The reaction to social stress in social phobia: Discordance between physiological and subjective parameters

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Klumbies, Elisabeth ^a   Braeuer, David ^a   Hoyer, Juergen ^a   Kirschbaum, Clemens ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLASE; ANALGESIC AGENT; ANTIHISTAMINIC AGENT; CONTRACEPTIVE AGENT; HYDROCORTISONE; PROLACTIN; PROTON PUMP INHIBITOR; THYROID HORMONE; ALPHA AMYLASE SALIVA ISOENZYME;

ADULT; AMYLASE BLOOD LEVEL; AMYLASE SALIVA LEVEL; ANXIETY; ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; BIOACCUMULATION; BIOLOGICAL FUNCTIONS; BLOOD SAMPLING; CONTROLLED STUDY; ENDOCRINE FUNCTION; FEMALE; HAIR ANALYSIS; HAIR LEVEL; HEART RATE; HEART RATE VARIABILITY; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE HAIR LEVEL; HYDROCORTISONE RELEASE; HYDROCORTISONE SALIVA LEVEL; MAJOR CLINICAL STUDY; MALE; PHYSIOLOGICAL PROCESS; PROLACTIN BLOOD LEVEL; PROLACTIN SALIVA LEVEL; SALIVA ANALYSIS; SALIVA LEVEL; SELF REPORT; SOCIAL PHOBIA; SOCIAL STRESS; STANDARDIZATION; TRIER SOCIAL STRESS TEST; BLOOD; CHEMISTRY; HAIR; MENTAL STRESS; PATHOPHYSIOLOGY; PHOBIA; PHYSIOLOGY; PSYCHOLOGY; SALIVA; YOUNG ADULT;

ADULT; ANXIETY; FEMALE; HAIR; HEART RATE; HUMANS; HYDROCORTISONE; MALE; PHOBIC DISORDERS; PROLACTIN; SALIVA; SALIVARY ALPHA-AMYLASES; SELF REPORT; STRESS, PSYCHOLOGICAL; YOUNG ADULT;

EID: 84931283158     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0105670     Document Type: Article

References (58)

