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Volumn 25, Issue 2, 2015, Pages 177-180

Clinical observation of panniculitis in two patients with BRAF-mutated metastatic melanoma treated with a combination of a BRAF inhibitor and a MEK inhibitor

Author keywords

Adverse event; BRAF inhibition; MEK inhibition; Melanoma; Panniculitis; Targeted therapy

Indexed keywords

B RAF KINASE INHIBITOR; BETAMETHASONE VALERATE; BINIMETINIB; DABRAFENIB; ENCORAFENIB; MEFENAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PREDNISONE; TRAMETINIB; ANTINEOPLASTIC AGENT; B RAF KINASE; BENZIMIDAZOLE DERIVATIVE; BRAF PROTEIN, HUMAN; CARBAMIC ACID DERIVATIVE; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; OXIME; PYRIDONE DERIVATIVE; PYRIMIDINONE DERIVATIVE; SULFONAMIDE;

EID: 84931346333     PISSN: 11671122     EISSN: 19524013     Source Type: Journal    
DOI: 10.1684/ejd.2014.2512     Document Type: Article
Times cited : (22)

References (30)
  • 2
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review.
    • Bos JL. ras oncogenes in human cancer: a review. Cancer Res 1989; 49: 4682-9.
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 4
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with braf v600e mutation
    • Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011; 364: 2507-16.
    • (2011) N Engl J Med , vol.364 , pp. 2507-2516
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3
  • 5
    • 84863116743 scopus 로고    scopus 로고
    • Survival in braf v600mutant advanced melanoma treated with vemurafenib
    • Sosman JA, Kim KB, Schuchter L, et al. Survival in BRAF V600mutant advanced melanoma treated with vemurafenib. N Engl J Med 2012; 366: 707-14.
    • (2012) N Engl J Med , vol.366 , pp. 707-714
    • Sosman, J.A.1    Kim, K.B.2    Schuchter, L.3
  • 6
    • 84864285704 scopus 로고    scopus 로고
    • Dabrafenib in brafmutated metastatic melanoma: A multicentre, open-label, phase 3 randomised controlled trial
    • Hauschild A, Grob JJ, Demidov LV, et al. Dabrafenib in BRAFmutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet 2012; 380: 358-65.
    • (2012) Lancet , vol.380 , pp. 358-365
    • Hauschild, A.1    Grob, J.J.2    Demidov, L.V.3
  • 7
    • 84863673204 scopus 로고    scopus 로고
    • Improved survival with mek inhibition in braf-mutated melanoma
    • Flaherty KT, Robert C, Hersey P, et al. Improved survival with MEK inhibition in BRAF-mutated melanoma. N Engl J Med 2012; 367: 10714.
    • (2012) N Engl J Med , vol.367 , pp. 10714
    • Flaherty, K.T.1    Robert, C.2    Hersey, P.3
  • 8
    • 84908245075 scopus 로고    scopus 로고
    • Combined vemurafenib and cobimetinib in braf-mutated melanoma
    • Larkin J, Ascierto PA, Dréno B, et al. Combined Vemurafenib and Cobimetinib in BRAF-Mutated Melanoma. N Engl J Med 2014; 371: 1867-76.
    • (2014) N Engl J Med , vol.371 , pp. 1867-1876
    • Larkin, J.1    Ascierto, P.A.2    Dréno, B.3
  • 9
    • 84908257665 scopus 로고    scopus 로고
    • Combined braf and mek inhibition versus braf inhibition alone in melanoma
    • Long GV, Stroyakovskiy D, Gogas H, et al. Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma. N Engl J Med 2014; 371: 1877-88.
    • (2014) N Engl J Med , vol.371 , pp. 1877-1888
    • Long, G.V.1    Stroyakovskiy, D.2    Gogas, H.3
  • 10
    • 84921491301 scopus 로고    scopus 로고
    • Improved overall survival in melanoma with combined dabrafenib and trametinib
    • [Epub ahead of print]
    • Robert C, Karaszewska B, Schachter J, et al. Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib. N Engl J Med 2014 Nov 16. [Epub ahead of print].
    • (2014) N Engl J Med , vol.16
    • Robert, C.1    Karaszewska, B.2    Schachter, J.3
  • 11
    • 84906075553 scopus 로고    scopus 로고
