Liver MRI is more precise than liver biopsy for assessing total body iron balance: A comparison of MRI relaxometry with simulated liver biopsy results

Magnetic Resonance Imaging

Volumn 33, Issue 6, 2015, Pages 761-767

  Wood, John C ^a   Zhang, Pinggao ^b   Rienhoff, Hugh ^d   Abi Saab, Walid ^c   Neufeld, Ellis J ^e  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b Shire Pharmaceuticals   (United States)

^c Global Clinical Development   (Switzerland)

^d Ferrokin Biosciences Inc   (United States)

^e BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Iron overload; Liver; Monte Carlo Simulation; Relaxometry; Sickle cell disease; Thalassemia

Indexed keywords

DEFERITAZOLE; IRON;

ADULT; ARTICLE; BLOOD TRANSFUSION; CLINICAL ARTICLE; HUMAN; IRON BALANCE; IRON BINDING CAPACITY; IRON CHELATION; LIVER BIOPSY; LIVER IRON CONCENTRATION; LIVER LEVEL; MAGNETIC RESONANCE IMAGING RELAXOMETRY; MEASUREMENT ACCURACY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT COMPLIANCE; PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; SAMPLING ERROR; SICKLE CELL ANEMIA; SIMULATION; THALASSEMIA; ADOLESCENT; BIOPSY; CLINICAL TRIAL; COMPARATIVE STUDY; COMPUTER SIMULATION; FEMALE; IRON OVERLOAD; LIVER; MALE; MIDDLE AGED; PATHOLOGY; PHASE 2 CLINICAL TRIAL; REPRODUCIBILITY; YOUNG ADULT;

ADOLESCENT; ADULT; BIOPSY; COMPUTER SIMULATION; FEMALE; HUMANS; IRON; IRON OVERLOAD; LIVER; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; YOUNG ADULT;

EID: 84930930574     PISSN: 0730725X     EISSN: 18735894     Source Type: Journal    
DOI: 10.1016/j.mri.2015.02.016     Document Type: Article

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