메뉴 건너뛰기




Volumn 7, Issue MAY, 2015, Pages

Uncertainties in pentose-phosphate pathway flux assessment underestimate its contribution to neuronal glucose consumption: Relevance for neurodegeneration and aging

Author keywords

13C NMR spectroscopy; Aging neuroscience; Astrocyte neuron interactions; Glycolysis; Pentose phosphate pathway

Indexed keywords

CARBON 13; FRUCTOSE 6 PHOSPHATE; GLUCOSE 6 PHOSPHATE; GLYCERALDEHYDE 3 PHOSPHATE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRANSALDOLASE;

EID: 84931273224     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2015.00089     Document Type: Note
Times cited : (43)

References (29)
  • 1
    • 1342310736 scopus 로고    scopus 로고
    • Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway
    • Almeida, A., Moncada, S., and Bolaños, J. P. (2004). Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway. Nat. Cell Biol. 6, 45-51. doi: 10.1038/ncb1080
    • (2004) Nat. Cell Biol. , vol.6 , pp. 45-51
    • Almeida, A.1    Moncada, S.2    Bolaños, J.P.3
  • 3
    • 0029910556 scopus 로고
    • Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione
    • Bolaños, J. P., Heales, S. J., Peuchen, S., Barker, J. E., Land, J. M., and Clark, J. B. (1995). Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione. Free Radic. Biol. Med. 21, 995-1001.
    • (1995) Free Radic. Biol. Med. , vol.21 , pp. 995-1001
    • Bolaños, J.P.1    Heales, S.J.2    Peuchen, S.3    Barker, J.E.4    Land, J.M.5    Clark, J.B.6
  • 6
    • 33748896023 scopus 로고    scopus 로고
    • Competition between glucose and lactate as oxidative energy substrates in both neurons and astrocytes: a comparative NMR study
    • Bouzier-Sore, A. K., Voisin, P., Bouchaud, V., Bezancon, E., Franconi, J. M., and Pellerin, L. (2006). Competition between glucose and lactate as oxidative energy substrates in both neurons and astrocytes: a comparative NMR study. Eur. J. Neurosci. 24, 1687-1694. doi: 10.1111/j.1460-9568.2006.05056.x
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 1687-1694
    • Bouzier-Sore, A.K.1    Voisin, P.2    Bouchaud, V.3    Bezancon, E.4    Franconi, J.M.5    Pellerin, L.6
  • 9
    • 84883053304 scopus 로고    scopus 로고
    • Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: implications for diagnostic and therapeutic strategies
    • Chen, Z., and Zhong, C. (2013). Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: implications for diagnostic and therapeutic strategies. Progr. Neurobiol. 108, 21-43. doi: 10.1016/j.pneurobio.2013.06.004
    • (2013) Progr. Neurobiol. , vol.108 , pp. 21-43
    • Chen, Z.1    Zhong, C.2
  • 10
    • 0031800050 scopus 로고    scopus 로고
    • Ontogeny and cellular localization of the pyruvate recycling system in rat brain
    • Cruz, F., Scott, S. R., Barroso, I., Santisteban, P., and Cerdán, S. (1998). Ontogeny and cellular localization of the pyruvate recycling system in rat brain. J. Neurochem. 70, 2613-2619.
    • (1998) J. Neurochem. , vol.70 , pp. 2613-2619
    • Cruz, F.1    Scott, S.R.2    Barroso, I.3    Santisteban, P.4    Cerdán, S.5
  • 11
    • 84900923605 scopus 로고    scopus 로고
    • Pentose phosphate pathway and NADPH metabolism
    • Neural Energy Utilization, eds G Dienel and G. Gibson (Heidelberg: Springer)
    • Dringen, R., Hoepken, H. H., Minich, T., and Ruedig, C. (2007). "Pentose phosphate pathway and NADPH metabolism." in Handbook of Neurochemistry and Molecular Neurobiology, Vol. 5., Neural Energy Utilization, eds G. Dienel and G. Gibson (Heidelberg: Springer), 41-62.
    • (2007) Handbook of Neurochemistry and Molecular Neurobiology , vol.5 , pp. 41-62
    • Dringen, R.1    Hoepken, H.H.2    Minich, T.3    Ruedig, C.4
  • 13
    • 0024536465 scopus 로고
    • Effect of 6-phosphogluconate on phosphoglucose isomerase in rat brain in vitro and in vivo
