Multiparameter Analysis of Human Bone Marrow Stromal Cells Identifies Distinct Immunomodulatory and Differentiation-Competent Subtypes

Stem Cell Reports

Volumn 4, Issue 6, 2015, Pages 1004-1015

  James, Sally ^a   Fox, James ^a   Afsari, Farinaz ^a   Lee, Jennifer ^a   Clough, Sally ^a   Knight, Charlotte ^a   Ashmore, James ^a   Ashton, Peter ^a   Preham, Olivier ^a   Hoogduijn, Martin ^b   Ponzoni, Raquel De Almeida Rocha ^a   Hancock, Y ^a   Coles, Mark ^a   Genever, Paul ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 7; MEMBRANE ANTIGEN; TELOMERASE REVERSE TRANSCRIPTASE; BST2 PROTEIN, HUMAN; CXCL12 PROTEIN, HUMAN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; IL7 PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; STROMAL CELL DERIVED FACTOR 1; TELOMERASE; TERT PROTEIN, HUMAN; TRANSCRIPTOME;

ANTIGEN EXPRESSION; ARTICLE; BONE MARROW STROMA CELL; CELL DIFFERENTIATION; CELL SUBPOPULATION; CLONAL CELL LINE; COLONY FORMING CELL; CYTOKINE PRODUCTION; GENE EXPRESSION PROFILING; GENE INTERACTION; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMORTALIZED CELL LINE; IMMUNOLOCALIZATION; IMMUNOMODULATION; LYMPHOPOIESIS; PHENOTYPE; PRIORITY JOURNAL; RAMAN SPECTROMETRY; STROMA CELL; BONE MARROW CELL; CELL CULTURE; CELL LINEAGE; CELL TRACKING; CLUSTER ANALYSIS; CYTOLOGY; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; PRINCIPAL COMPONENT ANALYSIS;

ANTIGENS, CD; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL LINEAGE; CELL TRACKING; CELLS, CULTURED; CHEMOKINE CXCL12; CLUSTER ANALYSIS; GPI-LINKED PROTEINS; HUMANS; INTERLEUKIN-7; MESENCHYMAL STROMAL CELLS; PHENOTYPE; PRINCIPAL COMPONENT ANALYSIS; SPECTRUM ANALYSIS, RAMAN; TELOMERASE; TRANSCRIPTOME;

EID: 84930894731     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2015.05.005     Document Type: Article

References (29)