    • Mechanism and consequences of raf kinase activation by small-molecule inhibitors
    • Holderfield M, Nagel TE, Stuart DD. Mechanism and consequences of RAF kinase activation by small-molecule inhibitors. Br J Cancer 2014; 111: 640-5.
    • (2014) Br J Cancer , vol.111 , pp. 640-645
    • Holderfield, M.1    Nagel, T.E.2    Stuart, D.D.3
  • 12
    • 84897531613 scopus 로고    scopus 로고
    • Reversible and adaptive resistance to braf(v600e) inhibition in melanoma
    • Sun C, Wang L, Huang S, et al. Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma. Nature 2014; 508: 118-22.
    • (2014) Nature , vol.508 , pp. 118-122
    • Sun, C.1    Wang, L.2    Huang, S.3
  • 13
    • 73949083834 scopus 로고    scopus 로고
    • Mek1 mutations confer resistance to mek and b-raf inhibition
    • Emery CM, Vijayendran KG, Zipser MC, et al. MEK1 mutations confer resistance to MEK and B-RAF inhibition. Proc Natl Acad Sci U S A 2009; 106: 20411-6.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 20411-20416
    • Emery, C.M.1    Vijayendran, K.G.2    Zipser, M.C.3
  • 14
    • 84884540567 scopus 로고    scopus 로고
    • Concurrent mek2 mutation and braf amplification confer resistance to braf and mek inhibitors in melanoma
    • Villanueva J, Infante JR, Krepler C, et al. Concurrent MEK2 mutation and BRAF amplification confer resistance to BRAF and MEK inhibitors in melanoma. Cell Rep 2013; 4: 1090-9.
    • (2013) Cell Rep , vol.4 , pp. 1090-1099
    • Villanueva, J.1    Infante, J.R.2    Krepler, C.3
  • 15
    • 84883894476 scopus 로고    scopus 로고
    • [adverse skin reactions induced by braf inhibitors: A systematic review]
    • Sibaud V, Lamant L, Maisongrosse V, Delord JP. [Adverse skin reactions induced by BRAF inhibitors: a systematic review]. Ann Dermatol Venereol 2013; 140: 510-20.
    • (2013) Ann Dermatol Venereol , vol.140 , pp. 510-520
    • Sibaud, V.1    Lamant, L.2    Maisongrosse, V.3    Delord, J.P.4
  • 16
    • 84868138286 scopus 로고    scopus 로고
    • Cutaneous adverse events associated with vemurafenib in patients with metastatic melanoma: Practical advice on diagnosis, prevention and management of the main treatment-related skin toxicities
    • Sinha R, Edmonds K, Newton-Bishop JA, Gore ME, Larkin J, Fearfield L. Cutaneous adverse events associated with vemurafenib in patients with metastatic melanoma: practical advice on diagnosis, prevention and management of the main treatment-related skin toxicities. Br J Dermatol 2012; 167: 987-94.
    • (2012) Br J Dermatol , vol.167 , pp. 987-994
    • Sinha, R.1    Edmonds, K.2    Newton-Bishop, J.A.3    Gore, M.E.4    Larkin, J.5    Fearfield, L.6
  • 17
    • 84875453915 scopus 로고    scopus 로고
    • Analysis of dermatologic events in vemurafenib-treated patients with melanoma
    • Lacouture ME, Duvic M, Hauschild A, et al. Analysis of dermatologic events in vemurafenib-treated patients with melanoma. Oncologist 2013; 18: 314-22.
    • (2013) Oncologist , vol.18 , pp. 314-322
    • Lacouture, M.E.1    Duvic, M.2    Hauschild, A.3
  • 18
    • 76049113589 scopus 로고    scopus 로고
    • Mitogen-activated protein/extracellular signal-regulated kinase kinase inhibition results in biphasic alteration of epidermal homeostasis with keratinocytic apoptosis and pigmentation disorders
    • Schad K, Baumann Conzett K, Zipser MC, et al. Mitogen-activated protein/extracellular signal-regulated kinase kinase inhibition results in biphasic alteration of epidermal homeostasis with keratinocytic apoptosis and pigmentation disorders. Clin Cancer Res 2010; 16: 1058-64.
    • (2010) Clin Cancer Res , vol.16 , pp. 1058-1064
    • Schad, K.1    Baumann Conzett, K.2    Zipser, M.C.3
  • 19
    • 84868224906 scopus 로고    scopus 로고
