Frailty before critical illness and mortality for elderly medicare beneficiaries

Journal of the American Geriatrics Society

Volumn 63, Issue 6, 2015, Pages 1121-1128

  Hope, Aluko A ^a   Gong, Michelle N ^a   Guerra, Carmen ^b   Wunsch, Hannah ^a,c  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^c Mailman School of Public Health   (United States)

Author keywords

aged; critical illness; frailty; Medicare; prognosis

Indexed keywords

AGED; ARTICLE; CANCER PROGNOSIS; COHORT ANALYSIS; CONFIDENCE INTERVAL; CRITICAL ILLNESS; CRITICALLY ILL PATIENT; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; FRAIL ELDERLY; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MEDICARE; MORTALITY; MULTIPLE ORGAN FAILURE; NEOPLASM; ORGAN; PROPORTIONAL HAZARDS MODEL; RISK ASSESSMENT; SURVIVOR; EPIDEMIOLOGY; GERIATRIC ASSESSMENT; HOSPITALIZATION; RISK FACTOR; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; TRENDS; UNITED STATES; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CRITICAL ILLNESS; FEMALE; FRAIL ELDERLY; GERIATRIC ASSESSMENT; HOSPITAL MORTALITY; HOSPITALIZATION; HUMANS; INTENSIVE CARE UNITS; LOGISTIC MODELS; MALE; MEDICARE; RISK FACTORS; SURVIVORS; UNITED STATES;

EID: 84931441185     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/jgs.13436     Document Type: Article

References (31)

1. Carson SS,. The epidemiology of critical illness in the elderly. Crit Care Clin 2003; 19: 605-617.
2. Orwelius L, Nordlund A, Nordlund P, et al., Pre-existing disease: The most important factor for health related quality of life long-term after critical illness: A prospective, longitudinal, multicentre trial. Crit Care 2010; 14: R67.
3. Sligl WI, Eurich DT, Marrie TJ, et al., Only severely limited, premorbid functional status is associated with short- and long-term mortality in patients with pneumonia who are critically ill: A prospective observational study. Chest 2011; 139: 88-94.
4. Roch A, Wiramus S, Pauly V, et al., Long-term outcome in medical patients aged 80 or over following admission to an intensive care unit. Crit Care 2011; 15: R36.
5. Lunney JR, Lynn J, Hogan C,. Profiles of older Medicare decedents. J Am Geriatr Soc 2002; 50: 1108-1112.
6. Lunney JR, Lynn J, Foley DJ, et al., Patterns of functional decline at the end of life. JAMA 2003; 289: 2387-2392.
7. Woods NF, LaCroix AZ, Gray SL, et al., Frailty: Emergence and consequences in women aged 65 and older in the Women's Health Initiative Observational Study. J Am Geriatr Soc 2005; 53: 1321-1330.
8. Fried LP, Tangen CM, Walston J, et al., Frailty in older adults: Evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001; 56A: M146-M156.
9. Robinson TN, Wallace JI, Wu DS, et al., Accumulated frailty characteristics predict postoperative discharge institutionalization in the geriatric patient. J Am Coll Surg 2011; 213: 37-42.
10. Robinson TN, Wu DS, Stiegmann GV, et al., Frailty predicts increased hospital and six-month healthcare cost following colorectal surgery in older adults. Am J Surg 2011; 202: 511-514.
11. Aaldriks AA, van der Geest LG, Giltay EJ, et al., Frailty and malnutrition predictive of mortality risk in older patients with advanced colorectal cancer receiving chemotherapy. J Geriatr Oncol 2013; 4: 218-226.
12. Iwashyna TJ, Prescott HC,. When is critical illness not like an asteroid strike? Am J Respir Crit Care Med 2013; 188: 525-527.
13. Iwashyna TJ, Netzer G, Langa KM, et al., Spurious inferences about long-term outcomes: The case of severe sepsis and geriatric conditions. Am J Respir Crit Care Med 2012; 185: 835-841.
14. Barnato AE, Labor RE, Freeborne NE, et al., Qualitative analysis of Medicare claims in the last 3 years of life: A pilot study. J Am Geriatr Soc 2005; 53: 66-73.
15. Sternberg SA, Wershof Schwartz A, Karunananthan S, et al., The identification of frailty: A systematic literature review. J Am Geriatr Soc 2011; 59: 2129-2138.
16. de Vries NM, Staal JB, van Ravensberg CD, et al., Outcome instruments to measure frailty: A systematic review. Ageing Res Rev 2011; 10: 104-114.
17. Kahn JM, Carson SS, Angus DC, et al., Development and validation of an algorithm for identifying prolonged mechanical ventilation in administrative data. Health Serv Outcomes Res Method 2009; 9: 117-132.
18. Kaplan V, Angus DC, Griffin MF, et al., Hospitalized community-acquired pneumonia in the elderly: Age- and sex-related patterns of care and outcome in the United States. Am J Respir Crit Care Med 2002; 165: 766-772.
19. Angus DC, Linde-Zwirble WT, Lidicker J, et al., Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001; 29: 1303-1310.
20. Wunsch H, Linde-Zwirble WT, Angus DC, et al., The epidemiology of mechanical ventilation use in the United States. Crit Care Med 2010; 38: 1947-1953.
21. Cigolle CT, Ofstedal MB, Tian Z, et al., Comparing models of frailty: The Health and Retirement Study. J Am Geriatr Soc 2009; 57: 830-839.
22. Inouye SK, Studenski S, Tinetti ME, et al., Geriatric syndromes: Clinical, research, and policy implications of a core geriatric concept. J Am Geriatr Soc 2007; 55: 780-791.
23. Bagshaw SM, Stelfox T, McDermid RC, et al., Association between frailty and short- and long-term outcomes among critically ill patients: A multicentre prospective cohort study. Can Med Assoc J 2013; 10: 1503.
24. McDermid RC, Stelfox HT, Bagshaw SM,. Frailty in the critically ill: A novel concept. Crit Care 2011; 15: 301.
25. Hilmer SN, Perera V, Mitchell S, et al., The assessment of frailty in older people in acute care. Australas J Ageing 2009; 28: 182-188.
26. Herridge MS, Cheung AM, Tansey CM, et al., One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med 2003; 348: 683-693.
27. Herridge MS, Tansey CM, Matte A, et al., Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med 2011; 364: 1293-1304.
28. de Jonghe B, Lacherade JC, Sharshar T, et al., Intensive care unit-acquired weakness: Risk factors and prevention. Crit Care Med 2009; 37: S309-S315.
29. van der Schaaf M, Beelen A, Dongelmans DA, et al., Poor functional recovery after a critical illness: A longitudinal study. J Rehabil Med 1041; 41: 1041-1048.
30. Ehlenbach WJ, Hough CL, Crane PK, et al., Association between acute care and critical illness hospitalization and cognitive function in older adults. JAMA 2010; 303: 763-770.
31. Rubenfeld GD,. Does the hospital make you older faster? Am J Respir Crit Care Med 2012; 185: 796-798.