-
1
-
-
67650141987
-
Non mycobacterial virulence genes in the genome of the emerging pathogen Mycobacterium abscessus
-
F. Ripoll, S. Pasek, C. Schenowitz, C. Dossat, V. Barbe, M. Rottman, E. Macheras, B. Heym, J.L. Herrmann, M. Daffe, R. Brosch, J.L. Risler, and J.L. Gaillard Non mycobacterial virulence genes in the genome of the emerging pathogen Mycobacterium abscessus PLoS One 4 2009 e5660
-
(2009)
PLoS One
, vol.4
, pp. e5660
-
-
Ripoll, F.1
Pasek, S.2
Schenowitz, C.3
Dossat, C.4
Barbe, V.5
Rottman, M.6
MacHeras, E.7
Heym, B.8
Herrmann, J.L.9
Daffe, M.10
Brosch, R.11
Risler, J.L.12
Gaillard, J.L.13
-
2
-
-
84887065850
-
Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistent Mycobacterium abscessus
-
A. Pawlik, G. Garnier, M. Orgeur, P. Tong, A.J. Lohan, F. LeChevalier, G. Sapriel, A.L. Roux, K. Conlon, N. Honoré, M.A. Dillies, L. Ma, C. Bouchier, J.Y. Coppée, J.L. Gaillard, S.V. Gordon, B. Loftus, R. Brosch, and J.L. Herrmann Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistent Mycobacterium abscessus Mol Microbiol 90 2013 612 629
-
(2013)
Mol Microbiol
, vol.90
, pp. 612-629
-
-
Pawlik, A.1
Garnier, G.2
Orgeur, M.3
Tong, P.4
Lohan, A.J.5
Lechevalier, F.6
Sapriel, G.7
Roux, A.L.8
Conlon, K.9
Honoré, N.10
Dillies, M.A.11
Ma, L.12
Bouchier, C.13
Coppée, J.Y.14
Gaillard, J.L.15
Gordon, S.V.16
Loftus, B.17
Brosch, R.18
Herrmann, J.L.19
-
3
-
-
0030046515
-
Two-laboratory collaborative study on identification of mycobacteria: Molecular versus phenotypic methods
-
B. Springer, L. Stockman, K. Teschner, G.D. Roberts, and E.C. Bottger Two-laboratory collaborative study on identification of mycobacteria: molecular versus phenotypic methods J Clin Microbiol 34 1996 296 303
-
(1996)
J Clin Microbiol
, vol.34
, pp. 296-303
-
-
Springer, B.1
Stockman, L.2
Teschner, K.3
Roberts, G.D.4
Bottger, E.C.5
-
4
-
-
0035931926
-
Massive gene decay in the leprosy bacillus
-
S.T. Cole, K. Eiglmeier, J. Parkhill, K.D. James, N.R. Thomson, P.R. Wheeler, N. Honore, T. Garnier, C. Churcher, D. Harris, K. Mungall, D. Basham, D. Brown, T. Chillingworth, R. Connor, R.M. Davies, K. Devlin, S. Duthoy, T. Feltwell, A. Fraser, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, C. Lacroix, J. Maclean, S. Moule, L. Murphy, K. Oliver, M.A. Quail, M.A. Rajandream, K.M. Rutherford, S. Rutter, K. Seeger, S. Simon, M. Simmonds, J. Skelton, R. Squares, S. Squares, K. Stevens, K. Taylor, S. Whitehead, J.R. Woodward, and B.G. Barrell Massive gene decay in the leprosy bacillus Nature 409 2001 1007 1011
-
(2001)
Nature
, vol.409
, pp. 1007-1011
-
-
Cole, S.T.1
Eiglmeier, K.2
Parkhill, J.3
James, K.D.4
Thomson, N.R.5
Wheeler, P.R.6
Honore, N.7
Garnier, T.8
Churcher, C.9
Harris, D.10
Mungall, K.11
Basham, D.12
Brown, D.13
Chillingworth, T.14
Connor, R.15
Davies, R.M.16
Devlin, K.17
Duthoy, S.18
Feltwell, T.19
Fraser, A.20
Hamlin, N.21
Holroyd, S.22
Hornsby, T.23
Jagels, K.24
Lacroix, C.25
MacLean, J.26
Moule, S.27
Murphy, L.28
Oliver, K.29
Quail, M.A.30
Rajandream, M.A.31
Rutherford, K.M.32
Rutter, S.33
Seeger, K.34
Simon, S.35
Simmonds, M.36
Skelton, J.37
Squares, R.38
Squares, S.39
Stevens, K.40
Taylor, K.41
Whitehead, S.42
Woodward, J.R.43
Barrell, B.G.44
more..
-
5
-
-
0032508046
-
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
-
S.T. Cole, R. Brosch, J. Parkhill, T. Garnier, C. Churcher, D. Harris, S.V. Gordon, K. Eiglmeier, S. Gas, C.E. Barry 3rd, F. Tekaia, K. Badcock, D. Basham, D. Brown, T. Chillingworth, R. Connor, R. Davies, K. Devlin, T. Feltwell, S. Gentles, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, A. Krogh, J. McLean, S. Moule, L. Murphy, K. Oliver, J. Osborne, M.A. Quail, M.A. Rajandream, J. Rogers, S. Rutter, K. Seeger, J. Skelton, R. Squares, S. Squares, J.E. Sulston, K. Taylor, S. Whitehead, and B.G. Barrell Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence Nature 393 1998 537 544
-
(1998)
Nature
, vol.393
, pp. 537-544
-
-
Cole, S.T.1
Brosch, R.2
Parkhill, J.3
Garnier, T.4
Churcher, C.5
Harris, D.6
Gordon, S.V.7
Eiglmeier, K.8
Gas, S.9
Barry, C.E.10
Tekaia, F.11
Badcock, K.12
Basham, D.13
Brown, D.14
Chillingworth, T.15
Connor, R.16
Davies, R.17
Devlin, K.18
Feltwell, T.19
Gentles, S.20
Hamlin, N.21
Holroyd, S.22
Hornsby, T.23
Jagels, K.24
Krogh, A.25
McLean, J.26
Moule, S.27
Murphy, L.28
Oliver, K.29
Osborne, J.30
Quail, M.A.31
Rajandream, M.A.32
Rogers, J.33
Rutter, S.34
Seeger, K.35
Skelton, J.36
Squares, R.37
Squares, S.38
Sulston, J.E.39
Taylor, K.40
Whitehead, S.41
Barrell, B.G.42
more..
