Whole finger iontophoresis of sodium nitroprusside to increase blood flow in patients with systemic sclerosis: Influence of concentration

International Journal of Pharmaceutics

Volumn 490, Issue 1-2, 2015, Pages 446-449

  Little, Jayne ^a   Murray, Andrea ^a   Dinsdale, Graham ^a   Wilkinson, Jack ^b   Moore, Tonia ^a   Herrick, Ariane L ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Concentration; Iontophoresis; Systemic sclerosis; Vasodilation

Indexed keywords

NITROPRUSSIDE SODIUM; VASODILATOR AGENT;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BLOOD FLOW; CLINICAL ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FINGER BLOOD FLOW; HUMAN; IONTOPHORESIS; LASER DOPPLER FLOWMETRY; MALE; MULTICENTER STUDY (TOPIC); PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REGRESSION ANALYSIS; SYSTEMIC SCLEROSIS; TISSUE PERFUSION; VASODILATATION; WHOLE FNGERI IONTOPHORESIS; BLOOD; CASE CONTROL STUDY; DRUG EFFECTS; FINGER; MIDDLE AGED; PATHOPHYSIOLOGY; PROCEDURES;

ADULT; AGED; CASE-CONTROL STUDIES; FEMALE; FINGERS; HUMANS; IONTOPHORESIS; LASER-DOPPLER FLOWMETRY; MALE; MIDDLE AGED; NITROPRUSSIDE; REGIONAL BLOOD FLOW; SCLERODERMA, SYSTEMIC; VASODILATION; VASODILATOR AGENTS;

EID: 84930966145     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.05.034     Document Type: Article

References (15)

1. M.E. Anderson, S. Hollis, T. Moore, M.I. Jayson, and A.L. Herrick Non-invasive assessment of vascular reactivity in forearm skin of patients with primary Raynaud's phenomenon and systemic sclerosis Br. J. Rheumatol. 35 12 1996 1281 1298
2. M.E. Anderson, F. Campbell, S. Hollis, T. Moore, M.I. Jayson, and A.L. Herrick Non-invasive assessment of digital vascular reactivity in patients with primary Raynaud's phenonenon and systemic sclerosis Clin. Exp. Rheumatol. 17 1 1999 49 54
3. L. Chung, L. Shapiro, D. Fiorentino, M. Baron, J. Shanahan, and S. Sule MQX-503, a novel formulation of nitroglycerin, improves the severity of Raynaud's phenomenon: a randomized, controlled trial Arthritis Rheum. 60 3 2009 870 877
4. S. Durand, B. Fromy, P. Bouye, J.L. Saumet, and P. Abraham Vasodilatation in response to repeated anodal current application in the human skin relies on aspirin-sensitive mechanisms J. Physiol. 540 Pt 1 2002 261 269
5. A.L. Herrick Therapy: a local approach to Raynaud phenomenon Nat. Rev. Rheumatol. 5 5 2009 246 247
6. M.E. Hettema, D. Zhang, Y. Stienstra, A.J. Smit, H. Bootsma, and C.G. Kallenberg No effects of bosentan on microvasculature in patients with limited cutaneous systemic sclerosis Clin. Rheumatol. 28 7 2009 825 833
7. D.G. Hottinger, D.S. Beebe, T. Kozhimannil, R.C. Prielipp, and K.G. Belani Sodium nitroprusside in 2014: a clinical concepts review J. Anaesthesiol. Clin. Pharmacol. 30 4 2014 462 471
8. F. Khan, and J.J. Belch Skin blood flow in patients with systemic sclerosis and Raynaud's phenomenon: effects of oral l-arginine supplementation J. Rheumatol. 26 11 1999 2389 2394
9. F. Khan, S.J. Litchfield, M. McLaren, D.J. Veale, R.C. Littleford, and J.J. Belch Oral l-arginine supplementation and cutaneous vascular responses in patients with primary Raynaud's phenomenon Arthritis Rheum. 40 2 1997 352 357
10. O. Kowal-Bielecka, R. Landewe, J. Avouac, S. Chwiesko, I. Miniati, and L. Czirjak EULAR recommendations for the treatment of systemic sclerosis: a report from the EULAR Scleroderma Trials and Research group (EUSTAR) Ann. Rheum. Dis. 68 5 2009 620 628
11. L. La Civita, M. Rossi, G. Vagheggini, F.A. Storino, L. Credidio, and G. Pasero Microvascular involvement in systemic sclerosis: laser Doppler evaluation of reactivity to acetylcholine and sodium nitroprusside by iontophoresis Ann. Rheum. Dis. 57 1 1998 52 55
12. A.K. Murray, A.L. Herrick, R.E. Gorodkin, T.L. Moore, and T.A. King Possible therapeutic use of vasodilator iontophoresis Microvasc. Res. 69 1-2 2005 89 94
13. A.K. Murray, T.L. Moore, T.A. King, and A.L. Herrick Vasodilator iontophoresis a possible new therapy for digital ischaemia in systemic sclerosis? Rheumatology 47 1 2008 76 79
14. V. Steen, C.P. Denton, J.E. Pope, and M. Matucci-Cerinic Digital ulcers: overt vascular disease in systemic sclerosis Rheumatology 48 Suppl. 3 2009 iii19 iii24
15. E. Tesselaar, and F. Sjoberg Transdermal iontophoresis as an in-vivo technique for studying microvascular physiology Microvasc. Res. 81 1 2011 88 96