1. Fehm L, Pelissolo A, Furmark T, Wittchen HU (2005) Size and burden of social phobia in Europe. Eur Neuropsychopharmacol 15: 453-462. (Pubitemid 40949552)
2. Ruscio AM, Brown TA, Chiu WT, Sareen J, Stein MB, et al. (2008) Social fears and social phobia in the USA: results from the National Comorbidity Survey Replication. Psychol Med 38: 15-28. (Pubitemid 350275216)
3. American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders, fourth edition, text revision (DMS-IV-TR). Washington D.C.: American Psychiatric Association.
4. Krämer M, Seefeldt WL, Heinrichs N, Tuschen-Caffier B, Schmitz J, et al. (2012) Subjective, autonomic, and endocrine reactivity during social stress in children with social phobia. J Abnorm Child Psychol 40: 95-104.
5. Kessler RC (2003) The impairments caused by social phobia in the general population: implications for intervention. Acta Psychiatr Scand Suppl: 19-27.
6. Ulrich-Lai YM, Herman JP (2009) Neural regulation of endocrine and autonomic stress responses. Nat Rev Neurosci 10: 397-409.
7. Kudielka BM, Hellhammer D, Kirschbaum C (2007) Ten Years of Research with the Trier Social Stress Test - Revisited. In: Harmon-Jones E, Winkielman P, editors. Social Neuroscience - integrating biological and pyschological explanations of social behavior. New York: The Guildford Press.
8. Martel FL, Hayward C, Lyons DM, Sanborn K, Varady S, et al. (1999) Salivary cortisol levels in socially phobic adolescent girls. Depress Anxiety 10: 25-27. (Pubitemid 29404546)
9. Levin AP, Saoud JB, Strauman T, Gorman JM, Fyer AJ, et al. (1993) Responses of generalized and discrete social phobics during public speaking. Journal of Anxiety Disorders 7: 207-221. (Pubitemid 23256490)
10. Beaton EA, Schmidt LA, Asbaugh AR, Santesso DL, Antony MM, et al. (2006) Low salivary cortisol levels among socially anxious young adults: Preliminary evidence from a selected and a non-selected sample. Personality and Individual Differences 41: 1217-1228. (Pubitemid 44340743)
11. Edelmann RJ, Baker SR (2002) Self-reported and actual physiological responses in social phobia. Br J Clin Psychol 41: 1-14. (Pubitemid 35252123)
12. Grossman P, Wilhelm FH, Kawachi I, Sparrow D (2001) Gender differences in psychophysiological responses to speech stress among older social phobics:: congruence and incongruence between self-evaluative and cardiovascular reactions. Psychosom Med 63: 765-777. (Pubitemid 32911006)
13. Heiser NA, Turner SM, Beidel DC, Roberson-Nay R (2009) Differentiating social phobia from shyness. J Anxiety Disord 23: 469-476.
14. Furlan PM, DeMartinis N, Schweizer E, Rickels K, Lucki I (2001) Abnormal salivary cortisol levels in social phobic patients in response to acute psychological but not physical stress. Biol Psychiatry 50: 254-259. (Pubitemid 32778441)
15. Roelofs K, van Peer J, Berretty E, Jong P, Spinhoven P, et al. (2009) Hypothalamus-pituitary-adrenal axis hyperresponsiveness is associated with increased social avoidance behavior in social phobia. Biol Psychiatry 65: 336-343.
16. van West D, Claes S, Sulon J, Deboutte D (2008) Hypothalamic-pituitary- adrenal reactivity in prepubertal children with social phobia. J Affect Disord 111: 281-290.
17. Condren RM, O'Neill A, Ryan MC, Barrett P, Thakore JH (2002) HPA axis response to a psychological stressor in generalised social phobia. Psychoneuroendocrinology 27: 693-703. (Pubitemid 34655720)
18. Beidel DC, Turner SM, Dancu CV (1985) Physiological, cognitive and behavioral aspects of social anxiety. Behav Res Ther 23: 109-117. (Pubitemid 15103232)
19. Gerlach AL, Wilhelm FH, Gruber K, Roth WT (2001) Blushing and physiological arousability in social phobia. J Abnorm Psychol 110: 247-258. (Pubitemid 32423030)
20. Schmitz J, Kramer M, Tuschen-Caffier B, Heinrichs N, Blechert J (2011) Restricted autonomic flexibility in children with social phobia. J Child Psychol Psychiatry 52: 1203-1211.
21. Chong RY, Uhart M, McCaul ME, Johnson E, Wand GS (2008) Whites have a more robust hypothalamic-pituitary-adrenal axis response to a psychological stressor than blacks. Psychoneuroendocrinology 33: 246-254.
22. Kirschbaum C, Pirke KM, Hellhammer DH (1993) The 'Trier Social Stress Test' - a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology 28: 76-81. (Pubitemid 23283755)
23. Lennartsson AK, Jonsdottir IH (2011) Prolactin in response to acute psychosocial stress in healthy men and women. Psychoneuroendocrinology 36: 1530-1539.
24. Gerra G, Zaimovic A, Mascetti GG, Gardini S, Zambelli U, et al. (2001) Neuroendocrine responses to experimentally-induced psychological stress in healthy humans. Psychoneuroendocrinology 26: 91-107.
25. Steudte S, Kirschbaum C, Gao W, Alexander N, Schonfeld S, et al. (2013) Hair cortisol as a biomarker of traumatization in healthy individuals and posttraumatic stress disorder patients. Biol Psychiatry 74: 639-646.
26. Potts NL, Davidson JR, Krishnan KR, Doraiswamy PM, Ritchie JC (1991) Levels of urinary free cortisol in social phobia. J Clin Psychiatry 52 Suppl: 41-42.
27. Uhde TW, Tancer ME, Gelernter CS, Vittone BJ (1994) Normal urinary free cortisol and postdexamethasone cortisol in social phobia: comparison to normal volunteers. J Affect Disord 30: 155-161.
28. van Veen JF, van Vliet IM, DeRijk RH, van Pelt J, Mertens B, et al. (2008) Elevated alpha-amylase but not cortisol in generalized social anxiety disorder. Psychoneuroendocrinology 33: 1313-1321.