-
6
-
-
65449136792
-
Pathogenicity in the tubercle bacillus: Molecular and evolutionary determinants
-
S.V. Gordon, D. Bottai, R. Simeone, T.P. Stinear, and R. Brosch Pathogenicity in the tubercle bacillus: molecular and evolutionary determinants Bioessays 31 2009 378 388
-
(2009)
Bioessays
, vol.31
, pp. 378-388
-
-
Gordon, S.V.1
Bottai, D.2
Simeone, R.3
Stinear, T.P.4
Brosch, R.5
-
7
-
-
49449107199
-
Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state
-
B. Zuber, M. Chami, C. Houssin, J. Dubochet, G. Griffiths, and M. Daffe Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state J Bacteriol 190 2008 5672 5680
-
(2008)
J Bacteriol
, vol.190
, pp. 5672-5680
-
-
Zuber, B.1
Chami, M.2
Houssin, C.3
Dubochet, J.4
Griffiths, G.5
Daffe, M.6
-
8
-
-
41649116701
-
Disclosure of the mycobacterial outer membrane: Cryo-electron tomography and vitreous sections reveal the lipid bilayer structure
-
C. Hoffmann, A. Leis, M. Niederweis, J.M. Plitzko, and H. Engelhardt Disclosure of the mycobacterial outer membrane: cryo-electron tomography and vitreous sections reveal the lipid bilayer structure Proc Natl Acad Sci U S A 105 2008 3963 3967
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 3963-3967
-
-
Hoffmann, C.1
Leis, A.2
Niederweis, M.3
Plitzko, J.M.4
Engelhardt, H.5
-
9
-
-
77950418216
-
Direct visualization by cryo-EM of the mycobacterial capsular layer: A labile structure containing ESX-1-secreted proteins
-
M. Sani, E.N. Houben, J. Geurtsen, J. Pierson, K. de Punder, M. van Zon, B. Wever, S.R. Piersma, C.R. Jimenez, M. Daffe, B.J. Appelmelk, W. Bitter, N. van der Wel, and P.J. Peters Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins PLoS Pathog 6 2010 e1000794
-
(2010)
PLoS Pathog
, vol.6
, pp. e1000794
-
-
Sani, M.1
Houben, E.N.2
Geurtsen, J.3
Pierson, J.4
De Punder, K.5
Van Zon, M.6
Wever, B.7
Piersma, S.R.8
Jimenez, C.R.9
Daffe, M.10
Appelmelk, B.J.11
Bitter, W.12
Van Der Wel, N.13
Peters, P.J.14
-
10
-
-
0037673252
-
SecA2 functions in the secretion of superoxide dismutase A and in the virulence of Mycobacterium tuberculosis
-
M. Braunstein, B.J. Espinosa, J. Chan, J.T. Belisle, and W.R. Jacobs Jr. SecA2 functions in the secretion of superoxide dismutase A and in the virulence of Mycobacterium tuberculosis Mol Microbiol 48 2003 453 464
-
(2003)
Mol Microbiol
, vol.48
, pp. 453-464
-
-
Braunstein, M.1
Espinosa, B.J.2
Chan, J.3
Belisle, J.T.4
Jacobs, Jr.W.R.5
-
11
-
-
27744493918
-
The twin-arginine translocation pathway of Mycobacterium smegmatis is functional and required for the export of mycobacterial beta-lactamases
-
J.A. McDonough, K.E. Hacker, A.R. Flores, M.S. Pavelka Jr., and M. Braunstein The twin-arginine translocation pathway of Mycobacterium smegmatis is functional and required for the export of mycobacterial beta-lactamases J Bacteriol 187 2005 7667 7679
-
(2005)
J Bacteriol
, vol.187
, pp. 7667-7679
-
-
McDonough, J.A.1
Hacker, K.E.2
Flores, A.R.3
Pavelka, Jr.M.S.4
Braunstein, M.5
-
12
-
-
33748765246
-
Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence
-
B. Saint-Joanis, C. Demangel, M. Jackson, P. Brodin, L. Marsollier, H. Boshoff, and S.T. Cole Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence J Bacteriol 188 2006 6669 6679
-
(2006)
J Bacteriol
, vol.188
, pp. 6669-6679
-
-
Saint-Joanis, B.1
Demangel, C.2
Jackson, M.3
Brodin, P.4
Marsollier, L.5
Boshoff, H.6
Cole, S.T.7
-
13
-
-
0345701347
-
Genes required for mycobacterial growth defined by high density mutagenesis
-
C.M. Sassetti, D.H. Boyd, and E.J. Rubin Genes required for mycobacterial growth defined by high density mutagenesis Mol Microbiol 48 2003 77 84
-
(2003)
Mol Microbiol
, vol.48
, pp. 77-84
-
-
Sassetti, C.M.1
Boyd, D.H.2
Rubin, E.J.3
-
14
-
-
80053459692
-
High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism
-
J.E. Griffin, J.D. Gawronski, M.A. Dejesus, T.R. Ioerger, B.J. Akerley, and C.M. Sassetti High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism PLoS Pathog 7 2011 e1002251
-
(2011)
PLoS Pathog
, vol.7
, pp. e1002251
-
-
Griffin, J.E.1
Gawronski, J.D.2
Dejesus, M.A.3
Ioerger, T.R.4
Akerley, B.J.5
Sassetti, C.M.6
-
15
-
-
0036568776
-
The ESAT-6/WXG100 superfamily - And a new Gram-positive secretion system?
-
M.J. Pallen The ESAT-6/WXG100 superfamily - and a new Gram-positive secretion system? Trends Microbiol 10 2002 209 212
-
(2002)
Trends Microbiol
, vol.10
, pp. 209-212
-
-
Pallen, M.J.1
-
16
-
-
5644281780
-
ESAT-6 proteins: Protective antigens and virulence factors?