    • Gaitonde, M. K., Murray, E., and Cunningham, V. J. (1989). Effect of 6-phosphogluconate on phosphoglucose isomerase in rat brain in vitro and in vivo. J. Neurochem. 52, 1348-1352. doi: 10.1111/j.1471-4159.1989.tb09178.x
    • (1989) J. Neurochem. , vol.52 , pp. 1348-1352
    • Gaitonde, M.K.1    Murray, E.2    Cunningham, V.J.3
  • 14
    • 0037428488 scopus 로고    scopus 로고
    • Peroxynitrite protects neurons against nitric oxide-mediated apoptosis A key role for glucose-6-phosphate dehydrogenase activity in neuroprotection
    • Garcia-Nogales, P., Almeida, A., and Bolaños, J. P. (2003). Peroxynitrite protects neurons against nitric oxide-mediated apoptosis. A key role for glucose-6-phosphate dehydrogenase activity in neuroprotection. J. Biol. Chem. 278, 864-874. doi: 10.1074/jbc.M206835200
    • (2003) J. Biol. Chem. , vol.278 , pp. 864-874
    • Garcia-Nogales, P.1    Almeida, A.2    Bolaños, J.P.3
  • 15
    • 0035024367 scopus 로고    scopus 로고
    • 3H]glucose overestimates glycolytic flux in isolated working rat heart: role of the pentose phosphate pathway
    • 3H]glucose overestimates glycolytic flux in isolated working rat heart: role of the pentose phosphate pathway. Am. J. Physiol. Endocrinol. Metab. 280, E502-E508.
    • (2001) Am. J. Physiol. Endocrinol. Metab. , vol.280 , pp. E502-E508
    • Goodwin, G.W.1    Cohen, D.M.2    Taegtmeyer, H.3
  • 16
    • 67349249403 scopus 로고    scopus 로고
    • The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1
    • Herrero-Mendez, A., Almeida, A., Fernandez, E., Maestre, C., Moncada, S., and Bolaños, J. P. (2009). The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1. Nat. Cell Biol. 11: 747-752. doi: 10.1038/ncb1881
    • (2009) Nat. Cell Biol. , vol.11 , pp. 747-752
    • Herrero-Mendez, A.1    Almeida, A.2    Fernandez, E.3    Maestre, C.4    Moncada, S.5    Bolaños, J.P.6
  • 17
    • 0018631195 scopus 로고
    • Alternative pathways of glucose utilization in brain Changes in the pattern of glucose utilization in brain during development and the effect of phenazine methosulphate on the integration of metabolic routes
    • Hothersall, J. S., Baquer, N. Z., Greenbaum, A. L., and McLean, P. (1979). Alternative pathways of glucose utilization in brain. Changes in the pattern of glucose utilization in brain during development and the effect of phenazine methosulphate on the integration of metabolic routes. Arch. Biochem. Biophys. 198, 478-492. doi: 10.1016/0003-9861(79)90522-8
    • (1979) Arch. Biochem. Biophys. , vol.198 , pp. 478-492
    • Hothersall, J.S.1    Baquer, N.Z.2    Greenbaum, A.L.3    McLean, P.4
  • 18
    • 84920640012 scopus 로고    scopus 로고
    • Glycolysis and the pentose phosphate pathway after human traumatic brain injury: microdialysis studies using 1 2-(13)C2 glucose
    • Jalloh, I., Carpenter, K. L., Grice, P., Howe, D. J., Mason, A., Gallagher, C. N., et al. (2015). Glycolysis and the pentose phosphate pathway after human traumatic brain injury: microdialysis studies using 1,2-(13)C2 glucose. J. Cereb. Blood Flow Metab. 35, 111-120. doi: 10.1038/jcbfm.2014.177
    • (2015) J. Cereb. Blood Flow Metab. , vol.35 , pp. 111-120
    • Jalloh, I.1    Carpenter, K.L.2    Grice, P.3    Howe, D.J.4    Mason, A.5    Gallagher, C.N.6
  • 20
    • 0345978513 scopus 로고
    • Isotope discrimination effects in the metabolism of tritiated glucose
    • Katz, J., Rognstad, R., and Kemp, R. G. (1965). Isotope discrimination effects in the metabolism of tritiated glucose. J. Biol. Chem. 240, PC1484-PC1486.
    • (1965) J. Biol. Chem. , vol.240 , pp. PC1484-PC1486
    • Katz, J.1    Rognstad, R.2    Kemp, R.G.3
  • 21
    • 0024416044 scopus 로고
    • 2 data, with applications to peripheral ganglia of chicken embryos
