Empty follicle syndrome prevalence and management in oocyte donors

Human Reproduction

Volumn 29, Issue 10, 2014, Pages 2221-2227

  Blazquez, Anna ^a   Guillén, Juan José ^a   Colomé, Clara ^a   Coll, Oriol ^a   Vassena, Rita ^a   Vernaeve, Valerie ^a,b  

^a Clinica EUGIN   (Spain)

^b Fundación Privada EUGIN   (Spain)

Author keywords

Empty follicle syndrome; GNRH antagonist; GNRHA triggering; Oocyte donation; OPU

Indexed keywords

CHORIONIC GONADOTROPIN; GONADORELIN AGONIST; HUMAN MENOPAUSAL GONADOTROPIN; RECOMBINANT FOLLITROPIN; GONADORELIN;

ADULT; ARTICLE; CONTROLLED STUDY; DONOR; EMBRYO TRANSFER; EMPTY FOLLICLE SYNDROME; FEMALE; FERTILIZATION; HORMONAL REGULATION; HUMAN; HUMAN CELL; HYPOPHYSIS; OOCYTE; OOCYTE DONATION; OOCYTE MATURATION; OVARY DISEASE; PREGNANCY; PREVALENCE; RETROSPECTIVE STUDY; AGONISTS; OVARIAN DISEASES; OVULATION INDUCTION; PROCEDURES; SYNDROME;

ADULT; CHORIONIC GONADOTROPIN; FEMALE; GONADOTROPIN-RELEASING HORMONE; HUMANS; OOCYTE DONATION; OVARIAN DISEASES; OVULATION INDUCTION; RETROSPECTIVE STUDIES; SYNDROME;

EID: 84930793640     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deu203     Document Type: Article

References (29)