-
P. Brodin, I. Rosenkrands, P. Andersen, S.T. Cole, and R. Brosch ESAT-6 proteins: protective antigens and virulence factors? Trends Microbiol 12 2004 500 508
-
(2004)
Trends Microbiol
, vol.12
, pp. 500-508
-
-
Brodin, P.1
Rosenkrands, I.2
Andersen, P.3
Cole, S.T.4
Brosch, R.5
-
17
-
-
0028966384
-
Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis
-
A.L. Sorensen, S. Nagai, G. Houen, P. Andersen, and A.B. Andersen Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis Infect Immun 63 1995 1710 1717
-
(1995)
Infect Immun
, vol.63
, pp. 1710-1717
-
-
Sorensen, A.L.1
Nagai, S.2
Houen, G.3
Andersen, P.4
Andersen, A.B.5
-
18
-
-
35348892037
-
Type VII secretion-mycobacteria show the way
-
A. Abdallah, N. Gey van Pittius, P. Champion, J. Cox, J. Luirink, C. Vandenbroucke-Grauls, B. Appelmelk, and W. Bitter Type VII secretion-mycobacteria show the way Nat Rev Microbiol 5 2007 883 891
-
(2007)
Nat Rev Microbiol
, vol.5
, pp. 883-891
-
-
Abdallah, A.1
Gey Van Pittius, N.2
Champion, P.3
Cox, J.4
Luirink, J.5
Vandenbroucke-Grauls, C.6
Appelmelk, B.7
Bitter, W.8
-
19
-
-
0031767535
-
A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CFP-10)
-
F.X. Berthet, P.B. Rasmussen, I. Rosenkrandt, P. Andersen, and B. Gicquel A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CFP-10) Microbiology 144 1998 3195 3203
-
(1998)
Microbiology
, vol.144
, pp. 3195-3203
-
-
Berthet, F.X.1
Rasmussen, P.B.2
Rosenkrandt, I.3
Andersen, P.4
Gicquel, B.5
-
20
-
-
0029920827
-
Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis
-
G.G. Mahairas, P.J. Sabo, M.J. Hickey, D.C. Singh, and C.K. Stover Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis J Bacteriol 178 1996 1274 1282
-
(1996)
J Bacteriol
, vol.178
, pp. 1274-1282
-
-
Mahairas, G.G.1
Sabo, P.J.2
Hickey, M.J.3
Singh, D.C.4
Stover, C.K.5
-
21
-
-
0033612136
-
Comparative genomics of BCG vaccines by whole-genome DNA microarrays
-
M.A. Behr, M.A. Wilson, W.P. Gill, H. Salamon, G.K. Schoolnik, S. Rane, and P.M. Small Comparative genomics of BCG vaccines by whole-genome DNA microarrays Science 284 1999 1520 1523
-
(1999)
Science
, vol.284
, pp. 1520-1523
-
-
Behr, M.A.1
Wilson, M.A.2
Gill, W.P.3
Salamon, H.4
Schoolnik, G.K.5
Rane, S.6
Small, P.M.7
-
22
-
-
0032949025
-
Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays
-
S.V. Gordon, R. Brosch, A. Billault, T. Garnier, K. Eiglmeier, and S.T. Cole Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays Mol Microbiol 32 1999 643 656
-
(1999)
Mol Microbiol
, vol.32
, pp. 643-656
-
-
Gordon, S.V.1
Brosch, R.2
Billault, A.3
Garnier, T.4
Eiglmeier, K.5
Cole, S.T.6
-
23
-
-
0030025636
-
Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG
-
M. Harboe, T. Oettinger, H.G. Wiker, I. Rosenkrands, and P. Andersen Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG Infect Immun 64 1996 16 22
-
(1996)
Infect Immun
, vol.64
, pp. 16-22
-
-
Harboe, M.1
Oettinger, T.2
Wiker, H.G.3
Rosenkrands, I.4
Andersen, P.5
-
24
-
-
0036786509
-
Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant
-
P. Brodin, K. Eiglmeier, M. Marmiesse, A. Billault, T. Garnier, S. Niemann, S.T. Cole, and R. Brosch Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant Infect Immun 70 2002 5568 5578
-
(2002)
Infect Immun
, vol.70
, pp. 5568-5578
-
-
Brodin, P.1
Eiglmeier, K.2
Marmiesse, M.3
Billault, A.4
Garnier, T.5
Niemann, S.6
Cole, S.T.7
Brosch, R.8
-
25
-
-
0017224835
-
Protective effects of M. microti vaccine against tuberculosis
-
L. Sula, and I. Radkovsky Protective effects of M. microti vaccine against tuberculosis J Hyg Epidemiol Microbiol Immunol 20 1976 1 6
-
(1976)
J Hyg Epidemiol Microbiol Immunol
, vol.20
, pp. 1-6
-
-
Sula, L.1
Radkovsky, I.2
-
26
-
-
0017386550
-
BCG and vole bacillus vaccines in the prevention of tuberculosis in adolescence and early adult life
-
P.D. Hart, and I. Sutherland BCG and vole bacillus vaccines in the prevention of tuberculosis in adolescence and early adult life Br Med J 2 1977 293 295
-
(1977)
Br Med J
, vol.2
, pp. 293-295
-
-
Hart, P.D.1
Sutherland, I.2
-
27
-
-
0036437048
-
Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti
-
A.S. Pym, P. Brodin, R. Brosch, M. Huerre, and S.T. Cole Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti Mol Microbiol 46 2002 709 717
-
(2002)
Mol Microbiol
, vol.46
, pp. 709-717
-
-
Pym, A.S.1
Brodin, P.2
Brosch, R.3
Huerre, M.4
Cole, S.T.5
-
28
-
-
0038751936
-
Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis
-
A.S. Pym, P. Brodin, L. Majlessi, R. Brosch, C. Demangel, A. Williams, K.E. Griffiths, G. Marchal, C. Leclerc, and S.T. Cole Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis Nat Med 9 2003 533 539
-
(2003)
Nat Med
, vol.9
, pp. 533-539
-
-
Pym, A.S.1
Brodin, P.2