    • Combined braf and mek inhibition in melanoma with braf v600 mutations
    • Flaherty KT, Infante JR, Daud A, et al. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med 2012; 367: 1694-703.
    • (2012) N Engl J Med , vol.367 , pp. 1694-1703
    • Flaherty, K.T.1    Infante, J.R.2    Daud, A.3
  • 20
    • 84911438827 scopus 로고    scopus 로고
    • Acneiform eruptions: A common cutaneous toxicity of the mek inhibitor trametinib
    • Anforth R, Liu M, Nguyen B, et al. Acneiform eruptions: A common cutaneous toxicity of the MEK inhibitor trametinib. Australas J Dermatol 2014; 55: 250-4.
    • (2014) Australas J Dermatol , vol.55 , pp. 250-254
    • Anforth, R.1    Liu, M.2    Nguyen, B.3
  • 21
    • 84858729203 scopus 로고    scopus 로고
    • Panniculitis with arthralgia in patients with melanoma treated with selective braf inhibitors and its management
    • Zimmer L, Livingstone E, Hillen U, Dömkes S, Becker A, Schadendorf D. Panniculitis with arthralgia in patients with melanoma treated with selective BRAF inhibitors and its management. Arch Dermatol 2012; 148: 357-61.
    • (2012) Arch Dermatol , vol.148 , pp. 357-361
    • Zimmer, L.1    Livingstone, E.2    Hillen, U.3    Dömkes, S.4    Becker, A.5    Schadendorf, D.6
  • 22
    • 84866233961 scopus 로고    scopus 로고
    • Vemurafenib-induced neutrophilic panniculitis
    • Monfort JB, Pagès C, Schneider P, et al. Vemurafenib-induced neutrophilic panniculitis. Melanoma Res 2012; 22: 399-401.
    • (2012) Melanoma Res , vol.22 , pp. 399-401
    • Monfort, J.B.1    Pagès, C.2    Schneider, P.3
  • 25
    • 85047687738 scopus 로고    scopus 로고
    • Erythema nodosum-like panniculitis in patients with melanoma treated with vemurafenib
    • Sinha R, Edmonds K, Newton-Bishop J, Gore M, Larkin J, Fearfield L. Erythema nodosum-like panniculitis in patients with melanoma treated with vemurafenib. J Clin Oncol 2013; 31: e320-1.
    • (2013) J Clin Oncol , vol.31 , pp. e320-e321
    • Sinha, R.1    Edmonds, K.2    Newton-Bishop, J.3    Gore, M.4    Larkin, J.5    Fearfield, L.6
  • 26
    • 84879174963 scopus 로고    scopus 로고
    • Neutrophilic panniculitis developing after treatment of metastatic melanoma with vemurafenib
    • Kim GH, Levy A, Compoginis G. Neutrophilic panniculitis developing after treatment of metastatic melanoma with vemurafenib. J Cutan Pathol 2013; 40: 667-9.
    • (2013) J Cutan Pathol , vol.40 , pp. 667-669
    • Kim, G.H.1    Levy, A.2    Compoginis, G.3
  • 28
    • 84921554225 scopus 로고    scopus 로고
    • Braf inhibitorsinduced panniculitis: A cutaneous side effect mimicking subcutaneous melanoma metastasis
    • Chaminade A, Conte H, Jouary T, et al. BRAF inhibitorsinduced panniculitis: a cutaneous side effect mimicking subcutaneous melanoma metastasis. J Eur Acad Dermatol Venereol 2015; 29: 392-3.
    • (2015) J Eur Acad Dermatol Venereol , vol.29 , pp. 392-393
    • Chaminade, A.1    Conte, H.2    Jouary, T.3
  • 29
    • 84902155756 scopus 로고    scopus 로고
    • Panniculitis in patients treated with braf inhibitors: A case series
    • Choy B, Chou S, Anforth R, Fernández-Peñas P. Panniculitis in Patients Treated With BRAF Inhibitors: A Case Series. Am J Dermatopathol 2014; 36: 493-7.
    • (2014) Am J Dermatopathol , vol.36 , pp. 493-497
    • Choy, B.1    Chou, S.2    Anforth, R.3    Fernández-Peñas, P.4
  • 30
    • 84868112185 scopus 로고    scopus 로고
    • How cutaneous eruptions help to understand the mode of action of kinase inhibitors
    • Dummer R, Tsao H, Robert C. How cutaneous eruptions help to understand the mode of action of kinase inhibitors. Br J Dermatol 2012; 167: 965-7.
    • (2012) Br J Dermatol , vol.167 , pp. 965-967
    • Dummer, R.1    Tsao, H.2    Robert, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.