Is tuberculosis treatment really free in China? A study comparing two areas with different management models

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Qiu, Sangsang ^a   Pan, Hongqiu ^b   Zhang, Simin ^a   Peng, Xianzhen ^a   Zheng, Xianzhi ^a   Xu, Guisheng ^a   Wang, Min ^a   Wang, Jianming ^a,c   Lu, Hui ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Third Hospital of Zhenjiang City   (China)

^c Innovation Center for Social Risk Governance in Health   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LIVER PROTECTIVE AGENT; TUBERCULOSTATIC AGENT;

ADULT; AMBULATORY CARE; ARTICLE; CHINA; CONTROLLED STUDY; DESCRIPTIVE RESEARCH; DEVELOPED COUNTRY; ECONOMIC ASPECT; EDUCATION; FEMALE; HEALTH CARE COST; HEALTH CARE DELIVERY; HEALTH CARE POLICY; HEALTH INSURANCE; HOSPITALIZATION COST; HUMAN; INCOME; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; REIMBURSEMENT; SMEAR; SPUTUM ANALYSIS; THORAX RADIOGRAPHY; TUBERCULOSIS; TUBERCULOSIS CONTROL; UNSPECIFIED SIDE EFFECT; AGED; COMPARATIVE STUDY; COST OF ILLNESS; ECONOMICS; MIDDLE AGED; MULTIVARIATE ANALYSIS; STATISTICAL MODEL; THEORETICAL MODEL;

AGED; CHINA; COST OF ILLNESS; FEMALE; HEALTH EXPENDITURES; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; MODELS, THEORETICAL; MULTIVARIATE ANALYSIS; TUBERCULOSIS;

EID: 84930676989     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0126770     Document Type: Article

References (39)

