Goblet cell carcinoid tumor, mixed goblet cell carcinoid-adenocarcinoma, and adenocarcinoma of the appendix: Comparison of clinicopathologic features and prognosis

Archives of Pathology and Laboratory Medicine

Volumn 139, Issue 6, 2015, Pages 782-790

  Taggart, Melissa W ^a   Abraham, Susan C ^a   Overman, Michael J ^a   Mansfield, Paul F ^a   Rashid, Asif ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUCIN;

ADENOCARCINOMA; ADULT; AGED; APPENDIX; CANCER STAGING; CARCINOID; COMPARATIVE STUDY; FEMALE; GOBLET CELL; HUMAN; KAPLAN MEIER METHOD; MALE; METABOLISM; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATHOLOGY; PROGNOSIS; VERY ELDERLY; YOUNG ADULT;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; APPENDIX; CARCINOID TUMOR; FEMALE; GOBLET CELLS; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MUCINS; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PROGNOSIS; YOUNG ADULT;

EID: 84930399929     PISSN: 00039985     EISSN: 15432165     Source Type: Journal    
DOI: 10.5858/arpa.2013-0047-OA     Document Type: Article

References (42)

1. Gagné F, Fortin P, Dufour V, Delage C. Tumors of the appendix associating histologic features of carcinoid and adenocarcinoma [in French]. Ann Anat Pathol (Paris). 1969;14(4):393-406.
2. Klein HZ. Mucinous carcinoid tumor of the vermiform appendix. Cancer. 1974;33(3):770-777.
3. Isaacson P. Crypt cell carcinoma of the appendix (so-called adenocarcinoid tumor). Am J Surg Pathol. 1981;5(3):213-224.
4. Watson PH, Alguacil-Garcia A. Mixed crypt cell carcinoma: a clinicopathological study of the so-called 'goblet cell carcinoid'. Virchows Arch A Pathol Anat Histopathol. 1987;412(2):175-182.
5. Warkel RL, Cooper PH, Helwig EB. Adenocarcinoid, a mucin-producing carcinoid tumor of the appendix: a study of 39 cases. Cancer. 1978;42(6):2781-2793.
6. Edmonds P, Merino MJ, LiVolsi VA, Duray PH. Adenocarcinoid (mucinous carcinoid) of the appendix. Gastroenterology. 1984;86(2):302-309.
7. Lewin K. Carcinoid tumors and the mixed (composite) glandular-endocrine cell carcinomas. Am J Surg Pathol. 1987;11(suppl 1):71-86.
8. Burke AP, Sobin LH, Federspiel BH, Shekitka KM, Helwig EB. Goblet cell carcinoids and related tumors of the vermiform appendix. Am J Clin Pathol. 1990; 94(1):27-35.
9. Kanthan R, Saxena A, Kanthan SC. Goblet cell carcinoids of the appendix: immunophenotype and ultrastructural study. Arch Pathol Lab Med. 2001;125(3):386-390.
10. Carr NJ, Sobin LH. Neuroendocrine tumors of the appendix. Semin Diagn Pathol. 2004; 21(2):108-119.
11. Kuroda N, Mizushima S, Guo L, et al. Goblet cell carcinoid of the appendix: Investigation of the expression of b-catenin and E-cadherin. Pathol Int. 2001;51(4):283-287.
12. Ramnani DM, Wistuba II, Behrens C, Gazdar AF, Sobin LH, Albores-Saavedra J. K-ras and p53 mutations in the pathogenesis of classical and goblet cell carcinoids of the appendix. Cancer. 1999;86(1):14-21.
13. Warner TF, Seo IS. Goblet cell carcinoid of appendix: ultrastructural features and histogenetic aspects. Cancer. 1979;44(5):1700-1706.
14. Toumpanakis C, Standish RA, Baishnab E, Winslet MC, Caplin ME. Goblet cell carcinoid tumors (adenocarcinoid) of the appendix. Dis Colon Rectum. 2007;50(3):315-322.
15. Albores-Saavedra J, Henson DE, Batich K. Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix. Am J Surg Pathol. 2009;33(8):1259-1260.
16. Chetty R, Klimstra DS, Henson DE, Albores-Saavedra J. Combined classical carcinoid and goblet cell carcinoid tumor: a new morphologic variant of carcinoid tumor of the appendix. Am J Surg Pathol. 2010;33(8):1163-1167.
17. Höfler H, Klöppel G, Heitz PU. Combined production of mucus, amines and peptides by goblet-cell carcinoids of the appendix and ileum. Pathol Res Pract. 1984;178(6):555-561.
