradication therapy. Future Microbiol. 2010; 5: 639-648
6. Asaka M, Kato M, Takahashi S, et al. Guidelines for the management of Helicobacter pylori infection in Japan: 2009 revised edition. Helicobacter. 2010; 15: 1-20
7. Asaoka D, Nagahara A, Matsuhisa T, et al. Trends of secondline eradication therapy for Helicobacter pylori in Japan: a multicenter study in the Tokyo metropolitan area. Helicobacter. 2013; 18: 468-472
8. Nishizawa T, Suzuki H, Takahashi M, et al. Delay of secondline eradication therapy for Helicobacter pylori can increase eradication failure. J Gastroenterol Hepatol. 2013; 28: 1608-1610
9. Nishizawa T, Suzuki H, Suzuki M, et al. Proton pump inhibitor-Amoxicillin-clarithromycin versus proton pump inhibitor-Amoxicillin-metronidazole as first-line Helicobacter pylori eradication therapy. J Clin Biochem Nutr. 2012; 51: 114-116
10. Nishizawa T, Suzuki H, Maekawa T, et al. Dual therapy for third-line Helicobacter pylori eradication and urea breath test prediction. World J Gastroenterol. 2012; 18: 2735-2738
11. Nishizawa T, Suzuki H, Matsuzaki J, et al. Helicobacter pylori resistance to rifabutin in the last 7 years. Antimicrob Agents Chemother. 2011; 55: 5374-5375
12. Hirata K, Suzuki H, Nishizawa T, et al. Contribution of efflux pumps to clarithromycin resistance in Helicobacter pylori. J Gastroenterol Hepatol. 2010; 25(suppl 1): S75-S79
13. Nishizawa T, Suzuki H, Masaoka T, et al A new eradication resistance index as a predictor of metronidazole-containing second-line treatment of Helicobacter pylori. Digestion. 2007; 76: 215-220
14. Nishizawa T, Suzuki H, Nakagawa I, et al. Gatifloxacin-based triple therapy as a third-line regimen for Helicobacter pylori eradication. J Gastroenterol Hepatol. 2008; 23(suppl 2): S167-S170
15. Murakami K, Furuta T, Ando T, et al. Multi-center randomized controlled study to establish the standard thirdline regimen for Helicobacter pylori eradication in Japan. J Gastroenterol. 2013; 48: 1128-1135
16. Fock KM, Katelaris P, Sugano K, et al. Second Asia-Pacific Consensus Guidelines for Helicobacter pylori infection. J Gastroenterol Hepatol. 2009; 24: 1587-1600
17. Sasaki M, Ogasawara N, Utsumi K, et al. Changes in 12-year first-line eradication rate of Helicobacter pylori based on triple therapy with proton pump inhibitor, amoxicillin and clarithromycin. J Clin Biochem Nutr. 2010; 47: 53-58
18. Nishizawa T, Suzuki H, Tsugawa H, et al. Enhancement of amoxicillin resistance after unsuccessful Helicobacter pylori eradication. Antimicrob Agents Chemother. 2011; 55: 3012-3014