1. WHO. Global tuberculosis report 2013: World Health Organization; 2013. Available: http://www.who.int/tb/publications/global-report/en/. Accessed 01 December 2014.
2. Falzon D, Mirzayev F, Wares F, Baena IG, Zignol M, Linh N, et al. Multidrug-resistant tuberculosis around the world: what progress has been made? Eur Respir J. 2015; 45:150-60. doi: 10.1183/09031936.00101814 PMID: 25261327.
3. Shao Y, Yang D, Xu W, Lu W, Song H, Dai Y, et al. Epidemiology of anti-tuberculosis drug resistance in a Chinese population: current situation and challenges ahead. BMC Public Health. 2011; 11:110. doi: 10.1186/1471-2458-11-110 PMID: 21324205.
4. Lutge E, Lewin S, Volmink J, Friedman I, Lombard C. Economic support to improve tuberculosis treatment outcomes in South Africa: a pragmatic cluster-randomized controlled trial. Trials. 2013; 14:154. doi: 10.1186/1745-6215-14-154 PMID: 23714270.
5. Gurung GN, Chhetri PS, Jha N. Economic impact of pulmonary tuberculosis on patients and their families of Dharan municipality, Nepal. Nepal Med Coll J. 2012; 14:196-8. PMID: 24047014.
6. Liefooghe R, Michiels N, Habib S, Moran MB, De Muynck A. Perception and social consequences of tuberculosis: a focus group study of tuberculosis patients in Sialkot, Pakistan. Soc Sci Med. 1995; 41:1685-92. PMID: 8746868.
7. Xu B, Dong HJ, Zhao Q, Bogg L. DOTS in China - removing barriers or moving barriers? Health Policy Plan. 2006; 21:365-72. doi: 10.1093/heapol/czl019 PMID: 16940302.
8. Wang L, Liu J, Chin DP. Progress in tuberculosis control and the evolving public-health system in China. Lancet. 2007; 369:691-6. doi: 10.1016/S0140-6736(07)60316-X PMID: 17321314.
9. Lv X, Tang S, Xia Y, Wang X, Yuan Y, Hu D, et al. Adverse reactions due to directly observed treatment strategy therapy in chinese tuberculosis patients: a prospective study. PLOS One. 2013; 8:e65037. doi: 10.1371/journal.pone.0065037 PMID: 23750225.
10. Pan HQ, Bele S, Feng Y, Qiu SS, Lu JQ, Tang SW, et al. Analysis of the economic burden of diagnosis and treatment of tuberculosis patients in rural China. Int J Tuberc Lung Dis. 2013; 17:1575-80. doi: 10.5588/ijtld.13.0144 PMID: 24200271.
11. Wei X, Chen J, Chen P, Newell JN, Li H, Sun C, et al. Barriers to TB care for rural-to-urban migrant TB patients in Shanghai: a qualitative study. Trop Med Int Health. 2009; 14:754-60. doi: 10.1111/j.1365-3156.2009.02286.x PMID: 19392747.
12. Liu Q, Smith H, Wang Y, Tang S, Wang Q, Garner P. Tuberculosis patient expenditure on drugs and tests in subsidised, public services in China: a descriptive study. Trop Med Int Health. 2010; 15:26-32. doi: 10.1111/j.1365-3156.2009.02427.x PMID: 19917035.
13. Wei X, Zou G, Yin J, Walley J, Zhang X, Li R, et al. Effective reimbursement rates of the rural health insurance among uncomplicated tuberculosis patients in China. Trop Med Int Health. 2015; 20:304-11. doi: 10.1111/tmi.12438 PMID: 25430477.
14. Jia Z, Cheng S, Wang L. Tuberculosis control in China: striving for sustainability. Lancet. 2012; 379:2149. doi: 10.1016/S0140-6736(12)60942-8 PMID: 22682462.
15. Liu X, Thomson R, Gong Y, Zhao F, Squire SB, Tolhurst R, et al. How affordable are tuberculosis diagnosis and treatment in rural China? An analysis from community and tuberculosis patient perspectives. Trop Med Int Health. 2007; 12:1464-71. doi: 10.1111/j.1365-3156.2007.01953.x PMID: 18076553.
16. Xu B, Fochsen G, Xiu Y, Thorson A, Kemp JR, Jiang QW. Perceptions and experiences of health care seeking and access to TB care - a qualitative study in rural Jiangsu Province, China. Health Policy. 2004; 69:139-49. doi: 10.1016/j.healthpol.2003.11.006 PMID: 15212861.
17. Xu W, Lu W, Zhou Y, Zhu L, Shen H, Wang J. Adherence to anti-tuberculosis treatment among pulmonary tuberculosis patients: a qualitative and quantitative study. BMC Health Serv Res. 2009; 9:169. doi: 10.1186/1472-6963-9-169 PMID: 19765290.
18. Small P. Why India should become a global leader in high-quality, affordable TB diagnostics. Indian J Med Res. 2012; 135:685-9. PMID: 22771602.
19. Zhan S, Wang L, Yin A, Blas E. Revenue-driven in TB control - three cases in China. Int J Health Plann Manage. 2004; 19 Suppl 1:S63-78. doi: 10.1002/hpm.778 PMID: 15686061.
20. Long Q, Smith H, Zhang T, Tang S, Garner P. Patient medical costs for tuberculosis treatment and impact on adherence in China: a systematic review. BMC Public Health. 2011; 11:393. doi: 10.1186/1471-2458-11-393 PMID: 21615930.
