메뉴 건너뛰기




Volumn 52, Issue 1, 2015, Pages 139-142

Metformin increases peroxisome proliferator-activated receptor γ Co-activator-1α and utrophin a expression in dystrophic skeletal muscle

Author keywords

AMPK; mdx mice; Metformin; PGC 1 ; Utrophin A

Indexed keywords

DYSTROPHIN; METFORMIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; RECEPTOR INTERACTING PROTEIN 140; UNCLASSIFIED DRUG; UTROPHIN; UTROPHIN A; ANTIDIABETIC AGENT; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 84931563123     PISSN: 0148639X     EISSN: 10974598     Source Type: Journal    
DOI: 10.1002/mus.24692     Document Type: Article
Times cited : (51)

References (16)
  • 1
    • 84897064754 scopus 로고    scopus 로고
    • The therapeutic potential of skeletal muscle plasticity in DMD: phenotypic modifiers as pharmacologic targets
    • Ljubicic V, Burt M, Jasmin BJ. The therapeutic potential of skeletal muscle plasticity in DMD: phenotypic modifiers as pharmacologic targets. FASEB J 2014;28:548-568.
    • (2014) FASEB J , vol.28 , pp. 548-568
    • Ljubicic, V.1    Burt, M.2    Jasmin, B.J.3
  • 2
    • 84884813468 scopus 로고    scopus 로고
    • AMP-activated protein kinase at the nexus of therapeutic skeletal muscle plasticity in Duchenne muscular dystrophy
    • Ljubicic V, Jasmin BJ. AMP-activated protein kinase at the nexus of therapeutic skeletal muscle plasticity in Duchenne muscular dystrophy. Trends Mol Med 2013;19:614-624.
    • (2013) Trends Mol Med , vol.19 , pp. 614-624
    • Ljubicic, V.1    Jasmin, B.J.2
  • 3
    • 84903625199 scopus 로고    scopus 로고
    • Resveratrol induces expression of the slow, oxidative phenotype in mdx mouse muscle together with enhanced activity of the SIRT1-PGC-1α axis
    • Ljubicic V, Burt M, Lunde JA, Jasmin BJ. Resveratrol induces expression of the slow, oxidative phenotype in mdx mouse muscle together with enhanced activity of the SIRT1-PGC-1α axis. Am J Physiol Cell Physiol 2014;307:C66-82.
    • (2014) Am J Physiol Cell Physiol , vol.307 , pp. C66-C82
    • Ljubicic, V.1    Burt, M.2    Lunde, J.A.3    Jasmin, B.J.4
  • 4
    • 84924455400 scopus 로고    scopus 로고
    • Utrophin A is essential in mediating the functional adaptations of mdx mouse muscle following chronic AMPK activation
    • Al-Rewashdy H, Ljubicic V, Lin W, Renaud JM, Jasmin BJ. Utrophin A is essential in mediating the functional adaptations of mdx mouse muscle following chronic AMPK activation. Hum Mol Genet 2015;24:1243-1255.
    • (2015) Hum Mol Genet , vol.24 , pp. 1243-1255
    • Al-Rewashdy, H.1    Ljubicic, V.2    Lin, W.3    Renaud, J.M.4    Jasmin, B.J.5
  • 5
    • 33845411854 scopus 로고    scopus 로고
    • Metformin increases the PGC-1alpha protein and oxidative enzyme activities possibly via AMPK phosphorylation in skeletal muscle in vivo
    • 1985
    • Suwa M, Egashira T, Nakano H, Sasaki H, Kumagai S. Metformin increases the PGC-1alpha protein and oxidative enzyme activities possibly via AMPK phosphorylation in skeletal muscle in vivo. J Appl Physiol (1985) 2006;101:1685-1692.
    • (2006) J Appl Physiol , vol.101 , pp. 1685-1692
    • Suwa, M.1    Egashira, T.2    Nakano, H.3    Sasaki, H.4    Kumagai, S.5
  • 6
    • 84900563749 scopus 로고    scopus 로고
    • Two weeks of metformin treatment induces AMPK-dependent enhancement of insulin-stimulated glucose uptake in mouse soleus muscle
    • Kristensen JM, Treebak JT, Schjerling P, Goodyear L, Wojtaszewski JF. Two weeks of metformin treatment induces AMPK-dependent enhancement of insulin-stimulated glucose uptake in mouse soleus muscle. Am J Physiol Endocrinol Metab 2014;306:E1099-1109.