Majlessi, L.3
Brosch, R.4
Demangel, C.5
Williams, A.6
Griffiths, K.E.7
Marchal, G.8
Leclerc, C.9
Cole, S.T.10
-
29
-
-
3042769443
-
Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens
-
P. Brodin, L. Majlessi, R. Brosch, D. Smith, G. Bancroft, S. Clark, A. Williams, C. Leclerc, and S.T. Cole Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens J Infect Dis 190 2004 115 122
-
(2004)
J Infect Dis
, vol.190
, pp. 115-122
-
-
Brodin, P.1
Majlessi, L.2
Brosch, R.3
Smith, D.4
Bancroft, G.5
Clark, S.6
Williams, A.7
Leclerc, C.8
Cole, S.T.9
-
30
-
-
29644438456
-
Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence
-
P. Brodin, L. Majlessi, L. Marsollier, M.I. de Jonge, D. Bottai, C. Demangel, J. Hinds, O. Neyrolles, P.D. Butcher, C. Leclerc, S.T. Cole, and R. Brosch Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence Infect Immun 74 2006 88 98
-
(2006)
Infect Immun
, vol.74
, pp. 88-98
-
-
Brodin, P.1
Majlessi, L.2
Marsollier, L.3
De Jonge, M.I.4
Bottai, D.5
Demangel, C.6
Hinds, J.7
Neyrolles, O.8
Butcher, P.D.9
Leclerc, C.10
Cole, S.T.11
Brosch, R.12
-
31
-
-
0142059794
-
The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue
-
T. Hsu, S.M. Hingley-Wilson, B. Chen, M. Chen, A.Z. Dai, P.M. Morin, C.B. Marks, J. Padiyar, C. Goulding, M. Gingery, D. Eisenberg, R.G. Russell, S.C. Derrick, F.M. Collins, S.L. Morris, C.H. King, and W.R. Jacobs Jr. The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue Proc Natl Acad Sci U S A 100 2003 12420 12425
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12420-12425
-
-
Hsu, T.1
Hingley-Wilson, S.M.2
Chen, B.3
Chen, M.4
Dai, A.Z.5
Morin, P.M.6
Marks, C.B.7
Padiyar, J.8
Goulding, C.9
Gingery, M.10
Eisenberg, D.11
Russell, R.G.12
Derrick, S.C.13
Collins, F.M.14
Morris, S.L.15
King, C.H.16
Jacobs, Jr.W.R.17
-
32
-
-
0037219942
-
Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guerin attenuation
-
K.N. Lewis, R. Liao, K.M. Guinn, M.J. Hickey, S. Smith, M.A. Behr, and D.R. Sherman Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guerin attenuation J Infect Dis 187 2003 117 123
-
(2003)
J Infect Dis
, vol.187
, pp. 117-123
-
-
Lewis, K.N.1
Liao, R.2
Guinn, K.M.3
Hickey, M.J.4
Smith, S.5
Behr, M.A.6
Sherman, D.R.7
-
33
-
-
0242268398
-
Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system
-
S.A. Stanley, S. Raghavan, W.W. Hwang, and J.S. Cox Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system Proc Natl Acad Sci U S A 100 2003 13001 13006
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 13001-13006
-
-
Stanley, S.A.1
Raghavan, S.2
Hwang, W.W.3
Cox, J.S.4
-
34
-
-
0032708648
-
Analysis of the proteome of Mycobacterium tuberculosis in silico
-
F. Tekaia, S.V. Gordon, T. Garnier, R. Brosch, B.G. Barrell, and S.T. Cole Analysis of the proteome of Mycobacterium tuberculosis in silico Tuber Lung Dis 79 1999 329 342
-
(1999)
Tuber Lung Dis
, vol.79
, pp. 329-342
-
-
Tekaia, F.1
Gordon, S.V.2
Garnier, T.3
Brosch, R.4
Barrell, B.G.5
Cole, S.T.6
-
35
-
-
0035231423
-
The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria
-
RESEARCH0044
-
N.C. Gey Van Pittius, J. Gamieldien, W. Hide, G.D. Brown, R.J. Siezen, and A.D. Beyers The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria Genome Biol 2 2001 RESEARCH0044
-
(2001)
Genome Biol
, vol.2
-
-
Gey Van Pittius, N.C.1
Gamieldien, J.2
Hide, W.3
Brown, G.D.4
Siezen, R.J.5
Beyers, A.D.6
-
36
-
-
84867442267
-
Composition of the type VII secretion system membrane complex
-
E.N. Houben, J. Bestebroer, R. Ummels, L. Wilson, S.R. Piersma, C.R. Jimenez, T.H. Ottenhoff, J. Luirink, and W. Bitter Composition of the type VII secretion system membrane complex Mol Microbiol 86 2012 472 484
-
(2012)
Mol Microbiol
, vol.86
, pp. 472-484
-
-
Houben, E.N.1
Bestebroer, J.2
Ummels, R.3
Wilson, L.4
Piersma, S.R.5
Jimenez, C.R.6
Ottenhoff, T.H.7
Luirink, J.8
Bitter, W.9
-
37
-
-
84858276262
-
Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation
-
D. Bottai, M. Di Luca, L. Majlessi, W. Frigui, R. Simeone, F. Sayes, W. Bitter, M.J. Brennan, C. Leclerc, G. Batoni, M. Campa, R. Brosch, and S. Esin Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation Mol Microbiol 83 2012 1195 1209
-
(2012)
Mol Microbiol
, vol.83
, pp. 1195-1209
-
-
Bottai, D.1
Di Luca, M.2
Majlessi, L.3
Frigui, W.4
Simeone, R.5
Sayes, F.6
Bitter, W.7
Brennan, M.J.8
Leclerc, C.9
Batoni, G.10
Campa, M.11
Brosch, R.12
Esin, S.13
-
38
-
-
70350445687
-
Characterization of a Mycobacterium tuberculosis ESX-3 conditional mutant: Essentiality and rescue by iron and zinc
-
A. Serafini, F. Boldrin, G. Palu, and R. Manganelli Characterization of a Mycobacterium tuberculosis ESX-3 conditional mutant: essentiality and rescue by iron and zinc J Bacteriol 191 2009 6340 6344