1. Aktas M, Beckers NG, van Inzen WG, Verhoeff A, de Jong D. Oocytes in the empty follicle: a controversial syndrome. Fertil Steril 2005;84:1643-1648.
2. Baum M, Machtinger R, Yerushalmi GM, Maman E, Seidman DS, Dor J, Hourvitz A. Recurrence of empty follicle syndrome with stimulated IVF cycle. Gynecol Endocrinol 2012;28:293-295.
3. Beckers N, Macklon N, Eijkemans M, Ludwig M, Felberbaum R, Diedrich K, Loumaye E, Fauser B. Nonsupplemented luteal phase characteristics after the administration of recombinant human chorionic gonadotropin, recombinant luteinizing hormone, or gonadotropin-releasing hormone (GnRH) agonist to induce final oocyte maturation in in vitro fertilization patients after ovarian stimulation with recombinant follicle-stimulation hormone and GnRH. J Clin Endocrinol Metab 2003;88:4186-4192.
4. Beck-Fruchter R, Weiss A, Lavee M, Geslevich Y, Shalev E. Empty follicle syndrome: successful treatment in a recurrent case and review of the literature. Hum Reprod 2012;27:1357-1367.
5. Ben-Shlomo I, Schiff E, Levran D, Ben-Rafael Z, Mashiach S, Dor J. Failure of oocyte retrieval during in vitro fertilization: a sporadic event rather than a syndrome. Fertil Steril 1991;55:324-327.
6. Butler SA, Khanlian SA, Cole LA. Detection of early pregnancy forms of human chorionic gonadotropin by home pregnancy test devices. Clin Chem 2001;47:2131-2136.
7. Castillo JC, Garcia-Velasco J, Humaidan P. Empty follicle syndrome after GnRHa triggering versus hCG triggering in COS. J Assist Reprod Genet 2012;29:249-253.
8. Coskun S, Madan S, Bukhari I, Al-Hassan S, Al-Rejjal R, Awartani K. Poor prognosis in cycles following 'genuine' empty follicle syndrome. Eur J Obstet Gynecol Reprod Biol 2010;150:157-159.
9. Coulam CB, Bustillo M, Schulman JD. Empty follicle syndrome. Fertil Steril 1986;46:1153-1155.
10. Doyle JO, Attaman JA, Styer AK, Sabatini ME, Petrozza JC, Toth TL. Rescue human chorionic gonadotropin for false empty follicle syndrome: optimism for successful pregnancy outcome. Fertil Steril 2012;98:450-452.
11. Driscoll GL, Tyler JP, Hangan JT, Fisher PR, Birdsall MA, Knight DC. A prospective, randomized, controlled, double-blind, double-dummy comparison of recombinant and urinary HCG for inducing oocyte maturation and follicular luteinization in ovarian stimulation. Hum Reprod 2000;15:1305-1310.
12. Fauser B, de Jong D, Olivennes F, Wramsby H, Tay C, Itskovitz-Eldor J, van Hooren H. Endocrine profiles after triggering of final oocyte maturation with GnRH agonist after cotreatment with the GnRH antagonist Ganirelix during ovarian hyperstimulation for in vitro fertilization. J Clin Endocrinol Metab 2002;87:709-715.
13. Hassan HA, Saleh HA, Khalil O, Baghdady I, Ismaiel I. Double oocyte aspiration may be a solution for empty follicle syndrome: case report. Fertil Steril 1998;69:138-139.
14. Inan MS, Al-Hassan S, Ozand P, Coskun S. Transcriptional profiling of granulosa cells from a patient with recurrent empty follicle syndrome. Reprod Biomed Online 2006;13:481-491.
15. Itskovitz-Eldor J, Kol S, Mannaerts B. Use of a single bolus of GnRHa triptorelin to trigger ovulation after GnRHan ganirelix treatment in women undergoing ovarian stimulation for assisted reproduction, with special reference to the prevention of ovarian hyperstimulation syndrome: preliminary report: short communication. Hum Reprod 2000;15:1965-1968.
16. Kim JH, Jee BC. Empty follicle syndrome. Clin Exp Reprod Med 2012;39:132-137.
17. Kummer NE, Feinn RS, Griffin DW, Nulsen JC, Benadiva CA, Engmann LL. Predicting successful induction of oocyte maturation after gonadotropinreleasing hormone agonist (GnRHa) trigger. Hum Reprod 2013;28:152-159.
18. Mesen TB, Yu B, Richter KS, Widra E, DeCherney AH, Segars JH. The prevalence of genuine empty follicle syndrome. Fertil Steril 2011;96:1375-1377.
19. Ndukwe G, Thornton S, Fishel S, Dowell K, Aloum M, Green S. 'Curing' empty follicle syndrome. Hum Reprod 1997;12:21-23.
20. Quintans CJ, Donaldson MJ, Blanco LA, Pasqualini RS. Empty follicle syndrome due to human errors: its occurrence in an in vitro fertilization programme. Hum Reprod 1998;13:2703-2705.
21. Reichman DE, Hornstein MD, Jackson KV, Racowsky C. Empty follicle syndrome-does repeat administration of hCG really work? Fertil Steril 2010;94:375-377.
22. Reichman DE, Greenwood E, Meyer L, Kligman I, Rosenwaks Z. Can in vitro fertilization cycles be salvaged by repeat administration of intramuscular human chorionic gonadotropin the day after failed injection? Fertil Steril 2012;98:671-674.
23. Stevenson TL, Lashen H. sEmpty follicle syndrome: the realityof acontroversial syndrome, a systematic review. Fertil Steril 2008;90:691-698.
24. Tsuiki A, Rose BI, Hung TT. Steroid profiles of follicular fluids from a patient with the empty follicle syndrome. Fertil Steril 1988;49:104-107.
25. van Heusden AM, van Santbrink EJ, Schipper I, de Jong D. The empty follicle syndrome is dead! Fertil Steril 2008;89:746.
26. Yariz KO, Walsh T, Uzak A, Spiliopoulos M, Duman D, Onalan G, King MC, Tekin M. Inherited mutation of the luteinizing hormone/choriogonadotropin receptor (LHCGR) in empty follicle syndrome. Fertil Steril 2011;96:e125-e130.
27. Younis JS, Skournik A, Radin O, Haddad S, Bar-Ami S, Ben-Ami M. Poor oocyte retrieval is a manifestation of low ovarian reserve. Fertil Steril 2005;83:504-507.
28. Zegers-Hochschild F, Fernandez E, Mackenna A, Fabres C, Altieri E, Lopez T. The empty follicle syndrome: a pharmaceutical industry syndrome. Hum Reprod 1995;10:2262-2265.
29. Zreik TG, Garcia-Velasco JA, Vergara TM, Arici A, Olive D, Jones EE. Empty follicle syndrome: evidence for recurrence. Hum Reprod 2000;15:999-1002.