Idiopathic pneumonia syndrome after hematopoietic cell transplantation: Evidence of occult infectious etiologies

Blood

Volumn 125, Issue 24, 2015, Pages 3789-3797

  Seo, Sachiko ^a   Renaud, Christian ^b   Kuypers, Jane M ^a,c   Chiu, Charles Y ^d   Huang, Meei Li ^a,c   Samayoa, Erik ^d   Xie, Hu ^a   Yu, Guixia ^d   Fisher, Cynthia E ^a,e   Gooley, Ted A ^a   Miller, Steven ^d   Hackman, Robert C ^a,c   Myerson, David ^a,c   Sedlak, Ruth H ^c   Kim, Yae Jean ^f   Fukuda, Takahiro ^g   Fredricks, David N ^a,e   Madtes, David K ^a,e   Jerome, Keith R ^a,c   Boeckh, Michael ^a,e  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^f Sungkyunkwan University School of Medicine   (South Korea)

^g National Cancer Research Center Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GALACTOMANNAN;

ADULT; ARTICLE; ASPERGILLUS; CONTROLLED STUDY; CYTOMEGALOVIRUS; FEMALE; FUNGAL DETECTION; GRAFT RECIPIENT; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN HERPESVIRUS 6; HUMAN RHINOVIRUS; IDIOPATHIC PNEUMONIA SYNDROME; LUNG LAVAGE; MAJOR CLINICAL STUDY; MALE; METAGENOMICS; MICROORGANISM DETECTION; MORTALITY; NEXT GENERATION SEQUENCING; PATHOGEN LOAD; PATHOGENICITY; PNEUMONIA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SURVIVAL; VIRUS DETECTION; ADOLESCENT; ADVERSE EFFECTS; ASPERGILLOSIS; BACTERIAL INFECTIONS; BRONCHOALVEOLAR LAVAGE FLUID; CHILD; COHORT ANALYSIS; ISOLATION AND PURIFICATION; LUNG; LUNG INJURY; MICROBIOLOGY; MIDDLE AGED; VIROLOGY; VIRUS DISEASES; YOUNG ADULT;

ADOLESCENT; ADULT; ASPERGILLOSIS; ASPERGILLUS; BACTERIAL INFECTIONS; BRONCHOALVEOLAR LAVAGE FLUID; CHILD; COHORT STUDIES; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; LUNG; LUNG INJURY; MALE; MIDDLE AGED; VIRUS DISEASES; YOUNG ADULT;

EID: 84931274921     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-12-617035     Document Type: Article

References (41)

