Risk factors for bronchiolitis hospitalization during the first year of life in a multicenter Italian birth cohort

Italian Journal of Pediatrics

Volumn 41, Issue 1, 2015, Pages

  Lanari, Marcello ^a   Prinelli, Federica ^b,c   Adorni, Fulvio ^b   Di Santo, Simona ^d   Vandini, Silvia ^e   Silvestri, Michela ^f   Musicco, Massimo ^b,d   Faldella, G ^g   Spinelli, M ^g   Corsello, G ^g   Gabriele, B ^g   La Forgia, N ^g   Loprieno, S ^g   Boldrini, A ^g   Vuerich, M ^g   Del Vecchio, A ^g   Bertino, E ^g   Fabris, C ^g   Coscia, A ^g   Fanos, V ^g   Puddu, M ^g   Gargano, G ^g   Braibanti, S ^g   Corso, G ^g   Orfeo, L ^g   De Luca, M G ^g   Paolillo, P ^g   Fabiano, A ^g   Barberi, I ^g   Arco, A ^g   Barboni, G ^g   Molinari, L ^g   Bonomi, A ^g   Ladetto, L ^g   Carlucci, A ^g   Zorzi, G ^g   Dall'agnola A ^g   Girardi, E ^g   Di Fabio, S ^g   Faccia, P ^g   Bottau, P ^g   Macagno, F ^g   Ellero, S ^g   Magaldi, R ^g   Rinaldi, M ^g   Memo, L ^g   Nicolini, G ^g   Ngalikpima, C J ^g   Nosari, N ^g   Sarnelli, P ^g   Parmigiani, S ^g   Agosti, M ^g   Negri, C ^g   Corona, M F ^g   Piano, F ^g   Scarcella, A ^g   Umbaldo, A ^g   De Curtis, M ^g   Natale, F ^g   Aurilia, C ^g   Romagnoli, C ^g   more..

^a Imola Hospital   (Italy)

^b INSTITUTE OF BIOMEDICAL TECHNOLOGIES   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^e UNIVERSITY OF BOLOGNA   (Italy)

^f G GASLINI INSTITUTE   (Italy)

^g NONE

Author keywords

Bronchiolitis; Children; Hospitalization; Palivizumab; Prophylaxis; Respiratory syncytial virus; Risk factor

Indexed keywords

CORTICOSTEROID;

ADULT; ARTICLE; BIRTH; BREAST FEEDING; BRONCHIOLITIS; CHILD HOSPITALIZATION; CLINICAL EVALUATION; COHORT ANALYSIS; DISEASE ASSOCIATION; DRUG EFFECT; EPIDEMIC; FEMALE; FOLLOW UP; GESTATIONAL AGE; HUMAN; ITALIAN (CITIZEN); ITALY; MAJOR CLINICAL STUDY; MALE; MATERNAL SMOKING; NEWBORN; PRENATAL EXPOSURE; RISK FACTOR; SIBLING; BRONCHIOLITIS, VIRAL; COMPLICATION; CROWDING (AREA); HOSPITALIZATION; INFANT; MULTIVARIATE ANALYSIS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; SEX DIFFERENCE; STATISTICS AND NUMERICAL DATA; VIROLOGY;

BREAST FEEDING; BRONCHIOLITIS, VIRAL; COHORT STUDIES; CROWDING; FEMALE; GESTATIONAL AGE; HOSPITALIZATION; HUMANS; INFANT; INFANT, NEWBORN; ITALY; MALE; MULTIVARIATE ANALYSIS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RISK FACTORS; SEX FACTORS;

EID: 84931260754     PISSN: 17208424     EISSN: 18247288     Source Type: Journal    
DOI: 10.1186/s13052-015-0149-z     Document Type: Article

References (44)