21. Wei X, Zou G, Walley J, Yin J, Lonnroth K, Uplekar M, et al. China tuberculosis policy at crucial crossroads: comparing the practice of different hospital and tuberculosis control collaboration models using survey data. PLOS One. 2014; 9:e90596. doi: 10.1371/journal.pone.0090596 PMID: 24621996.
22. Wei X, Zou G, Yin J, Walley J, Sun Q. Comparing patient care seeking pathways in three models of hospital and TB programme collaboration in China. BMC Infect Dis. 2013; 13:93. doi: 10.1186/1471-2334-13-93 PMID: 23425261.
23. Barter DM, Agboola SO, Murray MB, Barnighausen T. Tuberculosis and poverty: the contribution of patient costs in sub-Saharan Africa - a systematic review. BMC Public Health. 2012; 12:980. doi: 10.1186/1471-2458-12-980 PMID: 23150901.
24. Laokri S, Drabo MK, Weil O, Kafando B, Dembele SM, Dujardin B. Patients are paying too much for tuberculosis: a direct cost-burden evaluation in Burkina Faso. PLOS One. 2013; 8:e56752. doi: 10.1371/journal.pone.0056752 PMID: 23451079.
25. Yip WC, Hsiao WC, Chen W, Hu S, Ma J, Maynard A. Early appraisal of China's huge and complex health-care reforms. Lancet. 2012; 379:833-42. doi: 10.1016/S0140-6736(11)61880-1 PMID: 22386036.
26. Zhang T, Liu X, Bromley H, Tang S. Perceptions of tuberculosis and health seeking behaviour in rural Inner Mongolia, China. Health Policy. 2007; 81:155-65. doi: S0168-8510(05)00302-7 [pii] doi: 10.1016/j.healthpol.2005.12.009 PMID: 16806562.
27. Liu Y, Hsiao WC, Eggleston K. Equity in health and health care: the Chinese experience. Soc Sci Med. 1999; 49:1349-56. doi: S0277953699002075 [pii]. PMID: 10509825.
28. Zhang T, Tang S, Jun G, Whitehead M. Persistent problems of access to appropriate, affordable TB services in rural China: experiences of different socio-economic groups. BMC Public Health. 2007; 7:19. doi: 1471-2458-7-19 [pii] doi: 10.1186/1471-2458-7-19 PMID: 17288593.
29. Tobe RG, Xu L, Zhou C, Yuan Q, Geng H, Wang X. Factors affecting patient delay of diagnosis and completion of Direct Observation Therapy, Short-course (DOTS) among the migrant population in Shandong, China. Biosci Trends. 2013; 7:122-8. PMID: 23836035.
30. San Pedro A, Oliveira RM. [Tuberculosis and socioeconomic indicators: systematic review of the literature]. Rev Panam Salud Publica. 2013; 33:294-301. PMID: 23698179.
31. Sreeramareddy CT, Qin ZZ, Satyanarayana S, Subbaraman R, Pai M. Delays in diagnosis and treatment of pulmonary tuberculosis in India: a systematic review. Int J Tuberc Lung Dis. 2014; 18:255-66. doi: 10.5588/ijtld.13.0585 PMID: 24670558.
32. Li Y, Ehiri J, Tang S, Li D, Bian Y, Lin H, et al. Factors associated with patient, and diagnostic delays in Chinese TB patients: a systematic review and meta-analysis. BMC Med. 2013; 11:156. doi: 10.1186/1741-7015-11-156 PMID: 23819847.
33. Karasulu AL, Altin S, Dalar L, Sokucu SN, Ozkan P. Can hospitalization provide better compliance in smear positive tuberculosis patients? Tuberk Toraks. 2009; 57:277-81. PMID: 19787466.
34. Ho MJ. Perspectives on tuberculosis among traditional Chinese medical practitioners in New York City's Chinatown. Cult Med Psychiatry. 2006; 30:105-22. doi: 10.1007/s11013-006-9010-6 PMID: 16721672.
35. Liu Q, Garner P, Wang Y, Huang B, Smith H. Drugs and herbs given to prevent hepatotoxicity of tuberculosis therapy: systematic review of ingredients and evaluation studies. BMC Public Health. 2008; 8:365. doi: 10.1186/1471-2458-8-365 PMID: 18939987.
36. Xu B, Zhao Q, Hu Y, Shi Y, Wang W, Diwan VK. Experiences in anti-tuberculosis treatment in patients with multiple previous treatments and its impact on drug resistant tuberculosis epidemics. Glob Health Action. 2014; 7:24593. doi: 10.3402/gha.v7.24593 PMID: 25138531.
37. Kik SV, Olthof SP, de Vries JT, Menzies D, Kincler N, van Loenhout-Rooyakkers J, et al. Direct and indirect costs of tuberculosis among immigrant patients in the Netherlands. BMC Public Health. 2009; 9:283. doi: 10.1186/1471-2458-9-283 PMID: 19656370.
38. Raviglione M, Zumla A, Marais B, Horton R, Motsoaledi A. A sustainable agenda for tuberculosis control and research. Lancet. 2012; 379:1077-8. doi: 10.1016/S0140-6736(12)60373-0 PMID: 22444391.
39. Li Y, Ehiri J, Oren E, Hu D, Luo X, Liu Y, et al. Are we doing enough to stem the tide of acquired MDR-TB in countries with high TB burden? Results of a mixed method study in Chongqing, China. PLOS One. 2014; 9:e88330. doi: 10.1371/journal.pone.0088330 PMID: 24505476.