HIV testing during the neonatal period

Southern African Journal of HIV Medicine

Volumn 16, Issue 1, 2015, Pages

  Sherman, Gayle G ^a,b  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

NEVIRAPINE; VIRUS DNA; VIRUS RNA; ZIDOVUDINE;

ANTIVIRAL THERAPY; ARTIFICIAL MILK; DRUG USE; EARLY DIAGNOSIS; EARLY INTERVENTION; FALSE NEGATIVE RESULT; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HIV TEST; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTERPERSONAL COMMUNICATION; LIMIT OF DETECTION; LOW BIRTH WEIGHT; META ANALYSIS (TOPIC); MIXED INFECTION; NEWBORN; NEWBORN MORBIDITY; NEWBORN MORTALITY; NEWBORN PERIOD; NONHUMAN; POLYMERASE CHAIN REACTION; PRACTICE GUIDELINE; PREMATURITY; PROPHYLAXIS; PROTEIN BLOTTING; REVIEW; RISK FACTOR; SINGLE DRUG DOSE; TREATMENT DURATION; TUBERCULOSIS; VERTICAL TRANSMISSION; VIRAL LOAD TESTING; VIRUS DETECTION; VIRUS LOAD; VIRUS TRANSMISSION;

EID: 84930838369     PISSN: 16089693     EISSN: 20786751     Source Type: Journal    
DOI: 10.4102/sajhivmed.v16i1.362     Document Type: Review

References (20)

1. National Department of Health. National consolidated guidelines for the prevention of mother-to-child transmission of HIV (PMTCT) and the management of HIV in children, adolescents and adults. Pretoria: Department of Health; 24 December 2014.
2. Bourne DE, Thompson M, Brody LL, et al. Emergence of a peak in early infant mortality due to HIV/AIDS in South Africa. AIDS. 2009;23:101-106. http://dx.doi.org/10.1097/QAD.0b013e32831c54bd.
3. Marston M, Becquet R, Zaba B, et al. Net survival of perinatally and postnatally HIV-infected children: A pooled analysis of individual data from sub-Saharan Africa. Int J Epidemiol. 2011;40:385-396. http://dx.doi.org/10.1093/ije/dyq255.
4. Lilian RR, Kalk E, Technau KG, Sherman GG. Birth diagnosis of HIV infection in infants to reduce infant mortality and monitor for elimination of mother-to-child transmission. Pediatr Infect Dis J. 2013;32:1080-1085. http://dx.doi.org/10.1097/INF.0b013e318290622e.
5. Mphatswe W, Blanckenberg N, Tudor-Williams G, et al. High frequency of rapid immunological progression in African infants infected in the era of perinatal HIV prophylaxis. AIDS. 2007;21:1253-1261. http://dx.doi.org/10.1097/QAD.0b013e3281a3bec2.
6. Lilian RR. Identifying interventions to improve outcomes of the South African Prevention of Mother-to-Child Transmission Programme. Dissertation for MScMed, Faculty of Health Sciences, University of the Witwatersrand; 2013.
7. Shapiro DE, Balasubramanian R, Fowler MG, et al. Time to HIV DNA-PCR positivity according to maternal/infant antiretroviral prophylactic regimen in non-breastfed HIV-infected infants in populations with predominantly non-B HIV subtype: A collaborative analysis of data from cohorts in Thailand, South Africa, Botswana and the United Kingdom [TUAB0203]. Presented at: 6th IAS conference on HIV pathogenesis, treatment and prevention. Rome, Italy: 17-20 July 2011.
8. Burgard M, Blanche S, Jasseron C, et al. Performance of HIV-1 DNA or HIV-1 RNA tests for early diagnosis of perinatal HIV-1 infection during anti-retroviral prophylaxis. J Pediatr. 2012;160:60-66.e1.
9. Nielsen-Saines K, Watts DH, Veloso VG, et al. Three postpartum antiretroviral regimens to prevent intrapartum HIV infection. N Engl J Med. 2012;366:2368- 2379. http://dx.doi.org/10.1056/NEJMoa1108275.
10. Mitchell C, Dross S, Beck IA, Micek MA, Frenkel LM. Low concentrations of HIV-1 DNA at birth delays diagnosis, complicating identification of infants for antiretroviral therapy to potentially prevent the establishment of viral reservoirs. Clin Infect Dis. 2014;58:1190-1193. http://dx.doi.org/10.1093/cid/ciu068.
11. Haeri Mazenderani AF, Du Plessis NM, Thomas WN, Venter E, Avenant T. Loss of detectability and indeterminate results: Challenges facing HIV infant diagnosis in South Africa's expanding ART programme. S Afr Med J. 2014;104:574-577. http://dx.doi.org/10.7196/samj.8322.
12. Connolly MD, Rutstein RM, Lowenthal ED. Virologic testing in infants with perinatal exposure to HIV receiving multidrug prophylaxis. Pediatr Infect Dis J. 2013;32:e54-e61. http://dx.doi.org/10.1097/INF.0b013e3182787c29.
13. Violari A, Cotton MF, Gibb DM, et al. Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med. 2008;359:2233-2244. http://dx.doi.org/10.1056/NEJMoa0800971.
14. Dunn DT, Brandt CD, Krivine A, et al. The sensitivity of HIV-1 DNA polymerase chain reaction in the neonatal period and the relative contributions of intra-uterine and intra-partum transmission. AIDS. 1995;9:F7-11. http://dx.doi.org/10.1097/00002030-199509000-00001.
15. Lilian RR, Kalk E, Bhowan K, et al. Early diagnosis of in utero and intrapartum HIV infection in infants prior to 6 weeks of age. J Clin Microbiol. 2012;50:2373-2377. http://dx.doi.org/10.1128/JCM.00431-12.
16. Lilian RR, Johnson LF, Moolla H, Sherman GG. A mathematical model evaluating the timing of early diagnostic testing in HIV-exposed infants in South Africa. J Acquir Immune Def Syndr. 2014;67:341-348. http://dx.doi.org/10.1097/QAI.0000000000000307.
17. Department of Health. Western Cape PMTCT clinical guidelines. June 2014. Cape Town: Western Cape Government Department of Health; 2014.
18. World Health Organization. WHO recommendations on the diagnosis of HIV infection in infants and children. c2010 [cited 04 February 2015]. Available from: http://www.who.int/hiv/pub/paediatric/diagnosis/en/.
19. Sherman GG, Lilian RR, Coovadia AH. The performance of 5 rapid HIV tests using whole blood in infants and children: Selecting a test to achieve the clinical objective. Pediatr Infect Dis J. 2012;31:267-272. http://dx.doi.org/10.1097/INF.0b013e31823752a0.
20. Panel on Antiretroviral Therapy and Medical Management of HIV-infected Children. Guidelines for the use of antiretroviral agents in pediatric HIV infection. c2014 [cited 29 July 2014]. Available from: http://aidsinfo.nih.gov/guidelines.