1. R. Ceredig, and A.G. Rolink The key role of IL-7 in lymphopoiesis Semin. Immunol. 24 2012 159 164
2. J.W. Chan, D.S. Taylor, T. Zwerdling, S.M. Lane, K. Ihara, and T. Huser Micro-Raman spectroscopy detects individual neoplastic and normal hematopoietic cells Biophys. J. 90 2006 648 656
3. M.J. Crop, C.C. Baan, S.S. Korevaar, J.N. Ijzermans, M. Pescatori, A.P. Stubbs, W.F. van Ijcken, M.H. Dahlke, E. Eggenhofer, W. Weimar, and M.J. Hoogduijn Inflammatory conditions affect gene expression and function of human adipose tissue-derived mesenchymal stem cells Clin. Exp. Immunol. 162 2010 474 486
4. F. Dazzi, and M. Krampera Mesenchymal stem cells and autoimmune diseases Best Pract. Res. Clin. Haematol. 24 2011 49 57
5. M. Dominici, K. Le Blanc, I. Mueller, I. Slaper-Cortenbach, F. Marini, D. Krause, R. Deans, A. Keating, Dj. Prockop, E. Horwitz The International Society for Cellular Therapy Position Statement Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement Cytotherapy 8 2006 315 317
6. H. Dooms Interleukin-7: Fuel for the autoimmune attack J. Autoimmun. 45 2013 40 48
7. D. Hotter, D. Sauter, and F. Kirchhoff Emerging role of the host restriction factor tetherin in viral immune sensing J. Mol. Biol. 425 2013 4956 4964
8. K. Johnson, S. Zhu, M.S. Tremblay, J.N. Payette, J. Wang, L.C. Bouchez, S. Meeusen, A. Althage, C.Y. Cho, X. Wu, and P.G. Schultz A stem cell-based approach to cartilage repair Science 336 2012 717 721
9. S.A. Kuznetsov, P.H. Krebsbach, K. Satomura, J. Kerr, M. Riminucci, D. Benayahu, and P.G. Robey Single-colony derived strains of human marrow stromal fibroblasts form bone after transplantation in vivo J. Bone Miner. Res. 12 1997 1335 1347
10. K.H. Larsen, C.M. Frederiksen, J.S. Burns, B.M. Abdallah, and M. Kassem Identifying a molecular phenotype for bone marrow stromal cells with in vivo bone-forming capacity J. Bone Miner. Res. 25 2010 796 808
11. D. Long, S. Blake, X.Y. Song, M. Lark, and R.F. Loeser Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13 Arthritis Res. Ther. 10 2008 R23
12. Y. Mabuchi, S. Morikawa, S. Harada, K. Niibe, S. Suzuki, F. Renault-Mihara, D.D. Houlihan, C. Akazawa, H. Okano, and Y. Matsuzaki LNGFR(+)THY-1(+)VCAM-1(hi+) cells reveal functionally distinct subpopulations in mesenchymal stem cells Stem Cell Reports 1 2013 152 165
13. S. Méndez-Ferrer, T.V. Michurina, F. Ferraro, A.R. Mazloom, B.D. Macarthur, S.A. Lira, D.T. Scadden, A. Ma'ayan, G.N. Enikolopov, and P.S. Frenette Mesenchymal and haematopoietic stem cells form a unique bone marrow niche Nature 466 2010 829 834
14. Z. Movasaghi, S. Rehman, and I.U. Rehman Raman spectroscopy of biological tissues Appl. Spectrosc. Rev. 42 2007 493 541
15. A. Muraglia, R. Cancedda, and R. Quarto Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model J. Cell Sci. 113 2000 1161 1166
16. A.J. Nauta, and W.E. Fibbe Immunomodulatory properties of mesenchymal stromal cells Blood 110 2007 3499 3506
17. T. Okamoto, T. Aoyama, T. Nakayama, T. Nakamata, T. Hosaka, K. Nishijo, T. Nakamura, T. Kiyono, and J. Toguchida Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells Biochem. Biophys. Res. Commun. 295 2002 354 361
18. S. Pinho, J. Lacombe, M. Hanoun, T. Mizoguchi, I. Bruns, Y. Kunisaki, and P.S. Frenette PDGFRα and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion J. Exp. Med. 210 2013 1351 1367
19. M.F. Pittenger, A.M. Mackay, S.C. Beck, R.K. Jaiswal, R. Douglas, J.D. Mosca, M.A. Moorman, D.W. Simonetti, S. Craig, and D.R. Marshak Multilineage potential of adult human mesenchymal stem cells Science 284 1999 143 147
20. N. Quirici, D. Soligo, P. Bossolasco, F. Servida, C. Lumini, and G.L. Deliliers Isolation of bone marrow mesenchymal stem cells by anti-nerve growth factor receptor antibodies Exp. Hematol. 30 2002 783 791
21. P.G. Robey, S.A. Kuznetsov, M. Riminucci, and P. Bianco Bone marrow stromal cell assays: in vitro and in vivo Methods Mol. Biol. 1130 2014 279 293
22. K.C. Russell, D.G. Phinney, M.R. Lacey, B.L. Barrilleaux, K.E. Meyertholen, and K.C. O'Connor In vitro high-capacity assay to quantify the clonal heterogeneity in trilineage potential of mesenchymal stem cells reveals a complex hierarchy of lineage commitment Stem Cells 28 2010 788 798
23. K.C. Russell, M.R. Lacey, J.K. Gilliam, H.A. Tucker, D.G. Phinney, and K.C. O'Connor Clonal analysis of the proliferation potential of human bone marrow mesenchymal stem cells as a function of potency Biotechnol. Bioeng. 108 2011 2716 2726
24. B. Sacchetti, A. Funari, S. Michienzi, S. Di Cesare, S. Piersanti, I. Saggio, E. Tagliafico, S. Ferrari, P.G. Robey, M. Riminucci, and P. Bianco Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment Cell 131 2007 324 336
25. H.G. Schulze, S.O. Konorov, N.J. Caron, J.M. Piret, M.W. Blades, and R.F. Turner Assessing differentiation status of human embryonic stem cells noninvasively using Raman microspectroscopy Anal. Chem. 82 2010 5020 5027
26. N. Serakinci, P. Guldberg, J.S. Burns, B. Abdallah, H. Schrodder, T. Jensen, and M. Kassem Adult human mesenchymal stem cell as a target for neoplastic transformation Oncogene 23 2004 5095 5098
27. P.J. Simmons, and B. Torok-Storb Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1 Blood 78 1991 55 62
28. B.O. Zhou, R. Yue, M.M. Murphy, J.G. Peyer, and S.J. Morrison Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow Cell Stem Cell 15 2014 154 168
29. J. Zhu, R. Garrett, Y. Jung, Y. Zhang, N. Kim, J. Wang, G.J. Joe, E. Hexner, Y. Choi, R.S. Taichman, and S.G. Emerson Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells Blood 109 2007 3706 3712