1. Clark JG, Hansen JA, Hertz MI, Parkman R, Jensen L, Peavy HH. NHLBI workshop summary. Idiopathic pneumonia syndrome after bone marrow transplantation. Am Rev Respir Dis. 1993;147(6, pt 1):1601-1606.
2. Panoskaltsis-Mortari A, Griese M, Madtes DK, et al American Thoracic Society Committee on Idiopathic Pneumonia Syndrome. An official American Thoracic Society research statement: noninfectious lung injury after hematopoietic stem cell transplantation: idiopathic pneumonia syndrome. Am J Respir Crit Care Med. 2011;183(9):1262-1279.
3. Fukuda T, Hackman RC, Guthrie KA, et al. Risks and outcomes of idiopathic pneumonia syndrome after nonmyeloablative and conventional conditioning regimens for allogeneic hematopoietic stem cell transplantation. Blood. 2003;102(8):2777-2785.
4. Sano H, Kobayashi R, Iguchi A, et al. Risk factor analysis of idiopathic pneumonia syndrome after allogeneic hematopoietic SCT in children. Bone Marrow Transplant. 2014;49(1):38-41.
5. Sakaguchi H, Takahashi Y, Watanabe N, et al. Incidence, clinical features, and risk factors of idiopathic pneumonia syndrome following hematopoietic stem cell transplantation in children. Pediatr Blood Cancer. 2012;58(5):780-784.
6. Zhu KE, Hu JY, Zhang T, Chen J, Zhong J, Lu YH. Incidence, risks, and outcome of idiopathic pneumonia syndrome early after allogeneic hematopoietic stem cell transplantation. Eur J Haematol. 2008;81(6):461-466.
7. Keates-Baleeiro J, Moore P, Koyama T, Manes B, Calder C, Frangoul H. Incidence and outcome of idiopathic pneumonia syndrome in pediatric stem cell transplant recipients. Bone Marrow Transplant. 2006;38(4):285-289.
8. Kantrow SP, Hackman RC, Boeckh M, Myerson D, Crawford SW. Idiopathic pneumonia syndrome: changing spectrum of lung injury after marrow transplantation. Transplantation. 1997;63(8):1079-1086.
9. Yanik GA, Horowitz MM, Weisdorf DJ, et al. Randomized, double-blind, placebo-controlled trial of soluble tumor necrosis factor receptor: Enbrel (etanercept) for the treatment of idiopathic pneumonia syndrome after allogeneic stem cell transplantation: blood and marrow transplant clinical trials network protocol. Biol Blood Marrow Transplant. 2014;20(6):858-864.
10. Tizon R, Frey N, Heitjan DF, et al. High-dose corticosteroids with or without etanercept for the treatment of idiopathic pneumonia syndrome after allo-SCT. Bone Marrow Transplant. 2012;47(10):1332-1337.
11. Yanik GA, Ho VT, Levine JE, et al. The impact of soluble tumor necrosis factor receptor etanercept on the treatment of idiopathic pneumonia syndrome after allogeneic hematopoietic stem cell transplantation. Blood. 2008;112(8):3073-3081.
12. Solh M, Arat M, Cao Q, Majhail NS, Weisdorf D. Late-onset noninfectious pulmonary complications in adult allogeneic hematopoietic cell transplant recipients. Transplantation. 2011;91(7):798-803.
13. van den Hoogen BG, de Jong JC, Groen J, et al. A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med. 2001;7(6):719-724.
14. Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med. 2012;367(19):1814-1820.
15. Slavin MA, Gooley TA, Bowden RA. Prediction of cytomegalovirus pneumonia after marrow transplantation from cellular characteristics and cytomegalovirus culture of bronchoalveolar lavage fluid. Transplantation. 1994;58(8):915-919.
16. Nichols WG, Corey L, Gooley T, Davis C, Boeckh M. Parainfluenza virus infections after hematopoietic stem cell transplantation: risk factors, response to antiviral therapy, and effect on transplant outcome. Blood. 2001;98(3):573-578.
17. Fisher CE, Stevens AM, Leisenring W, Pergam SA, Boeckh M, Hohl TM. The serum galactomannan index predicts mortality in hematopoietic stem cell transplant recipients with invasive aspergillosis. Clin Infect Dis. 2013;57(7):1001-1004.
18. Sedlak RH, Cook L, Huang ML, et al. Identification of chromosomally integrated human herpesvirus 6 by droplet digital PCR. Clin Chem. 2014;60(5):765-772.
19. Wilson MR, Naccache SN, Samayoa E, et al. Actionable diagnosis of neuroleptospirosis by next-generation sequencing. N Engl J Med. 2014;370(25):2408-2417.
20. Greninger AL, Chen EC, Sittler T, et al. A metagenomic analysis of pandemic influenza A (2009 H1N1) infection in patients from North America. PLoS ONE. 2010;5(10):e13381.