-
(2009)
J Bacteriol
, vol.191
, pp. 6340-6344
-
-
Serafini, A.1
Boldrin, F.2
Palu, G.3
Manganelli, R.4
-
39
-
-
73649100289
-
Systematic genetic nomenclature for type VII secretion systems
-
W. Bitter, E.N. Houben, D. Bottai, P. Brodin, E.J. Brown, J.S. Cox, K. Derbyshire, S.M. Fortune, L.Y. Gao, J. Liu, N.C. Gey van Pittius, A.S. Pym, E.J. Rubin, D.R. Sherman, S.T. Cole, and R. Brosch Systematic genetic nomenclature for type VII secretion systems PLoS Pathog 5 2009 e1000507
-
(2009)
PLoS Pathog
, vol.5
, pp. e1000507
-
-
Bitter, W.1
Houben, E.N.2
Bottai, D.3
Brodin, P.4
Brown, E.J.5
Cox, J.S.6
Derbyshire, K.7
Fortune, S.M.8
Gao, L.Y.9
Liu, J.10
Gey Van Pittius, N.C.11
Pym, A.S.12
Rubin, E.J.13
Sherman, D.R.14
Cole, S.T.15
Brosch, R.16
-
40
-
-
0034702898
-
The mycosins of Mycobacterium tuberculosis H37Rv: A family of subtilisin-like serine proteases
-
G.D. Brown, J.A. Dave, N.C. Gey van Pittius, L. Stevens, M.R. Ehlers, and A.D. Beyers The mycosins of Mycobacterium tuberculosis H37Rv: a family of subtilisin-like serine proteases Gene 254 2000 147 155
-
(2000)
Gene
, vol.254
, pp. 147-155
-
-
Brown, G.D.1
Dave, J.A.2
Gey Van Pittius, N.C.3
Stevens, L.4
Ehlers, M.R.5
Beyers, A.D.6
-
41
-
-
34248374200
-
Mycosin-1, a subtilisin-like serine protease of Mycobacterium tuberculosis, is cell wall-associated and expressed during infection of macrophages
-
J.A. Dave, N.C. Gey van Pittius, A.D. Beyers, M.R. Ehlers, and G.D. Brown Mycosin-1, a subtilisin-like serine protease of Mycobacterium tuberculosis, is cell wall-associated and expressed during infection of macrophages BMC Microbiol 2 2002 30
-
(2002)
BMC Microbiol
, vol.2
, pp. 30
-
-
Dave, J.A.1
Gey Van Pittius, N.C.2
Beyers, A.D.3
Ehlers, M.R.4
Brown, G.D.5
-
42
-
-
77749336398
-
Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence
-
Y.M. Ohol, D.H. Goetz, K. Chan, M.U. Shiloh, C.S. Craik, and J.S. Cox Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence Cell Host Microbe 7 2010 210 220
-
(2010)
Cell Host Microbe
, vol.7
, pp. 210-220
-
-
Ohol, Y.M.1
Goetz, D.H.2
Chan, K.3
Shiloh, M.U.4
Craik, C.S.5
Cox, J.S.6
-
43
-
-
33751323180
-
Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions
-
N.C. Gey van Pittius, S.L. Sampson, H. Lee, Y. Kim, P.D. van Helden, and R.M. Warren Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions BMC Evol Biol 6 2006 95
-
(2006)
BMC Evol Biol
, vol.6
, pp. 95
-
-
Gey Van Pittius, N.C.1
Sampson, S.L.2
Lee, H.3
Kim, Y.4
Van Helden, P.D.5
Warren, R.M.6
-
44
-
-
1842588596
-
Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6
-
C. Demangel, P. Brodin, P.J. Cockle, R. Brosch, L. Majlessi, C. Leclerc, and S.T. Cole Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6 Infect Immun 72 2004 2170 2176
-
(2004)
Infect Immun
, vol.72
, pp. 2170-2176
-
-
Demangel, C.1
Brodin, P.2
Cockle, P.J.3
Brosch, R.4
Majlessi, L.5
Leclerc, C.6
Cole, S.T.7
-
45
-
-
84859965450
-
Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 Type VII secretion -encoded PE-PPE proteins predicts vaccine potential
-
F. Sayes, L. Sun, M. Di Luca, R. Simeone, N. Degaiffier, L. Fiette, S. Esin, R. Brosch, D. Bottai, C. Leclerc, and L. Majlessi Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 Type VII secretion -encoded PE-PPE proteins predicts vaccine potential Cell Host Microbe 11 2012 352 363
-
(2012)
Cell Host Microbe
, vol.11
, pp. 352-363
-
-
Sayes, F.1
Sun, L.2
Di Luca, M.3
Simeone, R.4
Degaiffier, N.5
Fiette, L.6
Esin, S.7
Brosch, R.8
Bottai, D.9
Leclerc, C.10
Majlessi, L.11
-
46
-
-
84873095223
-
Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis
-
P. Supply, M. Marceau, S. Mangenot, D. Roche, C. Rouanet, V. Khanna, L. Majlessi, A. Criscuolo, J. Tap, A. Pawlik, L. Fiette, M. Orgeur, M. Fabre, C. Parmentier, W. Frigui, R. Simeone, E.C. Boritsch, A.S. Debrie, E. Willery, D. Walker, M.A. Quail, L. Ma, C. Bouchier, G. Salvignol, F. S, A. Cascioferro, T. Seemann, V. Barbe, C. Locht, M.C. Gutierrez, C. Leclerc, S.D. Bentley, T.P. Stinear, S. Brisse, C. Médigue, J. Parkhill, S. Cruveiller, and R. Brosch Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis Nat Genet 45 2013 172 179
-
(2013)
Nat Genet
, vol.45
, pp. 172-179
-
-
Supply, P.1
Marceau, M.2
Mangenot, S.3
Roche, D.4
Rouanet, C.5
Khanna, V.6
Majlessi, L.7
Criscuolo, A.8
Tap, J.9
Pawlik, A.10
Fiette, L.11
Orgeur, M.12
Fabre, M.13
Parmentier, C.14
Frigui, W.15
Simeone, R.16
Boritsch, E.C.17
Debrie, A.S.18
Willery, E.19
Walker, D.20
Quail, M.A.21
Ma, L.22
Bouchier, C.23
Salvignol, G.24
Cascioferro, A.25
Seemann, T.26
Barbe, V.27
Locht, C.28
Gutierrez, M.C.29
Leclerc, C.30
Bentley, S.D.31
Stinear, T.P.32
Brisse, S.33
Médigue, C.34
Parkhill, J.35
Cruveiller, S.36
Brosch, R.37
more..