1. Boyce TG, Mellen BG, Mitchel EF, Wright PF, Griffin MR. Rates of hospitalization for respiratory syncytial virus infec-tion among children in medicaid. J Pediatr. 2000;137(6):865-70.
2. Leader S, Kohlhase K. Recent trends in severe respiratory syncytial virus (RSV) among US infants; 1997 to 2000. J Pediatr. 2003;143(5 Suppl):S127-32.
3. Nair H, Nokes DJ, Gessner BD, Dherani M, Madhi SA, Singletoni RJ, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet. 2010;375(9725):1545-55.
4. Hall CB, Weinberg GA, Iwane MK, Blumkin AK, Edwards KM, Staat MA, et al. The burden of respiratory syncytial virus infection in young children. N Engl J Med. 2009;360(6):588-98.
5. Thorburn K. Pre-existing disease is associated with a significantly higher risk of death in severe respiratory syncytial virus infection. Arch Dis Child. 2009;94(2):99-103.
6. Park HW, Lee BS, Kim AR, Yoon HS, Kim BI, Song ES, et al. Epidemiology of respiratory syncytial virus infection in infants born at less than thirty-five weeks of gestational age. Pediatr Infect Dis. 2012;31(8):99-104.
7. Liese JG, Grill E, Fischer B, Roeckl-Wiedmann I, Carr D, Belohradsky BH. Incidence and risk factors of respiratory syncytial virus-related hospitalizations in premature infants in Germany. Eur J Pediatr. 2003;162:230-6.
8. Carbonell-Estrany X, Figueras-Aloy J, Law BJ. Infección Respiratoria Infantil por Virus Respiratorio Sincitial Study Group; Pediatric Investigators Collaborative Network on Infections in Canada Study Group. Identifying risk factors for severe respiratory syncytial virus among infants born after 33 through 35 completed weeks of gestation: different methodologies yield consistent findings. Pediatr Infect Dis J. 2004;23(11 Suppl):S193-201.
9. Horn SD, Smout RJ. Effect of prematurity on respiratory syn-cytial virus hospital resource use and outcomes. J Pediatr. 2003;143(5 Suppl):S133-41.
10. Welliver RC. Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection. J Pediatr. 2003;143(5 Suppl):S112-7.
11. Sommer C, Resch B, Simões EAF. Risk factors for severe respiratory syncytial virus lower respiratory tract infection. Open Microbio J. 2011;5((Suppl 2-M4):144-15.
12. Figueras-Aloy J, Carbonell-Estrany X, Quero-Jiménez J, et al. FLIP-2 Study: risk factors linked to respiratory syncytial virus infection requiring hospitalization in premature infants born in Spain at a gestational age of 32 to 35 weeks. Pediatr Infect Dis J. 2008;27:788-93.
13. Figueras-Aloy J, Carbonell-Estrany X, Quero J, Group IS. Case-control study of the risk factors linked to respiratory syncytial virus infection requiring hospitalization in premature infants born at a gestational age of 33-35 weeks in Spain. Pediatr Infect Dis J. 2004;23:815-20.
14. Law B, Langley J, Allen U, Paes B, Lee DS, Mitchell I, et al. The Pediatric Investigators Collaborative Network on Infections in Canada study of predictors of hospitalization for respiratory syncytial virus infection for infants born at 33 through 35 completed weeks of gestation. Pediatr Infect Dis J. 2004;23:806-14.
15. Lanari M, Giovannini M, Giuffré L, Marini A, Rondini G, Rossi GA, et al. Prevalence of respiratory syncytial virus infection in Italian infants hospitalized for acute lower respiratory tract infections, and association between respiratory syncytial virus infection risk factors and disease severity. Ped Pulmonol. 2002;33:458-65.
16. American Academy of Pediatrics Committee on Infectious Diseases. American Academy of Pediatrics Bronchiolitis Guidelines Committee. Updated guidance for palivizumab prophylaxis among infants and young children at increased risk of hospitalization for respiratory syncytial virus infection. Pediatrics. 2014;134(2):e620-38.
17. Raccomandazioni della Società Italiana di Neonatologia per la prevenzione delle malattie da virus respiratorio sinciziale (VRS). Acta Neonatologica e Pediatrica 2004;18:19-30
18. Baraldi E, Carraro S, Filippone M. Bronchopulmonary dysplasia: definitions and long-term respiratory outcome. Early Hum Dev. 2009;85(10 Suppl):S1-3.
19. Medici MC, Arcangeletti MC, Rossi GA, Lanari M, Merolla R, Paparatti UD, et al. Osservatorio VRS Study Group. Four year incidence of respiratory syncytial virus infection in infants and young children referred to emergency departments for lower respiratory tract diseases in Italy: the 'Osservatorio VRS' Study (2000-2004). New Microbiol. 2006;29:35-43.
20. Bertino E, Spada E, Occhi L, Coscia A, Giuliani F, Gagliardi L, et al. Neonatal anthropometric charts: the Italian neonatal study compared with other European studies. J Pediatr Gastroenterol Nutr. 2010;51(3):353-61.
21. Baraldi E, Lanari M, Manzoni P, Rossi GA, Vandini S, Rimini A, et al. Inter-society consensus document on treatment and prevention of bronchiolitis in newborns and infants. Ital J Pediatr. 2014;40:65.
