Naringenin ameliorates daunorubicin induced nephrotoxicity by mitigating AT1R, ERK1/2-NFκB p65 mediated inflammation

International Immunopharmacology

Volumn 28, Issue 1, 2015, Pages 154-159

  Karuppagounder, Vengadeshprabhu ^a   Arumugam, Somasundaram ^a   Thandavarayan, Rajarajan Amirthalingam ^a,b   Pitchaimani, Vigneshwaran ^a   Sreedhar, Remya ^a   Afrin, Rejina ^a   Harima, Meilei ^a   Suzuki, Hiroshi ^a   Suzuki, Kenji ^c   Nakamura, Masahiko ^d   Ueno, Kazuyuki ^a   Watanabe, Kenichi ^a  

^a NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^b HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^c NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^d Yamanashi Prefectural Central Hospital   (Japan)

Author keywords

Angiotensin II type I receptor; Endoplasmic reticulum stress; Extracellular signal regulated kinase; Inflammation; Nephrotoxicity

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; CREATININE; DAUNORUBICIN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; EOSIN; HEMATOXYLIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NARINGENIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR RELA; ANTINEOPLASTIC ANTIBIOTIC; FLAVANONE DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; URINARY TRACT AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOWN REGULATION; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; HISTOPATHOLOGY; INVESTIGATIVE PROCEDURES; KIDNEY DYSFUNCTION; KIDNEY FIBROSIS; KIDNEY FUNCTION; KIDNEY PARENCHYMA; MALE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION; UREA NITROGEN BLOOD LEVEL; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CHEMICALLY INDUCED; DRUG EFFECTS; FIBROSIS; INFLAMMATION; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY DISEASES; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; DAUNORUBICIN; ENDOPLASMIC RETICULUM STRESS; FIBROSIS; FLAVANONES; INFLAMMATION; INJECTIONS, INTRAVENOUS; KIDNEY DISEASES; MALE; MAP KINASE SIGNALING SYSTEM; PPAR GAMMA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 1; RENAL AGENTS; TRANSCRIPTION FACTOR RELA;

EID: 84930938257     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.05.050     Document Type: Article

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