Vascular smooth muscle cell calcification is mediated by regulated exosome secretion

Circulation Research

Volumn 116, Issue 8, 2015, Pages 1312-1323

  Kapustin, Alexander N ^a   Chatrou, Martijn L L ^b   Drozdov, Ignat ^a   Zheng, Ying ^c   Davidson, Sean M ^c   Soong, Daniel ^a   Furmanik, Malgorzata ^a   Sanchis, Pilar ^a   De Rosales, Rafael Torres Martin ^d   Alvarez Hernandez, Daniel ^a   Shroff, Rukshana ^e   Yin, Xiaoke ^a   Muller, Karin ^f   Skepper, Jeremy N ^f   Mayr, Manuel ^a   Reutelingsperger, Chris P ^b   Chester, Adrian ^g   Bertazzo, Sergio ^h   Schurgers, Leon J ^b   Shanahan, Catherine M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^f Multi Imaging Centre   (United Kingdom)

^g Heart Science Centre   (United Kingdom)

^h IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Exosomes; Extracellular matrix; Vascular calcification

Indexed keywords

CALCIUM; CALCIUM BINDING PROTEIN; CD63 ANTIGEN; CD81 ANTIGEN; CD9 ANTIGEN; FETUIN A; PLATELET DERIVED GROWTH FACTOR BB; SCLEROPROTEIN; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELIN PHOSPHODIESTERASE 3; TETRASPANIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AHSG PROTEIN, HUMAN; CYTOKINE; SIGNAL PEPTIDE; SMPD3 PROTEIN, HUMAN;

ARTICLE; BIOGENESIS; BIOMINERALIZATION; BLOOD VESSEL CALCIFICATION; CELL COMPARTMENTALIZATION; CELL MIGRATION; CHEMICAL LABELING; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DIALYSIS; ENZYME INHIBITION; EXOCYTOSIS; EXOSOME; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MEMBRANE MICROPARTICLE; MOLECULAR BIOLOGY; MULTIVESICULAR BODY; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEOMICS; VASCULAR SMOOTH MUSCLE CELL; ADOLESCENT; ADULT; CASE CONTROL STUDY; CELL CULTURE; FEMALE; GENETIC TRANSFECTION; GENETICS; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; PROTEIN TRANSPORT; RNA INTERFERENCE; SECRETION (PROCESS); SECRETORY VESICLE; SMOOTH MUSCLE FIBER; TIME; VASCULAR SMOOTH MUSCLE; YOUNG ADULT;

ADOLESCENT; ADULT; ALPHA-2-HS-GLYCOPROTEIN; CALCIUM; CASE-CONTROL STUDIES; CELLS, CULTURED; CYTOKINES; EXOCYTOSIS; EXOSOMES; FEMALE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTEIN TRANSPORT; PROTEOMICS; RNA INTERFERENCE; SECRETORY VESICLES; SPHINGOMYELIN PHOSPHODIESTERASE; TETRASPANINS; TIME FACTORS; TRANSFECTION; VASCULAR CALCIFICATION; YOUNG ADULT;

EID: 84930803061     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.305012     Document Type: Article

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