18. Subbuswamy SG, Gibbs NM, Ross CF, Morson BC. Goblet cell carcinoid of the appendix. Cancer. 1974;34(2):338-344.
19. rd series, fascicle 32.
20. van Eeden S, Offerhaus GJ, Hart AA, et al. Goblet cell carcinoid of the appendix: a specific type of carcinoma. Histopathology. 2007;51(6):763-773.
21. Abt AB, Carter SL. Goblet cell carcinoid of the appendix: an ultrastructural and histochemical study. Arch Pathol Lab Med. 1976;100(6):301-306.
22. Alsaad KO, Serra S, Schmitt A, Perren A, Chetty R. Cytokeratins 7 and 20 immunoexpression profile in goblet cell and classical carcinoids of appendix. Endocr Pathol. 2007;18(1):16-22.
23. Horiuchi S, Endo T, Shimoji H, et al. Goblet cell carcinoid of the appendix endoscopically diagnosed and examined with p53 immunostaining. J Gastroenterol. 1998;33(4):582-587.
24. Park K, Blessing K, Kerr K, Chetty U, Gilmour H. Goblet cell carcinoid of the appendix. Gut. 1990;31(3):322-324.
25. Chen KT. Appendiceal adenocarcinoid with ovarian metastasis. Gynecol Oncol. 1990;38(2):286-288.
26. Pham TH, Wolff B, Abraham SC, Drelichman E. Surgical and chemotherapy treatment outcomes of goblet cell carcinoid: a tertiary cancer center experience. Ann Surg Oncol. 2006;13(3):370-376.
27. Byrn JC, Wang JL, Divino CM, Nguyen SQ, Warner RR. Management of goblet cell carcinoid. J Surg Oncol. 2006;94(5):396-402.
28. Li CC, Hirowaka M, Qian ZR, Xu B, Sano T. Expression of E-cadherin, β-catenin, and Ki-67 in goblet cell carcinoids of the appendix: an immunohistochemical study with clinical correlation. Endocr Pathol. 2002;13(1):47-58.
29. McGory ML, Maggard MA, Kang H, O'Connell JB, Ko CY. Malignancies of the appendix: beyond case series reports. Dis Colon Rectum. 2005;48(12):2264-2271.
30. McCusker ME, Coté TR, Clegg LX, Sobin LH. Primary malignant neoplasms of the appendix: a population-based study from the surveillance, epidemiology and end-results program, 1973-1998. Cancer. 2002;94(12):3307-3312.
31. Butler JA, Houshiar A, Lin F, Wilson SE. Goblet cell carcinoid of the appendix. Am J Surg. 1994;168(6):685-687.
32. Stancu M, Wu TT, Wallace C, Houlihan PS, Hamilton SR, Rashid A. Genetic alterations in goblet cell carcinoids of the vermiform appendix and comparison with gastrointestinal carcinoid tumors. Mod Pathol. 2003;16(12):1189-1198.
33. Carr NJ, McCarthy WF, Sobin LH. Epithelial noncarcinoid tumors and tumor-like lesions of the appendix: a clinicopathologic study of 184 patients with a multivariate analysis of prognostic factors. Cancer. 1995;75(3):757-768.
34. nd edition. Cancer. 1990;66(10):2162-2167.
35. Tang LH, Shia J, Soslow RA, et al. Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix. Am J Surg Pathol. 2008;32(10):1429-1443.
36. th ed. Lyon, France: IARC Press; 2010:122-125. World Health Organization Classification of Tumours; vol 3.
37. th ed. New York, NY: Springer-Verlag; 2010:133-141.
38. O'Donnell ME, Badger SA, Beattie GC, Carson J, Garstin WI. Malignant neoplasms of the appendix. Int J Colorectal Dis. 2007;22(10):1239-48.
39. Varisco B, McAlvin B, Dias J, Franga D. Adenocarcinoid of the appendix: is right hemicolectomy necessary?: a meta-analysis of retrospective chart reviews. Am Surg. 2004;70(7):593-599.
40. Mahteme H, Sugarbaker PH. Treatment of peritoneal carcinomatosis from adenocarcinoid of appendiceal origin. Br J Surg. 2004;91:1168-1173.
41. Lin BT, Gown AM. Mixed carcinoid and adenocarcinoma of the appendix: report of 4 cases with immunohistochemical studies and a review of the literature. Appl Immunohistochem Mol Morphol. 2004;12(3):271-276.
42. Bilen MA, Taggart MW, Fournier K, et al. Pathologic complete response in poorly differentiated adenocarcinomas of the appendix: a case series. Acta Oncol. 2013;52(5):1044-1046.