DRACO inhibits porcine reproductive and respiratory syndrome virus replication in vitro

Archives of Virology

Volumn 160, Issue 5, 2015, Pages 1239-1247

  Guo, Chunhe ^a   Chen, Luxi ^a   Mo, Delin ^a   Chen, Yaosheng ^a   Liu, Xiaohong ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BIOLOGICAL PRODUCT; IMMUNOLOGIC FACTOR; OLIGOPEPTIDE;

ANIMAL; CELL CULTURE; DRUG EFFECTS; PHYSIOLOGY; PIG; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; BIOLOGICAL PRODUCTS; CELLS, CULTURED; IMMUNOLOGIC FACTORS; OLIGOPEPTIDES; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SWINE; VIRUS REPLICATION;

EID: 84930889108     PISSN: 03048608     EISSN: 14328798     Source Type: Journal    
DOI: 10.1007/s00705-015-2392-4     Document Type: Article

References (24)

1. Neumann EJ, Kliebenstein JB, Johnson CD, Mabry JW, Bush EJ, Seitzinger AH, Green AL, Zimmerman JJ (2005) Assessment of the economic impact of porcine reproductive and respiratory syndrome on swine production in the United States. J Am Vet Med A 227(3):385–392. doi:10.2460/javma.2005.227.385
2. Murtaugh MP, Genzow M (2011) Immunological solutions for treatment and prevention of porcine reproductive and respiratory syndrome (PRRS). Vaccine 29(46):8192–8204. doi:10.1016/j.vaccine.2011.09.013
3. Bosch AA, Biesbroek G, Trzcinski K, Sanders EA, Bogaert D (2013) Viral and bacterial interactions in the upper respiratory tract. Plos Pathog 9(1):e1003057. doi:10.1371/journal.ppat.1003057
4. Holtkamp D, Kliebenstein J (2011) Pork Checkoff study: PRRS costs industry $664 million annually. J Swine Health Prod 19(6):349
5. Music N, Gagnon CA (2010) The role of porcine reproductive and respiratory syndrome (PRRS) virus structural and non-structural proteins in virus pathogenesis. Anim Health Res Rev 11(2):135–163. doi:10.1017/S1466252310000034
6. Yun SI, Lee YM (2013) Overview: replication of porcine reproductive and respiratory syndrome virus. J Microbiol 51(6):711–723. doi:10.1007/s12275-013-3431-z
7. Tian K, Yu X, Zhao T, Feng Y, Cao Z, Wang C, Hu Y, Chen X, Hu D, Tian X, Liu D, Zhang S, Deng X, Ding Y, Yang L, Zhang Y, Xiao H, Qiao M, Wang B, Hou L, Wang X, Yang X, Kang L, Sun M, Jin P, Wang S, Kitamura Y, Yan J, Gao GF (2007) Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallmark. PloS One 2(6):e526. doi:10.1371/journal.pone.0000526
8. Murtaugh MP, Xiao Z, Zuckermann F (2002) Immunological responses of swine to porcine reproductive and respiratory syndrome virus infection. Viral Immunol 15(4):533–547. doi:10.1089/088282402320914485
9. Labarque GG, Nauwynck HJ, Van Reeth K, Pensaert MB (2000) Effect of cellular changes and onset of humoral immunity on the replication of porcine reproductive and respiratory syndrome virus in the lungs of pigs. J Gen Virol 81(Pt 5):1327–1334
10. Xiao Z, Batista L, Dee S, Halbur P, Murtaugh MP (2004) The level of virus-specific T-cell and macrophage recruitment in porcine reproductive and respiratory syndrome virus infection in pigs is independent of virus load. J Virol 78(11):5923–5933. doi:10.1128/JVI.78.11.5923-5933.2004
11. Rider TH, Zook CE, Boettcher TL, Wick ST, Pancoast JS, Zusman BD (2011) Broad-spectrum antiviral therapeutics. PloS One 6(7):e22572. doi:10.1371/journal.pone.0022572
12. Samuel CE (2004) Knockdown by RNAi-proceed with caution. Nat Biotechnol 22(3):280–282. doi:10.1038/nbt0304-280
13. Qiao SL, Feng LL, Bao DK, Guo JQ, Wan B, Xiao ZJ, Yang SZ, Zhang GP (2011) Porcine reproductive and respiratory syndrome virus and bacterial endotoxin act in synergy to amplify the inflammatory response of infected macrophages. Vet Microbiol 149(1–2):213–220. doi:10.1016/j.vetmic.2010.11.006
14. Sadler AJ, Williams BRG (2007) Structure and function of the protein kinase R. Curr Top Microbiol Immunol 316:253–292
15. Ho A, Schwarze SR, Mermelstein SJ, Waksman G, Dowdy SF (2001) Synthetic protein transduction domains: Enhanced transduction potential in vitro and in vivo. Cancer Res 61(2):474–477
16. Delogu I, Pastorino B, Baronti C, Nougairede A, Bonnet E, de Lamballerie X (2011) In vitro antiviral activity of arbidol against Chikungunya virus and characteristics of a selected resistant mutant. Antivir Res 90(3):99–107. doi:10.1016/j.antiviral.2011.03.182
17. Costers S, Lefebvre DJ, Delputte PL, Nauwynck HJ (2008) Porcine reproductive and respiratory syndrome virus modulates apoptosis during replication in alveolar macrophages. Arch Virol 153(8):1453–1465. doi:10.1007/s00705-008-0135-5
18. Fensterl V, Sen GC (2011) The ISG56/IFIT1 gene family. J Interf Cytokine Res 31(1):71–78. doi:10.1089/jir.2010.0101
19. Miettinen JJ, Matikainen S, Nyman TA (2012) Global secretome characterization of herpes simplex virus 1-infected human primary macrophages. J Virol 86(23):12770–12778. doi:10.1128/JVI.01545-12
20. Meulenberg JJ (2000) PRRSV, the virus. Vet Res 31(1):11–21. doi:10.1051/vetres:2000103
21. Suarez P (2000) Ultrastructural pathogenesis of the PRRS virus. Vet Res 31(1):47–55. doi:10.1051/vetres:2000056
22. Jourdan SS, Osorio FA, Hiscox JA (2012) Biophysical characterisation of the nucleocapsid protein from a highly pathogenic porcine reproductive and respiratory syndrome virus strain. Biochem Biophys Res Commun 419(2):137–141. doi:10.1016/j.bbrc.2011.11.126
23. Dokland T (2010) The structural biology of PRRSV. Virus Res 154(1–2):86–97. doi:10.1016/j.virusres.2010.07.029
24. Zhang L, Liu J, Bai J, Du Y, Wang X, Liu X, Jiang P (2013) Poly(I:C) inhibits porcine reproductive and respiratory syndrome virus replication in MARC-145 cells via activation of IFIT3. Antivir Res 99(3):197–206. doi:10.1016/j.antiviral.2013.06.004