The Epidemiology of Staphylococcus aureus Transmission in the Anesthesia Work Area

Anesthesia and Analgesia

Volumn 120, Issue 4, 2015, Pages 807-818

  Loftus, Randy W ^a   Koff, Matthew D ^a   Brown, Jeremiah R ^b   Patel, Hetal M ^a   Jensen, Jens T ^a   Reddy, Sundara ^c   Ruoff, Kathryn L ^a   Heard, Stephen O ^d   Yeager, Mark P ^a   Dodds, Thomas M ^a  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^b DARTMOUTH INSTITUTE FOR HEALTH POLICY AND CLINICAL PRACTICE   (United States)

^c UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; CEFAZOLIN; CEFEPIME; CEFTAZIDIME; CEFUROXIME; CIPROFLOXACIN; CLINDAMYCIN; COTRIMOXAZOLE; LINEZOLID; MEROPENEM; METICILLIN; PENICILLIN DERIVATIVE; TAZOBACTAM; ANTIINFECTIVE AGENT;

ADOLESCENT; ANESTHESIA; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL TRANSMISSION; BACTERIUM CONTAMINATION; BACTERIUM CULTURE; BACTERIUM ISOLATION; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE ASSOCIATION; DISK DIFFUSION; ENVIRONMENTAL FACTOR; EPIDEMIOLOGICAL DATA; FEMALE; GROWTH RATE; HAND; HEALTHCARE ASSOCIATED INFECTION; HUMAN; INFECTION RISK; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MULTICENTER STUDY; NASOPHARYNX; PHENOTYPIC VARIATION; POSTOPERATIVE CARE; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; RISK FACTOR; SKIN SURFACE; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; WORK ENVIRONMENT; ADULT; ADVERSE EFFECTS; AGED; ANESTHESIOLOGY; CLINICAL TRIAL; CROSS INFECTION; DEVICES; DRUG EFFECTS; MEDICAL DEVICE CONTAMINATION; MICROBIAL SENSITIVITY TEST; MIDDLE AGED; OPERATING ROOM; PHENOTYPE; POSTOPERATIVE PERIOD; PROCEDURES; PROSPECTIVE STUDY; SKIN; STAPHYLOCOCCAL INFECTIONS; TIME; TRANSMISSION;

ADULT; AGED; ANESTHESIA; ANESTHESIOLOGY; ANTI-BACTERIAL AGENTS; CROSS INFECTION; DRUG RESISTANCE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; EQUIPMENT CONTAMINATION; FEMALE; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; OPERATING ROOMS; PHENOTYPE; POSTOPERATIVE PERIOD; PROSPECTIVE STUDIES; RISK FACTORS; SKIN; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TIME FACTORS;

EID: 84930896837     PISSN: 00032999     EISSN: 15267598     Source Type: Journal    
DOI: 10.1213/ANE.0b013e3182a8c16a     Document Type: Article

References (27)

