Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): Impact of the inter-stages course on morbi-mortality and implications for management

European Journal of Surgical Oncology

Volumn 41, Issue 5, 2015, Pages 674-682

  Truant, S ^a   Scatton, O ^a   Dokmak, S ^b   Regimbeau, J M ^c   Lucidi, V ^d   Laurent, A ^e   Gauzolino, R ^f   Castro Benitez, C ^h   Pequignot, A ^c   Donckier, V ^d   Lim, C ^e   Blanleuil, M L ^f   Brustia, R ^a   Le Treut, Y P ⁱ   Soubrane, O ^a   Azoulay, D ^e   Farges, O ^b   Adam, R ^g   Pruvot, F R ^a  

^a UNIV LILLE   (France)

^b HÔPITAL SAINT ANTOINE   (France)

^c BEAUJON HOSPITAL   (France)

^d AMIENS UNIVERSITY HOSPITAL   (France)

^e ERASME HOSPITAL   (Belgium)

^f HENRI MONDOR HOSPITAL   (France)

^g POITIERS UNIVERSITY HOSPITAL   (France)

^h HÔPITAL PAUL BROUSSE   (France)

ⁱ AIX MARSEILLE UNIVERSITY   (France)

Author keywords

ALPPS; Liver regeneration; Morbi mortality; Remnant liver; Two stage hepatectomy

Indexed keywords

ADULT; AGED; ARTICLE; ARTIFICIAL EMBOLISM; ASCITES; ASSOCIATING LIVER PARTITION AND PORTAL VEIN LIGATION FOR STAGED HEPATECTOMY; BILE DUCT FISTULA; COLORECTAL LIVER METASTASIS; CYTOLYSIS; DISEASE COURSE; FEMALE; HUMAN; HYPERTROPHY; LIVER RESECTION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORBIDITY; PERIOPERATIVE PERIOD; PORTAL VEIN EMBOLIZATION; PORTAL VEIN THROMBOSIS; POSTOPERATIVE COMPLICATION; PRIMARY TUMOR; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SURGICAL MORTALITY; SURGICAL TECHNIQUE; VERY ELDERLY; ADVERSE EFFECTS; BILE DUCT NEOPLASMS; CARCINOMA; CARCINOMA, HEPATOCELLULAR; CHOLANGIOCARCINOMA; COLORECTAL TUMOR; FEASIBILITY STUDY; GALLBLADDER NEOPLASMS; INTRAHEPATIC BILE DUCT; LIGATION; LIVER; LIVER FAILURE; LIVER NEOPLASMS; MORTALITY; PATHOLOGY; PORTAL VEIN; PROCEDURES; RADIOGRAPHY; SECONDARY; TREATMENT OUTCOME;

AGED; BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; CARCINOMA; CARCINOMA, HEPATOCELLULAR; CHOLANGIOCARCINOMA; COLORECTAL NEOPLASMS; DISEASE PROGRESSION; EMBOLIZATION, THERAPEUTIC; FEASIBILITY STUDIES; FEMALE; GALLBLADDER NEOPLASMS; HEPATECTOMY; HUMANS; LIGATION; LIVER; LIVER FAILURE; LIVER NEOPLASMS; MALE; MIDDLE AGED; PORTAL VEIN; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84931425926     PISSN: 07487983     EISSN: 15322157     Source Type: Journal    
DOI: 10.1016/j.ejso.2015.01.004     Document Type: Article

References (46)