-
47
-
-
25144441735
-
A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis
-
J.A. MacGurn, S. Raghavan, S.A. Stanley, and J.S. Cox A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis Mol Microbiol 57 2005 1653 1663
-
(2005)
Mol Microbiol
, vol.57
, pp. 1653-1663
-
-
MacGurn, J.A.1
Raghavan, S.2
Stanley, S.A.3
Cox, J.S.4
-
48
-
-
23044481526
-
Mutually dependent secretion of proteins required for mycobacterial virulence
-
S.M. Fortune, A. Jaeger, D.A. Sarracino, M.R. Chase, C.M. Sassetti, D.R. Sherman, B.R. Bloom, and E.J. Rubin Mutually dependent secretion of proteins required for mycobacterial virulence Proc Natl Acad Sci U S A 102 2005 10676 10681
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 10676-10681
-
-
Fortune, S.M.1
Jaeger, A.2
Sarracino, D.A.3
Chase, M.R.4
Sassetti, C.M.5
Sherman, D.R.6
Bloom, B.R.7
Rubin, E.J.8
-
49
-
-
84884285987
-
Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA-independent virulence
-
J.M. Chen, M. Zhang, J. Rybniker, S. Boy-Rottger, N. Dhar, F. Pojer, and S.T. Cole Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA-independent virulence Mol Microbiol 89 2013 1154 1166
-
(2013)
Mol Microbiol
, vol.89
, pp. 1154-1166
-
-
Chen, J.M.1
Zhang, M.2
Rybniker, J.3
Boy-Rottger, S.4
Dhar, N.5
Pojer, F.6
Cole, S.T.7
-
50
-
-
79953310102
-
ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis
-
D. Bottai, L. Majlessi, R. Simeone, W. Frigui, C. Laurent, P. Lenormand, J. Chen, I. Rosenkrands, M. Huerre, C. Leclerc, S.T. Cole, and R. Brosch ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis J Infect Dis 203 2011 1155 1164
-
(2011)
J Infect Dis
, vol.203
, pp. 1155-1164
-
-
Bottai, D.1
Majlessi, L.2
Simeone, R.3
Frigui, W.4
Laurent, C.5
Lenormand, P.6
Chen, J.7
Rosenkrands, I.8
Huerre, M.9
Leclerc, C.10
Cole, S.T.11
Brosch, R.12
-
51
-
-
40349106159
-
Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP
-
W. Frigui, D. Bottai, L. Majlessi, M. Monot, E. Josselin, P. Brodin, T. Garnier, B. Gicquel, C. Martin, C. Leclerc, S. Cole, and R. Brosch Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP PLoS Pathog 4 2008 e33
-
(2008)
PLoS Pathog
, vol.4
, pp. e33
-
-
Frigui, W.1
Bottai, D.2
Majlessi, L.3
Monot, M.4
Josselin, E.5
Brodin, P.6
Garnier, T.7
Gicquel, B.8
Martin, C.9
Leclerc, C.10
Cole, S.11
Brosch, R.12
-
52
-
-
84861210509
-
Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein
-
B. Blasco, J.M. Chen, R. Hartkoorn, C. Sala, S. Uplekar, J. Rougemont, F. Pojer, and S.T. Cole Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein PLoS Pathog 8 2012 e1002621
-
(2012)
PLoS Pathog
, vol.8
, pp. e1002621
-
-
Blasco, B.1
Chen, J.M.2
Hartkoorn, R.3
Sala, C.4
Uplekar, S.5
Rougemont, J.6
Pojer, F.7
Cole, S.T.8
-
53
-
-
84872026611
-
MprAB regulates the espA operon in Mycobacterium tuberculosis and modulates ESX-1 function and host cytokine response
-
X. Pang, B. Samten, G. Cao, X. Wang, A.R. Tvinnereim, X.L. Chen, and S.T. Howard MprAB regulates the espA operon in Mycobacterium tuberculosis and modulates ESX-1 function and host cytokine response J Bacteriol 195 2013 66 75
-
(2013)
J Bacteriol
, vol.195
, pp. 66-75
-
-
Pang, X.1
Samten, B.2
Cao, G.3
Wang, X.4
Tvinnereim, A.R.5
Chen, X.L.6
Howard, S.T.7
-
54
-
-
84859972311
-
Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death
-
R. Simeone, A. Bobard, J. Lippmann, W. Bitter, L. Majlessi, R. Brosch, and J. Enninga Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death PLoS Pathog 8 2012 e1002507
-
(2012)
PLoS Pathog
, vol.8
, pp. e1002507
-
-
Simeone, R.1
Bobard, A.2
Lippmann, J.3
Bitter, W.4
Majlessi, L.5
Brosch, R.6
Enninga, J.7
-
55
-
-
47749109112
-
The specialized secretory apparatus ESX-1 is essential for DNA transfer in Mycobacterium smegmatis
-
A. Coros, B. Callahan, E. Battaglioli, and K.M. Derbyshire The specialized secretory apparatus ESX-1 is essential for DNA transfer in Mycobacterium smegmatis Mol Microbiol 69 2008 794 808
-
(2008)
Mol Microbiol
, vol.69
, pp. 794-808
-
-
Coros, A.1
Callahan, B.2
Battaglioli, E.3
Derbyshire, K.M.4
-
56
-
-
84880938874
-
Distributive conjugal transfer in mycobacteria generates progeny with meiotic-like genome-wide mosaicism, allowing mapping of a mating identity locus
-
T. Gray, J. Krywy, J. Harold, M. Palumbo, and K. Derbyshire Distributive conjugal transfer in mycobacteria generates progeny with meiotic-like genome-wide mosaicism, allowing mapping of a mating identity locus PLoS Biol 11 2013 e1001602
-
(2013)
PLoS Biol
, vol.11
, pp. e1001602
-
-
Gray, T.1
Krywy, J.2
Harold, J.3
Palumbo, M.4
Derbyshire, K.5
-
57
-
-
60049091769
-
ESX/type VII secretion systems and their role in host-pathogen interaction
-
R. Simeone, D. Bottai, and R. Brosch ESX/type VII secretion systems and their role in host-pathogen interaction Curr Opin Microbiol 12 2009 4 10
-
(2009)
Curr Opin Microbiol
, vol.12
, pp. 4-10
-
-
Simeone, R.1
Bottai, D.2
Brosch, R.3
-
58
-
-
34250716965
-
J. PP. M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells
-
N. van der Wel, D. Hava, D. Houben, D. Fluitsma, M. van Zon, J. Pierson, and M. Brenner J. PP. M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells Cell 129 2007 1287 1298
-
(2007)
Cell
, vol.129
, pp. 1287-1298
-
-
Van Der Wel, N.1
Hava, D.2
Houben, D.3
Fluitsma, D.4
Van Zon, M.5
Pierson, J.6
Brenner, M.7
-
59
-
-
84863993689
-
ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria
-
D. Houben, C. Demangel, J. van Ingen, J. Perez, L. Baldeon, A.M. Abdallah, L. Caleechurn, D. Bottai, M. van Zon, K. de Punder, T. van der Laan, A. Kant, R. Bossers-de Vries, P. Willemsen, W. Bitter, D. van Soolingen, R. Brosch, N. van der Wel, and P.J. Peters ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria Cell Microbiol 14 2012 1287 1298
-
(2012)
Cell Microbiol
, vol.14
, pp. 1287-1298
-
-
Houben, D.1
Demangel, C.2
Van Ingen, J.3
Perez, J.4
Baldeon, L.5
Abdallah, A.M.6
Caleechurn, L.7
Bottai, D.8
Van Zon, M.9
De Punder, K.10
Van Der Laan, T.11
Kant, A.12
Bossers-De Vries, R.13
Willemsen, P.14
Bitter, W.15
Van Soolingen, D.16
Brosch, R.17
Van Der Wel, N.18
Peters, P.J.19
-
60
-
-
34547766513
-
ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity
-
M.I. de Jonge, G. Pehau-Arnaudet, M.M. Fretz, F. Romain, D. Bottai, P. Brodin, N. Honore, G. Marchal, W. Jiskoot, P. England, S.T. Cole, and R. Brosch ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity J Bacteriol 189 2007 6028 6034
-
(2007)
J Bacteriol
, vol.189
, pp. 6028-6034
-
-
De Jonge, M.I.1
Pehau-Arnaudet, G.2
Fretz, M.M.3
Romain, F.4
Bottai, D.5
Brodin, P.6
Honore, N.7
Marchal, G.8
Jiskoot, W.9
England, P.10
Cole, S.T.11
Brosch, R.12
-
61
-
-
84871752747
-
Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis
-
J. De Leon, G. Jiang, Y. Ma, E. Rubin, S. Fortune, and J. Sun Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis J Biol Chem 287 2012 44184 44191
-
(2012)
J Biol Chem
, vol.287
, pp. 44184-44191
-
-
De Leon, J.1
Jiang, G.2
Ma, Y.3
Rubin, E.4
Fortune, S.5
Sun, J.6
-
62
-
-
34248402030
-
Genome plasticity of BCG and impact on vaccine efficacy
-
R. Brosch, S.V. Gordon, T. Garnier, K. Eiglmeier, W. Frigui, P. Valenti, S. Dos Santos, S. Duthoy, C. Lacroix, C. Garcia-Pelayo, J.K. Inwald, P. Golby, J.N. Garcia, G.R. Hewinson, M.A. Behr, M.A. Quail, C. Churcher, B.G. Barrell, J. Parhill, and S.T. Cole Genome plasticity of BCG and impact on vaccine efficacy Proc Natl Acad Sci U S A 104 2007 5596 5601
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 5596-5601
-
-
Brosch, R.1
Gordon, S.V.2
Garnier, T.3
Eiglmeier, K.4
Frigui, W.5
Valenti, P.6
Dos Santos, S.7
Duthoy, S.8
Lacroix, C.9
Garcia-Pelayo, C.10
Inwald, J.K.11
Golby, P.12
Garcia, J.N.13
Hewinson, G.R.14
Behr, M.A.15
Quail, M.A.16
Churcher, C.17
Barrell, B.G.18
Parhill, J.19
Cole, S.T.20
more..
-
63
-
-
0942290453
-
Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis
-
K.I. Guinn, M.J. Hickey, S.K. Mathur, K.L. Zakel, J.E. Grotzke, D.M. Lewinsohn, S. Smith, and D.R. Sherman Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis Mol Microbiol 51 2004 359 370
-
(2004)
Mol Microbiol
, vol.51
, pp. 359-370
-
-
Guinn, K.I.1
Hickey, M.J.2
Mathur, S.K.3
Zakel, K.L.4
Grotzke, J.E.5
Lewinsohn, D.M.6
Smith, S.7
Sherman, D.R.8
-
64
-
-
84887611505
-
ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis
-
J. Aguilo, H. Alonso, S. Uranga, D. Marinova, A. Arbues, A. de Martino, A. Anel, M. Monzon, J. Badiola, J. Pardo, R. Brosch, and C. Martin ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis Cell Microbiol 15 2013 1994 2005
-
(2013)
Cell Microbiol
, vol.15
, pp. 1994-2005
-
-
Aguilo, J.1
Alonso, H.2
Uranga, S.3
Marinova, D.4
Arbues, A.5
De Martino, A.6
Anel, A.7
Monzon, M.8
Badiola, J.9
Pardo, J.10
Brosch, R.11
Martin, C.12
-
65
-
-
84865220380
-
Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway
-
R.O. Watson, P.S. Manzanillo, and J.S. Cox Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway Cell 150 2012 803 815
-
(2012)
Cell
, vol.150
, pp. 803-815
-
-
Watson, R.O.1
Manzanillo, P.S.2
Cox, J.S.3
-
66
-
-
84866554596
-
ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells
-
A. Romagnoli, M.P. Etna, E. Giacomini, M. Pardini, M.E. Remoli, M. Corazzari, L. Falasca, D. Goletti, V. Gafa, R. Simeone, G. Delogu, M. Piacentini, R. Brosch, G.M. Fimia, and E.M. Coccia ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells Autophagy 8 2012 1357 1370
-
(2012)
Autophagy
, vol.8
, pp. 1357-1370
-
-
Romagnoli, A.1
Etna, M.P.2
Giacomini, E.3
Pardini, M.4
Remoli, M.E.5
Corazzari, M.6
Falasca, L.7
Goletti, D.8
Gafa, V.9
Simeone, R.10
Delogu, G.11
Piacentini, M.12
Brosch, R.13
Fimia, G.M.14
Coccia, E.M.15
-
67
-
-
77957133396
-
Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome
-
B.B. Mishra, P. Moura-Alves, A. Sonawane, N. Hacohen, G. Griffiths, L.F. Moita, and E. Anes Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome Cell Microbiol 12 2010 1046 1063
-
(2010)
Cell Microbiol
, vol.12
, pp. 1046-1063
-
-
Mishra, B.B.1
Moura-Alves, P.2
Sonawane, A.3
Hacohen, N.4
Griffiths, G.5
Moita, L.F.6
Anes, E.7
-
68
-
-
80051810145
-
Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis
-
K.W. Wong, and W.R. Jacobs Jr. Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis Cell Microbiol 13 2011 1371 1384
-
(2011)
Cell Microbiol
, vol.13
, pp. 1371-1384
-
-
Wong, K.W.1
Jacobs, Jr.W.R.2
-
69
-
-
84856033488
-
Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis
-
A. Dorhoi, G. Nouailles, S. Jorg, K. Hagens, E. Heinemann, L. Pradl, D. Oberbeck-Muller, M.A. Duque-Correa, S.T. Reece, J. Ruland, R. Brosch, J. Tschopp, O. Gross, and S.H.E. Kaufmann Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis Eur J Immunol 42 2012 374 384
-
(2012)
Eur J Immunol
, vol.42
, pp. 374-384
-
-
