Description of leprosy classification at baseline among patients enrolled at the uniform multidrug therapy clinical trial for leprosy patients in Brazil

American Journal of Tropical Medicine and Hygiene

Volumn 92, Issue 6, 2015, Pages 1280-1284

  Moura, Rodrigo Scaliante ^a   Penna, Gerson Oliveira ^a,b   Vaz Cardoso, Ludimila Paula ^a   De Andrade Pontes, Maria Araci ^a,c   Cruz, Rossilene ^a,d   De Sá Gonçalves, Heitor ^a,c   Penna, Maria Lúcia Fernandes ^a,e   De Araújo Stefani, Mariane Martins ^a   Bührer Sékula, Samira ^a  

^a FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

^b UNIVERSITY OF BRASILIA   (Brazil)

^c Dermatology Outpatient Clinic   (Brazil)

^d Centro de Referência Nacional Alfredo da Matta FUAM   (Brazil)

^e FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; PHENOLIC GLYCOLIPID I; LEPROSTATIC AGENT;

ADOLESCENT; ADULT; AGED; ARTICLE; BACTERIAL LOAD; BRAZIL; CHILD; CLINICAL FEATURE; DISEASE CLASSIFICATION; FEMALE; GOLD STANDARD; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MULTIBACILLARY LEPROSY; MYCOBACTERIUM LEPRAE; NONHUMAN; PAUCIBACILLARY LEPROSY; RELAPSE; SKIN BIOPSY; SLIT SKIN SMEAR; SMEAR; BIOPSY; CLASSIFICATION; CROSS-SECTIONAL STUDY; LEPROSY; LEPROSY, MULTIBACILLARY; LEPROSY, PAUCIBACILLARY; MICROBIOLOGY; MIDDLE AGED; PATHOLOGY; SKIN; YOUNG ADULT;

BACTERIA (MICROORGANISMS);

ADOLESCENT; ADULT; AGED; BIOPSY; BRAZIL; CHILD; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; LEPROSTATIC AGENTS; LEPROSY; LEPROSY, MULTIBACILLARY; LEPROSY, PAUCIBACILLARY; MALE; MIDDLE AGED; SKIN; YOUNG ADULT;

EID: 84930609226     PISSN: 00029637     EISSN: 14761645     Source Type: Journal    
DOI: 10.4269/ajtmh.14-0049     Document Type: Article

References (15)

1. Ridley DS, Jopling WH, 1966. Classification of leprosy according to immunity. A five-group system. Int J Lepr Other Mycobact Dis 34:255-273.
2. WHO, 2012. WHO Expert Committee on Leprosy: Eighth Report. Geneva, Switzerland: WHO.
3. ILA, 2002. Report of the International Leprosy Association Technical Forum. Paris, France, February 22-28, 2002: the diagnosis and classification of leprosy. Int J Lepr Other Mycobact Dis 70(Suppl 1):S23-S31.
4. Penna GO, Pontes M A A, Cruz R, Goncalves HS, Penna M L F, Bührer-Sékula S, 2012. A clinical trial for uniform multidrug therapy for leprosy patients in Brazil: rationale and design. Mem Inst Oswaldo Cruz 107(Suppl 1):22-27.
5. Penna M L F, Buhrer-Sékula S, Pontes M A A, Cruz R, Gonçalves H D S, Penna GO, 2012. Primary results of clinical trial for uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): reactions frequency in multibacillary patients. Lepr Rev 83:308-319.
6. Moura RS, Calado KL, Oliveira ML, Bührer-Sékula S, 2008. Leprosy serology using PGL-I: a systematic review. Rev Soc Bras Med Trop 41(Suppl 2):11-18.
7. Oskam L, Slim E, Bührer-Sékula S, 2003. Serology: recent developments, strengths, limitations and prospects: a state of the art overview. Lepr Rev 74:196-205.
8. Parkash O, Kumar A, Pandey R, Nigam A, Girdhar BK, 2008. Performance of a lateral flow test for the detection of leprosy patients in India. J Med Microbiol 57:130-132.
9. Bobosha K, Tjon Kon Fat EM, Van Den Eeden S J F, Bekele Y, Van Der Ploeg-Van Schip JJ, De Dood CJ, Dijkman K, Franken K L MC, Wilson L, Aseffa A, Spencer JS, Ottenhoff T H M, Corstjens P L AM, Geluk A, 2014. Field-evaluation of a new lateral flow assay for detection of cellular and humoral immunity against Mycobacterium leprae. PLoS Negl Trop Dis 8:e2845.
10. Lockwood D N J, Nicholls P, Smith W C S, Das L, Barkataki P, Van Brakel W, Suneetha S, 2012. Comparing the clinical and histological diagnosis of leprosy and leprosy reactions in the INFIR cohort of Indian patients with multibacillary leprosy. PLoS Negl Trop Dis 6:e1702.
11. Kumar B, Dogra S, Kaur I, 2004. Epidemiological characteristics of leprosy reactions: 15 years experience from north India. Int J Lepr Other Mycobact Dis 72:125-133.
12. Baohong J, 2001. Does there exist a subgroup of MB patients at greater risk of relapse after MDT? Lepr Rev 72:3-7.
13. Bührer-Sékula S, Smits HL, Gussenhoven GC, Van Leeuwen J, Amador S, Fujiwara T, Klatser PR, Oskam L, 2003. Simple and fast lateral flow test for classification of leprosy patients and identification of contacts with high risk of developing leprosy. J Clin Microbiol 41:1991-1995.
14. Landis JR, Koch GG, 1977. The measurement of observer agreement for categorical data. Biometrics 33:159-174.
15. Penna M L F, Buhrer-Sékula S, Pontes M A A, Cruz R, Gonçalves HS, Penna GO, 2014. Results from the clinical trial of uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): decrease in bacteriological index. Lepr Rev 85:262-266.