The new latex allergen Hev b 15: IgE-binding properties of a recombinant serine protease inhibitor

Journal of Investigational Allergology and Clinical Immunology

Volumn 25, Issue 2, 2015, Pages 160-162

  Rihs, Hans Peter ^a   Sander, I ^a   Heimann, H ^a   Meurer, U ^a   Bruning T ^a   Raulf, M ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Hev b 15. IgE binding; Hevea brasiliensis; Recombinant allergen; Serine protease inhibitor

Indexed keywords

ALLERGEN; IMMUNOGLOBULIN E; LATEX; MALTOSE BINDING PROTEIN; RECOMBINANT SERINE PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; HEV B 10, LATEX; PLANT ANTIGEN; PROTEIN BINDING; RECOMBINANT PROTEIN; VEGETABLE PROTEIN;

ADULT; ALLERGY; ARTICLE; CLINICAL ARTICLE; ESCHERICHIA COLI; FEMALE; HEVEA BRASILIENSIS; HUMAN; OCCUPATIONAL ALLERGY; PLANT LEAF; PRICK TEST; PROTEIN BINDING; BLOOD; CHEMICALLY INDUCED; IMMUNOLOGY; LATEX HYPERSENSITIVITY; PREDICTIVE VALUE;

ANTIGENS, PLANT; HUMANS; IMMUNOGLOBULIN E; LATEX; LATEX HYPERSENSITIVITY; PLANT LEAVES; PLANT PROTEINS; PREDICTIVE VALUE OF TESTS; PROTEIN BINDING; RECOMBINANT PROTEINS; SERINE PROTEINASE INHIBITORS;

EID: 84931463155     PISSN: 10189068     EISSN: 16980808     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Constantin C, Quirce S, Grote M, Touraev A, Swoboda I, Stoecklinger A, Mari A, Thalhamer J, Heberle-Bors E, Valenta R. Molecular and immunological characterization of a wheat serine proteinase inhibitor as a novel allergen in baker's asthma. J Immunol. 2008;180:7451-60.
2. Rihs HP, Chen Z, Schumacher S, Rozynek P, Cremer R, Lundberg M, Raulf-Heimsoth M, Petersen A, Baur X. Recombinant Hev b 1: large-scale production and immunological characterization. Clin Exp Allergy. 2000;30:1285-92.
3. Sander I, Kespohl S, Merget R, Goldscheid N, Degens PO, Brüning T, Raulf-Heimsoth M. A new method to bind allergens for the measurement of specific IgE antibodies. Int Arch Allergy Immunol. 2005;136:39-44.
4. Bradford M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-54.
5. Raulf-Heimsoth M, Rihs HP, Rozynek P, Cremer R, Gaspar A, Pires G, Yeang HY, Arif SA, Hamilton RG, Sander I, Lundberg M, Brüning T. Quantitative analysis of IgE reactivity profiles in patients allergic or sensitized to natural rubber latex. Clin Exp Allergy. 2007;37:1657-67.