29. Kudielka BM, Buske-Kirschbaum A, Hellhammer DH, Kirschbaum C (2004) Differential heart rate reactivity and recovery after psychosocial stress (TSST) in healthy children, younger adults, and elderly adults: the impact of age and gender. Int J Behav Med 11: 116-121. (Pubitemid 39093269)
30. Kudielka BM, Buske-Kirschbaum A, Hellhammer DH, Kirschbaum C (2004) HPA axis responses to laboratory psychosocial stress in healthy elderly adults, younger adults, and children: impact of age and gender. Psychoneuroendocrinology 29: 83-98. (Pubitemid 37303960)
31. Strahler J, Mueller A, Rosenloecher F, Kirschbaum C, Rohleder N (2010) Salivary alpha-amylase stress reactivity across different age groups. Psychophysiology 47: 587-595.
32. Yoon KL, Joormann J (2012) Stress reactivity in social anxiety disorder with and without comorbid depression. J Abnorm Psychol 121: 250-255.
33. Wittchen H-U, Pfister H (1997) Informationsmaterial zur Durchführung von DIA-X-Interviews. Frankfurt: Swets & Zeitlinger bv.
34. Stangier U, Heidenreich T (2005) LSAS Liebowitz Social Anxiety Scale. In: (CIPS) CIPS, editor. Internationale Skalen für Psychiatrie. Göttingen: Hogrefe. pp. 299-306.
35. Wittchen H-U, Perkonigg A (1997) DIA-X Screening Verfahren: Fragebogen DIA-SSQ: Screening für psychische Störungen; Fragebogen DIA-ASQ: Screening für Angststörungen; Fragebogen DIA-DSQ: Screening für Depressionen. Frankfurt: Swets & Zeitlinger bv.
36. Wennig R (2000) Potential problems with the interpretation of hair analysis results. Forensic Sci Int 107: 5-12.
37. Stalder T, Steudte S, Miller R, Skoluda N, Dettenborn L, et al. (2012) Intraindividual stability of hair cortisol concentrations. Psychoneuroendocrinology 37: 602-610.
38. Rohleder N, Nater UM (2009) Determinants of salivary alpha-amylase in humans and methodological considerations. Psychoneuroendocrinology 34: 469-485.
39. Penttila J, Helminen A, Jartti T, Kuusela T, Huikuri HV, et al. (2001) Time domain, geometrical and frequency domain analysis of cardiac vagal outflow: effects of various respiratory patterns. Clin Physiol 21: 365-376. (Pubitemid 32487594)
40. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology (1996) Heart rate variability: Standards of measurement, physiological interpretation and clinical use. Circulation 93: 1043-1065.
41. Fydrich T (2002) SPAI - Soziale Phobie und Angst Inventar. In: Brähler E, Schumacher J, Strauß B, editors. Diagnostische Verfahren in der Psychotherapie. Göttingen: Hogrefe. pp. 335-338.
42. Hautzinger M, Keller F, Kühner C (2006) Beck Depressions-Inventar (BDI-II). Revision. Frankfurt/Main: Harcourt Test Services.
43. Weyers P, Krebs H, Janke W (1995) Reliability and construct validity of the German version of Cloninger's Tridimensional Personality Questionnaire. Personality and Individual Differences 19: 853-861.
44. Reiss S, Peterson RA, Gursky DM, McNally RJ (1986) Anxiety sensitivity, anxiety frequency and the prediction of fearfulness. Behav Res Ther 24: 1-8. (Pubitemid 16207745)
45. Gaab J, Rohleder N, Nater UM, Ehlert U (2005) Psychological determinants of the cortisol stress response: the role of anticipatory cognitive appraisal. Psychoneuroendocrinology 30: 599-610. (Pubitemid 40461795)
46. Steyer R, Schwenkmezger P, Notz P, Eid M (1997) Der Mehrdimensionale Befindlichkeitsfragebogen (MDBF). Handanweisung. Göttingen: Hogrefe.
47. Laux L, Glanzmann P, Schaffner P, Spielberger CD (1981) Das State-Trait-Angstinventar. Theoretische Grundlagen und Handanweisung. Weinheim: Beltz Testgesellschaft.
48. Fehm L, Hoyer J, Schneider G, Lindemann C, Klusmann U (2008) Assessing post-event processing after social situations: a measure based on the cognitive model for social phobia. Anxiety Stress Coping 21: 129-142.
49. Gentle JE (2004) Handbook of computational statistics/concepts and methods. Berlin: Springer.
50. Lang PJ, McTeague LM (2009) The anxiety disorder spectrum: Fear imagery, physiological reactivity, and differential diagnosis. Anxiety Stress & Coping 22: 5-25.
51. Gerlach AL, Wilhelm FH, Roth WT (2003) Embarrassment and social phobia: the role of parasympathetic activation. J Anxiety Disord 17: 197-210. (Pubitemid 36279496)
52. Lorberbaum JP, Kose S, Johnson MR, Arana GW, Sullivan LK, et al. (2004) Neural correlates of speech anticipatory anxiety in generalized social phobia. Neuroreport 15: 2701-2705. (Pubitemid 40070977)
53. Clark DM, Wells A (1995) A cognitive model of social phobia; Heimberg RG, Liebowitz M, Hope DA, Schneier F, editors. New York, London: The Guilford Press. 69-93 p.
54. van Veen JF, van Vliet IM, Derijk RH, van Pelt J, Mertens B, et al. (2008) Elevated alpha-amylase but not cortisol in generalized social anxiety disorder. Psychoneuroendocrinology 33: 1313-1321.
55. Anderson ER, Hope DA (2009) The relationship among social phobia, objective and perceived physiological reactivity, and anxiety sensitivity in an adolescent population. J Anxiety Disord 23: 18-26.
56. Thibodeau MA, Gomez-Perez L, Asmundson GJ (2012) Objective and perceived arousal during performance of tasks with elements of social threat: the influence of anxiety sensitivity. J Behav Ther Exp Psychiatry 43: 967-974.
57. Beatty MJ, Behnke RR (1991) Effects of public speaking trait anxiety and intensity of speaking task on heart rate during performance. Human Communication Research 18: 147-176.
58. Rapee RM, Heimberg RG (1997) A cognitive-behavioral model of anxiety in social phobia. Behaviour Research and Therapy 35: 741-756. (Pubitemid 27336908)