1. National Nosocomial Infections Surveillance System. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control 2004;32:470-85
2. Klevens RM, Morrison MA, Nadle J, Petit S, Gershman K, Ray S, Harrison LH, Lynfield R, Dumyati G, Townes JM, Craig AS, Zell ER, Fosheim GE, McDougal LK, Carey RB, Fridkin SK. Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA 2007;298:1763-71
3. Department of Health and Human Services and Centers for Medicare & Medicaid Services. Medicare Program; Proposed Changes to the Hospital Inpatient Prospective Payment Systems and Fiscal Year 2008 Rates; Proposed Rule Part II. 42 CFR Parts 411, 412, 413, and 489 [CMS-1533-P] RIN 0938-A070. Fed Regist 2008;72:38-48
4. Dellinger E, Gordon S. Surgical-Associated Infection in Today's Operating Room. Special Report, Anesthesiology, General Surgery, and OB/GYN News. New York, NY: McMahon Publishing Group, 2006:1-10
5. Kirkland KB, Briggs JP, Trivette SL, Wilkinson WE, Sexton DJ. The impact of surgical-site infections in the 1990s: Attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol 1999;20:725-30
6. Loftus RW, Koff MD, Burchman CC, Schwartzman JD, Thorum V, Read ME, Wood TA, Beach ML. Transmission of pathogenic bacterial organisms in the anesthesia work area. Anesthesiology 2008;109:399-407
7. Loftus RW, Muffly MK, Brown JR, Beach ML, Koff MD, Corwin HL, Surgenor SD, Kirkland KB, Yeager MP. Hand contamination of anesthesia providers is an important risk factor for intraoperative bacterial transmission. Anesth Analg 2011;112:98-105
8. Koff MD, Loftus RW, Burchman CC, Schwartzman JD, Read ME, Henry ES, Beach ML. Reduction in intraoperative bacterial contamination of peripheral intravenous tubing through the use of a novel device. Anesthesiology 2009;110:978-85
9. Loftus RW, Brown JR, Koff MD, Reddy S, Heard SO, Patel HM, Fernandez PG, Beach ML, Corwin HL, Jensen JT, Kispert D, Huysman B, Dodds TM, Ruoff KL, Yeager MP. Multiple reservoirs contribute to intraoperative bacterial transmission. Anesth Analg 2012;114:1236-48
10. Vogel TR, Dombrovskiy VY, Lowry SF. Impact of infectious complications after elective surgery on hospital readmission and late deaths in the U.S. Medicare population. Surg Infect (Larchmt) 2012;13:307-11
11. Konvalinka A, Errett L, Fong IW. Impact of treating Staphylococcus aureus nasal carriers on wound infections in cardiac surgery. J Hosp Infect 2006;64:162-8
12. von Eiff C, Becker K, Machka K, Stammer H, Peters G. Nasal carriage as a source of Staphylococcus aureus bacteremia. Study Group. N Engl J Med 2001;344:11-6
13. Bode LG, Kluytmans JA, Wertheim HF, Bogaers D, Vandenbroucke-Grauls CM, Roosendaal R, Troelstra A, Box AT, Voss A, van der Tweel I, van Belkum A, Verbrugh HA, Vos MC. Preventing surgical-site infections in nasal carriers of Staphylococcus aureus. N Engl J Med 2010;362:9-17
14. Haley RW, Quade D, Freeman HE, Bennett JV; CDC SENIC Planning Committee. Study on the efficacy of nosocomial infection control (SENIC project): summary of study design. Am J Epidemiol 1980;111:472-85
15. Archibald LK, Jarvis WR. Health care-associated infection outbreak investigations by the Centers for Disease Control and Prevention, 1946-2005. Am J Epidemiol 2011;174 (Suppl):S47-64
16. Clinical Laboratory Standards Institute. Performance Standards for Antimicrobial Disk Susceptibility Tests; Approved Standard-9th ed. CLSI document M2-A9. 26:1. Wayne, PA: Clinical Laboratory Standards Institute, 2006
17. Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, Swaminathan B. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995;33:2233-9
18. Pray L. Antibiotic resistance, mutation rates and MRSA. Nature Education 2008:1
19. Loftus RW, Patel HM, Huysman BC, Kispert DP, Koff MD, Gallagher JD, Jensen JT, Rowlands J, Reddy S, Dodds TM, Yeager MP, Ruoff KL, Surgenor SD, Brown JR. Prevention of intravenous bacterial injection from health care provider hands: the importance of catheter design and handling. Anesth Analg 2012;115:1109-19
20. Bochner BR. Global phenotypic characterization of bacteria. FEMS Microbiol Rev 2009;33:191-205
21. Loftus RW, Brindeiro BS, Kispert DP, Koff MD, Jensen JT, Dodds TM, Yeager MP, Ruoff KL, Gallagher JD, Beach ML, Brown JR. Reduction in intraoperative bacterial contamination of peripheral intravenous tubing through the use of a passive catheter care station. Anesth Analg 2012;115:1315-23
22. Kluytmans JA, Mouton JW, VandenBergh MF, Manders MJ, Maat AP, Wagenvoort JH, Michel MF, Verbrugh HA. Reduction of surgical-site infections in cardiothoracic surgery by elimination of nasal carriage of Staphylococcus aureus. Infect Control Hosp Epidemiol 1996;17:780-5
23. Boyce JM, Pittet D; Healthcare Infection Control Practices Advisory Committee; HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. Guideline for hand hygiene in health-care settings. Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/ APIC/IDSA Hand Hygiene Task Force. Society for Healthcare Epidemiology of America/Association for Professionals in Infection Control/Infectious Diseases Society of America. MMWR Recomm Rep 2002;51:1-45
24. World Health Organization. WHO Guidelines on Hand Hygiene in Health Care (Advanced Draft). World Health Organization Health System Policies and Operations Evidence and Information for Policy. 9-13-0007. Geneva, Switzerland: World Health Organization, 2005
25. Webster J, Osborne S. Preoperative bathing or showering with skin antiseptics to prevent surgical site infection. Cochrane Database Syst Rev 2012;9:CD004985
26. Climo MW, Yokoe DS, Warren DK, Perl TM, Bolon M, Herwaldt LA, Weinstein RA, Sepkowitz KA, Jernigan JA, Sanogo K, Wong ES. Effect of daily chlorhexidine bathing on hospital-acquired infection. N Engl J Med 2013;368:533-42
27. Waters CM, Bassler BL. Quorum sensing: cell-to-cell communication in bacteria. Annu Rev Cell Dev Biol 2005;21:319-46