    • (2014) Am J Physiol Endocrinol Metab , vol.306 , pp. E1099-E1109
    • Kristensen, J.M.1    Treebak, J.T.2    Schjerling, P.3    Goodyear, L.4    Wojtaszewski, J.F.5
  • 7
    • 77954434212 scopus 로고    scopus 로고
    • Metformin therapy to reduce weight gain and visceral adiposity in children and adolescents with neurogenic or myogenic motor deficit
    • Casteels K, Fieuws S, van Helvoirt M, Verpoorten C, Goemans N, Coudyzer W, et al. Metformin therapy to reduce weight gain and visceral adiposity in children and adolescents with neurogenic or myogenic motor deficit. Pediatr Diabetes 2010;11:61-69.
    • (2010) Pediatr Diabetes , vol.11 , pp. 61-69
    • Casteels, K.1    Fieuws, S.2    van Helvoirt, M.3    Verpoorten, C.4    Goemans, N.5    Coudyzer, W.6
  • 8
    • 84931562164 scopus 로고    scopus 로고
    • Metformin improves weight gain and body mass index in Duchenne muscular dystrophy
    • Rutter MM, Wong, BL, Rose SR, Klein DJ. Metformin improves weight gain and body mass index in Duchenne muscular dystrophy. Neuromuscul Disord 2009;19:612.
    • (2009) Neuromuscul Disord , vol.19 , pp. 612
    • Rutter, M.M.1    Wong, B.L.2    Rose, S.R.3    Klein, D.J.4
  • 9
    • 84931574099 scopus 로고    scopus 로고
    • Metformin reduces weight and BMI in Duchenne muscular dystrophy patients on long term glucocorticoid therapy
    • Weatherspoon SE, Collins J, Sucharew H, Wong BL, Rybalsky I, Rose SR, et al. Metformin reduces weight and BMI in Duchenne muscular dystrophy patients on long term glucocorticoid therapy. Neuromuscul Disord 2012;22:866.
    • (2012) Neuromuscul Disord , vol.22 , pp. 866
    • Weatherspoon, S.E.1    Collins, J.2    Sucharew, H.3    Wong, B.L.4    Rybalsky, I.5    Rose, S.R.6
  • 11
    • 84931588189 scopus 로고    scopus 로고
    • L-citrulline and metformin in Duchenne's muscular dystrophy.Accessed February 8
    • Bonati U, Fischer D. L-citrulline and metformin in Duchenne's muscular dystrophy. https://clinicaltrials.gov/ct2/show/NCT01995032?term=01995032&rank=1. Accessed February 8, 2015.
    • (2015)
    • Bonati, U.1    Fischer, D.2
  • 13
    • 80051692198 scopus 로고    scopus 로고
    • Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscle
    • Ljubicic V, Miura P, Burt M, Boudreault L, Khogali S, Lunde JA, et al. Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscle. Hum Mol Genet 2011;20:3478-3493.
    • (2011) Hum Mol Genet , vol.20 , pp. 3478-3493
    • Ljubicic, V.1    Miura, P.2    Burt, M.3    Boudreault, L.4    Khogali, S.5    Lunde, J.A.6
  • 14
    • 83455250428 scopus 로고    scopus 로고
    • Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle
    • Ljubicic V, Khogali S, Renaud JM, Jasmin BJ. Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle. Am J Physiol Cell Physiol 2012;302:C110-121.
    • (2012) Am J Physiol Cell Physiol , vol.302 , pp. C110-C121
    • Ljubicic, V.1    Khogali, S.2    Renaud, J.M.3    Jasmin, B.J.4
  • 15
    • 44449103256 scopus 로고    scopus 로고
    • Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
    • Huang X, Wullschleger S, Shapiro N, McGuire VA, Sakamoto K, Woods YL, et al. Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice. Biochem J 2008;412:211-221.
    • (2008) Biochem J , vol.412 , pp. 211-221
    • Huang, X.1    Wullschleger, S.2    Shapiro, N.3    McGuire, V.A.4    Sakamoto, K.5    Woods, Y.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.