21. Naccache SN, Federman S, Veeraraghavan N, et al. A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from nextgeneration sequencing of clinical samples. Genome Res. 2014;24(7):1180-1192.
22. Renaud C, Campbell AP. Changing epidemiology of respiratory viral infections in hematopoietic cell transplant recipients and solid organ transplant recipients. Curr Opin Infect Dis. 2011;24(4):333-343.
23. Bauer CC, Jaksch P, Aberle SW, et al. Relationship between cytomegalovirus DNA load in epithelial lining fluid and plasma of lung transplant recipients and analysis of coinfection with Epstein-Barr virus and human herpesvirus 6 in the lung compartment. J Clin Microbiol. 2007;45(2):324-328.
24. Costa C, Delsedime L, Solidoro P, et al. Herpesviruses detection by quantitative real-time polymerase chain reaction in bronchoalveolar lavage and transbronchial biopsy in lung transplant: viral infections and histopathological correlation. Transplant Proc. 2010;42(4):1270-1274.
25. Ison MG, Hayden FG, Kaiser L, Corey L, Boeckh M. Rhinovirus infections in hematopoietic stem cell transplant recipients with pneumonia. Clin Infect Dis. 2003;36(9):1139-1143.
26. Abandeh FI, Lustberg M, Devine S, Elder P, Andritsos L, Martin SI. Outcomes of hematopoietic SCT recipients with rhinovirus infection: a matched, case-control study. Bone Marrow Transplant. 2013;48(12):1554-1557.
27. Seo S, Campbell AP, Xie H, et al. Outcome of respiratory syncytial virus lower respiratory tract disease in hematopoietic cell transplant recipients receiving aerosolized ribavirin: significance of stem cell source and oxygen requirement. Biol Blood Marrow Transplant. 2013;19(4):589-596.
28. Schmidt GM, Horak DA, Niland JC, Duncan SR, Forman SJ, Zaia JA; The City of Hope - Stanford - Syntex CMV Study Group. A randomized, controlled trial of prophylactic ganciclovir for cytomegalovirus pulmonary infection in recipients of allogeneic bone marrow transplants. N Engl J Med. 1991;324(15):1005-1011.
29. Carrigan DR, Drobyski WR, Russler SK, Tapper MA, Knox KK, Ash RC. Interstitial pneumonitis associated with human herpesvirus-6 infection after marrow transplantation. Lancet. 1991;338(8760):147-149.
30. Cone RW, Hackman RC, Huang ML, et al. Human herpesvirus 6 in lung tissue from patients with pneumonitis after bone marrow transplantation. N Engl J Med. 1993;329(3):156-161.
31. Buchbinder S, Elmaagacli AH, Schaefer UW, Roggendorf M. Human herpesvirus 6 is an important pathogen in infectious lung disease after allogeneic bone marrow transplantation. Bone Marrow Transplant. 2000;26(6):639-644.
32. Ghosh S, Champlin R, Couch R, et al. Rhinovirus infections in myelosuppressed adult blood and marrow transplant recipients. Clin Infect Dis. 1999;29(3):528-532.
33. Gutman JA, Peck AJ, Kuypers J, Boeckh M. Rhinovirus as a cause of fatal lower respiratory tract infection in adult stem cell transplantation patients: a report of two cases. Bone Marrow Transplant. 2007;40(8):809-811.
34. Okamoto H. TT viruses in animals. Curr Top Microbiol Immunol. 2009;331:35-52.
35. Kanda Y, Tanaka Y, Kami M, et al. TT virus in bone marrow transplant recipients. Blood. 1999;93(8):2485-2490.
36. Wootton SC, Kim DS, Kondoh Y, et al. Viral infection in acute exacerbation of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2011;183(12):1698-1702.
37. Yanik G, Kitko C. Management of noninfectious lung injury following hematopoietic cell transplantation. Curr Opin Oncol. 2013;25(2):187-194.
38. Seo S, Xie H, Campbell AP, et al. Parainfluenza virus lower respiratory tract disease after hematopoietic cell transplant: viral detection in the lung predicts outcome. Clin Infect Dis. 2014;58(10):1357-1368.
39. Renaud C, Xie H, Seo S, et al. Mortality rates of human metapneumovirus and respiratory syncytial virus lower respiratory tract infections in hematopoietic cell transplantation recipients. Biol Blood Marrow Transplant. 2013;19(8):1220-1226.
40. Cordonnier C, Ribaud P, Herbrecht R, et al Société Françaisede Greffede Moelleetde Thérapie Cellulaire. Prognostic factors for death due to invasive aspergillosis after hematopoietic stem cell transplantation: a 1-year retrospective study of consecutive patients at French transplantation centers. Clin Infect Dis. 2006;42(7):955-963.
41. Baddley JW, Andes DR, Marr KA, et al. Factors associated with mortality in transplant patients with invasive aspergillosis. Clin Infect Dis. 2010;50(12):1559-1567.