22. Shay DK, Holman RC, Roosevelt GE, Clarke MJ, Anderson LJ. Bronchiolitis-associated mortality and estimates of respiratory syncytial virus-associated deaths among US children; 1979-1997. J Infect Dis. 2001;183(1):16-22.
23. Simoes EAF. Environmental and demographic risk factors for respiratory syncytial virus lower respiratory tract disease. J Pediatr. 2003;143:S118-26.
24. Houben ML, Bont L, Wilbrink B, Belderbos ME, Kimpen JL, Visser GH, et al. Clinical prediction rule for RSV bronchiolitis in healthy newborns: prognostic birth cohort study. Pediatrics. 2011;127(1):35-41.
25. Kotecha SJ, Watkins WJ, Heron J, Henderson J, Dunstan FD, Kotecha S. Spirometric lung function in school-age children. Effect of intrauterine growth retardation and catch-up growth. Am J Respir Crit Care Med. 2010;181:969-74.
26. Leslie FM. Multigenerational epigenetic effects of nicotine on lung function. BMC Med. 2013;11:27.
27. Joss-Moore LA, Albertine KH, Lane RH. Epigenetics and the developmental origins of lung disease. Mol Genet Metab. 2011;104(1-2):61-6.
28. Nielsen HE, Siersma V, Andersen S, Gahrn-Hansen B, Mordhorst CH, Norgaard-Pedersen B, et al. Respiratory syncytial virus infection: risk factors for hospital admission - a case control study. Acta Paediatr. 2003;92:1314-21.
29. Resch B, Pasnocht A, Gusenleitner W, Müller W. Rehospitalisations for respiratory disease and respiratory syncytial virus infection in preterm infants of 29-36 weeks gestational age. J Infect. 2005;50(5):397-403.
30. Medlock S, Ravelli AC, Tamminga P, Mol BW, Abu-Hanna A. Prediction of mortality in very premature infants: a systematic review of prediction models. PLoS One. 2011;6(9), e23441.
31. Lanari M, Prinelli F, Adorni F, Di Santo S, Faldella G, Silvestri M, et al. Italian Neonatology Study Group on RSV Infections. Maternal milk protects infants against bronchiolitis during the first year of life. Results from an Italian cohort of newborns. Early Hum Dev. 2013;89 Suppl 1:S51-7.
32. Holberg CJ, Wright AL, Martinez FD, Ray CG, Taussig LM, Lebowitz MD. Risk factors for respiratory syncytial virus-associated lower respiratory illnesses in the first year of life. Am J Epidemiol. 1991;133(11):1135-51.
33. Bulkow LR, Singleton RJ, DeByle C, Miernyk K, Redding G, Hummel KB, et al. Risk factors for hospitalization with lower respiratory tract infections in children in rural Alaska. Pediatrics. 2012;129(5):e1220-7.
34. Hall CB, Weinberg GA, Blumkin AK, Edwards KM, Staat MA, Schultz AF, et al. Respiratory syncytial virus-associated hospitalizations among children less than 24 months of age. Pediatrics. 2013;132(2):e341-8.
35. Olabarrieta I, Gonzalez-Carrasco E, Calvo C, Pozo F, Casas I, García-García ML. Hospital admission due to respiratory viral infections in moderate preterm, late preterm and term infants during their first year of life. Allergol Immunopathol (Madr). 2014 Nov 8. doi: 10.1016/j.aller.2014.06.006.
36. Muller-Pebody B, Edmunds WJ, Zambon MC, Gay NJ, Crowcroft NS. Contribution of RSV to bronchiolitis and pneumonia-associated hospitalizations in English children, April 1995-March 1998. Epidemiol Infect. 2002;129(1):99-106.
37. Escobar GJ, Ragins A, Li SX, Prager L, Masaquel AS, Kipnis P. Recurrent wheezing in the third year of life among children born at 32 weeks' gestation or later: relationship to laboratory-confirmed, medically attended infection with respiratory syncytial virus during the first year of life. Arch Pediatr Adolesc Med. 2010;164(10):915-22.
38. Chan KN, Noble Jamieson CM, Elliman A, Bryan EM, Silverman M. Lung function in children of low birth weight. Arch Dis Child. 1989;64:1284-9.
39. Henderson J, Hilliard TN, Sherriff A, Stalker D, Al SN, Thomas HM. Hospitalization for RSV bronchiolitis before 12 months of age and subsequent asthma, atopy and wheeze: a longitudinal birth cohort study. Pediatr Allergy Immunol. 2005;16:386-92.
40. Bacharier LB, Cohen R, Schweiger T, Yin-Declue H, Christie C, Zheng J, et al. Determinants of asthma after severerespiratory syncytial virus bronchiolitis. J Allergy Clin Immunol. 2012;130:91-100.
41. Stein RT, Sherrill D, Morgan WJ, Holberg CJ, Halonen M, Taussig LM, et al. Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet. 1999;354:541-5.
42. Sigurs N, Aljassim F, Kjellman B, Robinson PD, Sigurbergsson F, Bjarnason R, et al. Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life. Thorax. 2010;65:1045-52.
43. Mai XM, Gaddlin PO, Nilsson L, Finnstrom O, Bjorksten B, Jenmalm MC. Asthma, lung function and allergy in 12-year-old children with very low birth weight: a prospective study. Pediatr Allergy Immunol. 2003;14:184-92.
44. Blanken MO, Rovers MM, Molenaar JM, Winkler-Seinstra PL, Meijer A, Kimpen JL, et al. Dutch RSV Neonatal Network. Respiratory syncytial virus and recurrent wheeze in healthy preterm infants. N Engl J Med. 2013;368(19):1791-9.