Peto’s paradox and the hallmarks of cancer: Constructing an evolutionary framework for understanding the incidence of cancer

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 370, Issue 1673, 2015, Pages

  Nunney, L ^a   Muir, B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cancer; Evolution; Hallmarks; Multistage carcinogenesis; Mutation selection balance; Peto s paradox

Indexed keywords

BODY SIZE; CANCER; CARCINOGEN; DEFENSE MECHANISM; EVOLUTIONARY BIOLOGY; GENETIC ANALYSIS; HEALTH RISK; LITERATURE REVIEW; LONGEVITY; MUTATION; OBSERVATIONAL METHOD;

ANIMAL; BIOLOGICAL MODEL; BODY SIZE; CELL PROLIFERATION; EVOLUTION; GENETICS; HUMAN; LONGEVITY; MUTATION; NEOPLASMS; PATHOLOGY; RISK FACTOR; STEM CELL;

ANIMALS; BIOLOGICAL EVOLUTION; BODY SIZE; CELL PROLIFERATION; HUMANS; LONGEVITY; MODELS, BIOLOGICAL; MUTATION; NEOPLASMS; RISK FACTORS; STEM CELLS;

EID: 84930923312     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2015.0161     Document Type: Article

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