Inhibition of miR-146b expression increases radioiodine-sensitivity in poorly differential thyroid carcinoma via positively regulating NIS expression

Biochemical and Biophysical Research Communications

Volumn 462, Issue 4, 2015, Pages 314-321

  Li, Luchuan ^a   Lv, Bin ^a   Chen, Bo ^a   Guan, Ming ^b   Sun, Yongfeng ^c   Li, Haipeng ^d   Zhang, Binbin ^a   Ding, Changyuan ^a   He, Shan ^a   Zeng, Qingdong ^a  

^a SHANDONG UNIVERSITY   (China)

^b Unit of Digestive Disease   (China)

^c Department of General Surgery Licheng District People's Hospital   (China)

^d Caoxian People's Hospital   (China)

Author keywords

Dedifferentiated thyroid carcinoma; Histone deacetylase; miR 146b; Na^{+< sup> I < sup> symporter; Radioiodine sensitivity}

Indexed keywords

HISTONE DEACETYLASE; HISTONE DEACETYLASE 3; IODINE 131; LUCIFERASE; MICRORNA; MICRORNA 146B; SODIUM IODIDE SYMPORTER; THYROID PEROXIDASE; UNCLASSIFIED DRUG; COTRANSPORTER; MIRN146 MICRORNA, HUMAN; PRIMER DNA; RADIOACTIVE IODINE;

APOPTOSIS; ARTICLE; BIOINFORMATICS; CANCER INHIBITION; CELL COUNT; CELL DEDIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG SENSITIVITY; DRUG UPTAKE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME REGULATION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INCUBATION TIME; POORLY DIFFERENTIATED THYROID CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THYROID CANCER CELL LINE; UPREGULATION; CELL DIFFERENTIATION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; THYROID TUMOR;

BASE SEQUENCE; CELL DIFFERENTIATION; DNA PRIMERS; HISTONE DEACETYLASES; HUMANS; IODINE RADIOISOTOPES; MICRORNAS; REAL-TIME POLYMERASE CHAIN REACTION; SYMPORTERS; THYROID NEOPLASMS;

EID: 84930757840     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.04.134     Document Type: Article

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