Dorhoi, A.1
Nouailles, G.2
Jorg, S.3
Hagens, K.4
Heinemann, E.5
Pradl, L.6
Oberbeck-Muller, D.7
Duque-Correa, M.A.8
Reece, S.T.9
Ruland, J.10
Brosch, R.11
Tschopp, J.12
Gross, O.13
Kaufmann, S.H.E.14
-
70
-
-
33847359299
-
The type i IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis
-
S.A. Stanley, J.E. Johndrow, P. Manzanillo, and J.S. Cox The type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis J Immunol 178 2007 3143 3152
-
(2007)
J Immunol
, vol.178
, pp. 3143-3152
-
-
Stanley, S.A.1
Johndrow, J.E.2
Manzanillo, P.3
Cox, J.S.4
-
71
-
-
67449113507
-
Antigen load governs the differential priming of CD8 T cells in response to the bacille Calmette Guerin vaccine or Mycobacterium tuberculosis infection
-
A.A. Ryan, J.K. Nambiar, T.M. Wozniak, B. Roediger, E. Shklovskaya, W.J. Britton, B. Fazekas de St Groth, and J.A. Triccas Antigen load governs the differential priming of CD8 T cells in response to the bacille Calmette Guerin vaccine or Mycobacterium tuberculosis infection J Immunol 182 2009 7172 7177
-
(2009)
J Immunol
, vol.182
, pp. 7172-7177
-
-
Ryan, A.A.1
Nambiar, J.K.2
Wozniak, T.M.3
Roediger, B.4
Shklovskaya, E.5
Britton, W.J.6
Fazekas De St Groth, B.7
Triccas, J.A.8
-
72
-
-
67651233950
-
PPE and PE-PGRS proteins of Mycobacterium marinum are transported via the type VII secretion system ESX-5
-
A.M. Abdallah, T. Verboom, E.M. Weerdenburg, N.C. Gey van Pittius, P.W. Mahasha, C. Jimenez, M. Parra, N. Cadieux, M.J. Brennan, B.J. Appelmelk, and W. Bitter PPE and PE-PGRS proteins of Mycobacterium marinum are transported via the type VII secretion system ESX-5 Mol Microbiol 73 2009 329 340
-
(2009)
Mol Microbiol
, vol.73
, pp. 329-340
-
-
Abdallah, A.M.1
Verboom, T.2
Weerdenburg, E.M.3
Gey Van Pittius, N.C.4
Mahasha, P.W.5
Jimenez, C.6
Parra, M.7
Cadieux, N.8
Brennan, M.J.9
Appelmelk, B.J.10
Bitter, W.11
-
73
-
-
84871289607
-
The ESX-5 associated eccB-eccC Locus is essential for Mycobacterium tuberculosis viability
-
M. Di Luca, D. Bottai, G. Batoni, M. Orgeur, A. Aulicino, C. Counoupas, M. Campa, R. Brosch, and S. Esin The ESX-5 associated eccB-eccC Locus is essential for Mycobacterium tuberculosis viability PLoS One 7 2012 e52059
-
(2012)
PLoS One
, vol.7
, pp. e52059
-
-
Di Luca, M.1
Bottai, D.2
Batoni, G.3
Orgeur, M.4
Aulicino, A.5
Counoupas, C.6
Campa, M.7
Brosch, R.8
Esin, S.9
-
74
-
-
33749997722
-
A specific secretion system mediates PPE41 transport in pathogenic mycobacteria
-
A.M. Abdallah, T. Verboom, F. Hannes, M. Safi, M. Strong, D. Eisenberg, R.J. Musters, C.M. Vandenbroucke-Grauls, B.J. Appelmelk, J. Luirink, and W. Bitter A specific secretion system mediates PPE41 transport in pathogenic mycobacteria Mol Microbiol 62 2006 667 679
-
(2006)
Mol Microbiol
, vol.62
, pp. 667-679
-
-
Abdallah, A.M.1
Verboom, T.2
Hannes, F.3
Safi, M.4
Strong, M.5
Eisenberg, D.6
Musters, R.J.7
Vandenbroucke-Grauls, C.M.8
Appelmelk, B.J.9
Luirink, J.10
Bitter, W.11
-
75
-
-
84863928050
-
General secretion signal for the mycobacterial type VII secretion pathway
-
M.H. Daleke, R. Ummels, P. Bawono, J. Heringa, C.M. Vandenbroucke-Grauls, J. Luirink, and W. Bitter General secretion signal for the mycobacterial type VII secretion pathway Proc Natl Acad Sci U S A 109 2012 11342 11347
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 11342-11347
-
-
Daleke, M.H.1
Ummels, R.2
Bawono, P.3
Heringa, J.4
Vandenbroucke-Grauls, C.M.5
Luirink, J.6
Bitter, W.7
-
76
-
-
67651207964
-
PPE and ESX clusters: Novel insights into the secretion of these most unusual protein families
-
D. Bottai, R. Brosch, and P.E. Mycobacterial PPE and ESX clusters: novel insights into the secretion of these most unusual protein families Mol Microbiol 73 2009 325 328
-
(2009)
Mol Microbiol
, vol.73
, pp. 325-328
-
-
Bottai, D.1
Brosch, R.2
Mycobacterial, P.E.3
-
77
-
-
36549015553
-
PE is a functional domain responsible for protein translocation and localization on mycobacterial cell wall
-
A. Cascioferro, G. Delogu, M. Colone, M. Sali, A. Stringaro, G. Arancia, G. Fadda, G. Palu, and R. Manganelli PE is a functional domain responsible for protein translocation and localization on mycobacterial cell wall Mol Microbiol 66 2007 1536 1547
-
(2007)
Mol Microbiol
, vol.66
, pp. 1536-1547
-
-
Cascioferro, A.1
Delogu, G.2
Colone, M.3
Sali, M.4
Stringaro, A.5
Arancia, G.6
Fadda, G.7
Palu, G.8
Manganelli, R.9
-
78
-
-
73249128210
-
Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition
-
M.S. Siegrist, M. Unnikrishnan, M.J. McConnell, M. Borowsky, T.Y. Cheng, N. Siddiqi, S.M. Fortune, D.B. Moody, and E.J. Rubin Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition Proc Natl Acad Sci U S A 106 2009 18792 18797
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 18792-18797
-
-
Siegrist, M.S.1
Unnikrishnan, M.2
McConnell, M.J.3
Borowsky, M.4
Cheng, T.Y.5
Siddiqi, N.6
Fortune, S.M.7
Moody, D.B.8
Rubin, E.J.9
-
79
-
-
78049264734
-
Towards anti-virulence drugs targeting ESX-1 mediated pathogenesis of Mycobacterium tuberculosis
-
J.M. Chen, F. Pojer, B. Blasco, and S.T. Cole Towards anti-virulence drugs targeting ESX-1 mediated pathogenesis of Mycobacterium tuberculosis Drug Discov Today Dis Mech 7 2010 e25 e31
-
(2010)
Drug Discov Today Dis Mech
, vol.7
, pp. e25-e31
-
-
Chen, J.M.1
Pojer, F.2
Blasco, B.3
Cole, S.T.4
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