    • 2 data, with applications to peripheral ganglia of chicken embryos. J. Biol. Chem. 264, 15875-15879.
    • (1989) J. Biol. Chem. , vol.264 , pp. 15875-15879
    • Larrabee, M.G.1
  • 22
    • 0033982623 scopus 로고    scopus 로고
    • Mitochondrial malic enzyme activity is much higher in mitochondria from cortical synaptic terminals compared with mitochondria from primary cultures of cortical neurons or cerebellar granule cells
    • McKenna, M. C., Stevenson, J. H., Huang, X., Tildon, J. T., Zielke, C. L., and Hopkins, I. B. (2000). Mitochondrial malic enzyme activity is much higher in mitochondria from cortical synaptic terminals compared with mitochondria from primary cultures of cortical neurons or cerebellar granule cells. Neurochem. Int. 36, 451-459. doi: 10.1016/S0197-0186(99)00148-5
    • (2000) Neurochem. Int. , vol.36 , pp. 451-459
    • McKenna, M.C.1    Stevenson, J.H.2    Huang, X.3    Tildon, J.T.4    Zielke, C.L.5    Hopkins, I.B.6
  • 23
    • 0015349584 scopus 로고
    • The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart
    • Neely, J. R., Denton, R. M., England, P. J., and Randle, P. J. (1972). The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart. Biochem. J. 128, 147-159.
    • (1972) Biochem. J. , vol.128 , pp. 147-159
    • Neely, J.R.1    Denton, R.M.2    England, P.J.3    Randle, P.J.4
  • 24
    • 33947611667 scopus 로고    scopus 로고
    • Pyruvate recycling in cultured neurons from cerebellum
    • Olstad, E., Olsen, G. M., Qu, H., and Sonnewald, U. (2007). Pyruvate recycling in cultured neurons from cerebellum. J. Neurosci. Res. 85, 3318-3325. doi: 10.1002/jnr.21208
    • (2007) J. Neurosci. Res. , vol.85 , pp. 3318-3325
    • Olstad, E.1    Olsen, G.M.2    Qu, H.3    Sonnewald, U.4
  • 25
    • 0028080101 scopus 로고
    • Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization
    • Pellerin, L., and Magistretti, P. J. (1994). Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc. Natl. Acad. Sci. U.S.A. 91, 10625-10629.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 10625-10629
    • Pellerin, L.1    Magistretti, P.J.2
  • 26
    • 84889091326 scopus 로고    scopus 로고
    • Underestimation of the pentose-phosphate pathway in intact primary neurons as revealed by metabolic flux analysis
    • Rodriguez-Rodriguez, P., Fernandez, E., and Bolaños, J. P. (2013). Underestimation of the pentose-phosphate pathway in intact primary neurons as revealed by metabolic flux analysis. J. Cereb. Blood Flow Metab. 33, 1843-1845. doi: 10.1038/jcbfm.2013.168
    • (2013) J. Cereb. Blood Flow Metab. , vol.33 , pp. 1843-1845
    • Rodriguez-Rodriguez, P.1    Fernandez, E.2    Bolaños, J.P.3
  • 28
    • 0031782834 scopus 로고    scopus 로고
    • Mitochondrial malic enzyme: purification from bovine brain, generation of an antiserum, and immunocytochemical localization in neurons of rat brain
    • Vogel, R., Jennemann, G., Seitz, J., Wiesinger, H., and Hamprecht, B. (1998). Mitochondrial malic enzyme: purification from bovine brain, generation of an antiserum, and immunocytochemical localization in neurons of rat brain. J. Neurochem. 71, 844-852.
    • (1998) J. Neurochem. , vol.71 , pp. 844-852
    • Vogel, R.1    Jennemann, G.2    Seitz, J.3    Wiesinger, H.4    Hamprecht, B.5
  • 29
    • 57649178844 scopus 로고    scopus 로고
    • The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: a review
    • Wamelink, M. M., Struys, E. A., and Jakobs, C. (2008). The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: a review. J. Inherit. Metab. Dis. 31, 703-717. doi: 10.1007/s10545-008-1015-6
    • (2008) J. Inherit. Metab. Dis. , vol.31 , pp. 703-717
    • Wamelink, M.M.1    Struys, E.A.2    Jakobs, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.