1. Schnitzbauer AA, Lang SA, Goessmann H, et al. Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for-size settings. Ann Surg 2012;255:405-14.
2. Figueras J, Belghiti J. The ALPPS approach: should we sacrifice basic therapeutic rules in the name of innovation? World J Surg 2014;38:1520-1.
3. Schadde E, Ardiles V, Slankamenac K, et al. ALPPS offers a better chance of complete resection in patients with primarily unresectable liver tumors compared with conventional-staged hepatectomies: results of a multicenter analysis. World J Surg 2014;38:1510-9.
4. Kishi Y, Abdalla EK, Chun YS, et al. Three hundred and one consecutive extended right hepatectomies: evaluation of outcome based on systematic liver volumetry. Ann Surg 2009;250:540-8.
5. Truant S, Oberlin O, Sergent G, et al. Remnant liver volume to body weight ratio > or =0.5%: a new cut-off to estimate postoperative risks after extended resection in noncirrhotic liver. J Am Coll Surg 2007;204:22-33.
6. de Baere T, Teriitehau C, Deschamps F, et al. Predictive factors for hypertrophy of the future remnant liver after selective portal vein embolization. Ann Surg Oncol 2010;17:2081-9.
7. Ferrero A, Vigano L, Polastri R, et al. Postoperative liver dysfunction and future remnant liver: where is the limit? Results of a prospective study. World J Surg 2007;31:1643-51.
8. Nadalin S, Testa G, Malago M, et al. Volumetric and functional recovery of the liver after right hepatectomy for living donation. Liver Transpl 2004;10:1024-9.
9. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 2004;240:205-13.
10. Balzan S, Belghiti J, Farges O, et al. The "50-50 criteria" on postoperative day 5: an accurate predictor of liver failure and death after hepatectomy. Ann Surg 2005;242:824-8. discussion 828-9.
11. Skrzypczyk C, Truant S, Duhamel A, et al. Relevance of the ISGLS definition of Post hepatectomy liver failure in early prediction of poor outcome after liver resection: study on 680 hepatectomies. Ann Surg 2014;260:865-70. discussion 870.
12. Conrad C, Shivathirthan N, Camerlo A, Strauss C, Gayet B. Laparoscopic portal vein ligation with in situ liver split for failed portal vein embolization. Ann Surg 2012;256:e14-5. author reply e16-7.
13. Dokmak S, Belghiti J. Which limits to the "ALPPS" approach? Ann Surg 2012;256:e6. author reply e16-7.
14. Li J, Girotti P, Konigsrainer I, Ladurner R, Konigsrainer A, Nadalin S. ALPPS in right trisectionectomy: a safe procedure to avoid postoperative liver failure? J Gastrointest Surg 2013;17:956-61.
15. Machado MA, Makdissi FF, Surjan RC. ALPPS procedure with the use of pneumoperitoneum. Ann Surg Oncol 2013;20:1491-3.
16. Sala S, Ardiles V, Ulla M, Alvarez F, Pekolj J, de Santibanes E. Our initial experience with ALPPS technique: encouraging results. Updates Surg 2012;64:167-72.
17. Nadalin S, Capobianco I, Li J, Girotti P, Konigsrainer I, Konigsrainer A. Indications and limits for associating liver partition and portal vein ligation for staged hepatectomy (ALPPS). Lessons learned from 15 cases at a single centre. Z Gastroenterol 2014;52:35-42.
18. Shirabe K, Motomura T, Takeishi K, et al. Human early liver regeneration after hepatectomy in patients with hepatocellular carcinoma: special reference to age. Scand J Surg 2013;102:101-5.
19. Zappa M, Dondero F, Sibert A, Vullierme MP, Belghiti J, Vilgrain V. Liver regeneration at day 7 after right hepatectomy: global and segmental volumetric analysis by using CT. Radiology 2009;252:426-32.
20. Truant S, Baillet C, Deshorgue AC, et al. Asymmetric kinetics of volume and function of the remnant liver after major hepatectomy: a key for postoperative morbi-mortality assessment. Presented at the European Surgical Association, Athens April 2014.
21. Tschuor C, Croome KP, Sergeant G, et al. Salvage parenchymal liver transection for patients with insufficient volume increase after portal vein occlusion - an extension of the ALPPS approach. Eur J Surg Oncol 2013;39:1230-5.
22. Shindoh J, Vauthey JN, Zimmitti G, et al. Analysis of the efficacy of portal vein embolization for patients with extensive liver malignancy and very low future liver remnant volume, including a comparison with the associating liver partition with portal vein ligation for staged hepatectomy approach. J Am Coll Surg 2013;217:126-33. discussion 133-4.
23. Hwang S, Lee SG, Ko GY, et al. Sequential preoperative ipsilateral hepatic vein embolization after portal vein embolization to induce further liver regeneration in patients with hepatobiliary malignancy. Ann Surg 2009;249:608-16.
24. Nagino M, Kanai M, Morioka A, et al. Portal and arterial embolization before extensive liver resection in patients with markedly poor functional reserve. J Vasc Interv Radiol 2000;11:1063-8.
25. Abulkhir A, Limongelli P, Healey AJ, et al. Preoperative portal vein embolization for major liver resection: a meta-analysis. Ann Surg 2008;247:49-57.
26. Azoulay D, Castaing D, Smail A, et al. Resection of nonresectable liver metastases from colorectal cancer after percutaneous portal vein embolization. Ann Surg 2000;231:480-6.
27. Broering DC, Hillert C, Krupski G, et al. Portal vein embolization vs. portal vein ligation for induction of hypertrophy of the future liver remnant. J Gastrointest Surg 2002;6:905-13. discussion 913.
28. Brouquet A, Abdalla EK, Kopetz S, et al. High survival rate after two-stage resection of advanced colorectal liver metastases: response-based selection and complete resection define outcome. J Clin Oncol 2011;29:1083-90.
29. Lam VW, Laurence JM, Johnston E, Hollands MJ, Pleass HC, Richardson AJ. A systematic review of two-stage hepatectomy in patients with initially unresectable colorectal liver metastases. HPB (Oxford) 2013;15:483-91.
30. Adam R, Laurent A, Azoulay D, Castaing D, Bismuth H. Two-stage hepatectomy: a planned strategy to treat irresectable liver tumors. Ann Surg 2000;232:777-85.
31. Wicherts DA, de Haas RJ, Andreani P, et al. Impact of portal vein embolization on long-term survival of patients with primarily unresectable colorectal liver metastases. Br J Surg 2010;97:240-50.
32. Liu H, Zhu S. Present status and future perspectives of preoperative portal vein embolization. Am J Surg 2009;197:686-90.
33. Yokoyama Y, Nagino M, Nimura Y. Mechanisms of hepatic regeneration following portal vein embolization and partial hepatectomy: a review. World J Surg 2007;31:367-74.
34. Torres OJ, Fernandes Ede S, Oliveira CV, et al. Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): the Brazilian experience. Arq Bras Cir Dig 2013;26:40-3.
35. Tsai S, Marques HP, de Jong MC, et al. Two-stage strategy for patients with extensive bilateral colorectal liver metastases. HPB (Oxford) 2010;12:262-9.
36. Farges O, Goutte N, Bendersky N, Falissard B. Incidence and risks of liver resection: an all-inclusive French nationwide study. Ann Surg 2012;256:697-704. discussion 704-5.
37. Cauchy F, Aussilhou B, Dokmak S, et al. Reappraisal of the risks and benefits of major liver resection in patients with initially unresectable colorectal liver metastases. Ann Surg 2012;256:746-52. discussion 752e4.
38. Norton L, Moore G, Eiseman B. Liver failure in the postoperative patient: the role of sepsis and immunologic deficiency. Surgery 1975;78:6-13.
39. Schneierson SS, Amsterdam D, Perlman E. Enhancement of intraperitoneal staphylococcal virulence for mice with different bile salts. Nature 1961;190:829-30.
40. Yanaga K, Kanematsu T, Takenaka K, Sugimachi K. Intraperitoneal septic complications after hepatectomy. Ann Surg 1986;203:148-52.
41. Matsumata T, Yanaga K, Shimada M, Shirabe K, Taketomi A, Sugimachi K. Occurrence of intraperitoneal septic complications after hepatic resections between 1985 and 1990. Surg Today 1995;25:49-54.
42. Allard MA, Adam R, Bucur PO, et al. Posthepatectomy portal vein pressure predicts liver failure and mortality after major liver resection on noncirrhotic liver. Ann Surg 2013;258:822-9. discussion 829-30.
43. Boleslawski E, Vibert E, Pruvot FR, et al. How relevant is peak postoperative cytolysis after an elective hepatectomy? Ann Surg 2014;260:815-20. discussion 820-811.
44. Asencio JM, Vaquero J, Olmedilla L. Garcia Sabrido JL. "Small-for-flow" syndrome: shifting the "size" paradigm. Med Hypotheses 2013;80:573-7.
45. Panis Y, McMullan DM, Emond JC. Progressive necrosis after hepatectomy and the pathophysiology of liver failure after massive resection. Surgery 1997;121:142-9.
46. Schadde E, Ardiles V, Robles-Campos R, et al. Early survival and safety of ALPPS: first report of the International ALPPS Registry. Ann Surg 2014;260:829-36. discussion 836-828.