12-month blood pressure results of catheter-based renal artery denervation for resistant hypertension the SYMPLICITY HTN-3 trial

Journal of the American College of Cardiology

Volumn 65, Issue 13, 2015, Pages 1314-1321

  Bakris, George L ^a   Townsend, Raymond R ^b   Flack, John M ^c   Brar, Sandeep ^d   Cohen, Sidney A ^b,d   D'Agostino, Ralph ^e   Kandzari, David E ^f   Katzen, Barry T ^g   Leon, Martin B ^h   Mauri, Laura ⁱ   Negoita, Manuela ^d   O'Neill, William W ^j   Oparil, Suzanne ^k   Rocha Singh, Krishna ^l   Bhatt, Deepak L ⁱ  

^a UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c WAYNE STATE UNIVERSITY   (United States)

^d MEDTRONIC INC   (United States)

^e BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^f PIEDMONT HEART INSTITUTE   (United States)

^g BAPTIST CARDIAC AND VASCULAR INSTITUTE   (United States)

^h NEW YORK PRESBYTERIAN HOSPITAL   (United States)

ⁱ BRIGHAM AND WOMEN S HOSPITAL   (United States)

^j HENRY FORD HOSPITAL   (United States)

^k UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^l Prairie Heart Institute   (United States)

more..

Author keywords

Ambulatory blood pressure monitoring; Renal denervation; Resistant hypertension

Indexed keywords

ADRENERGIC RECEPTOR BLOCKING AGENT; ALDOSTERONE ANTAGONIST; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; RENIN INHIBITOR; VASODILATOR AGENT;

ADULT; ANAMNESIS; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE MONITORING; COMPUTER SYSTEM; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIASTOLIC BLOOD PRESSURE; DRUG EFFICACY; FEMALE; GLOMERULUS FILTRATION RATE; HEMODIALYSIS; HUMAN; KIDNEY DENERVATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIOFREQUENCY; RANDOMIZED CONTROLLED TRIAL; RESISTANT HYPERTENSION; SYSTOLIC BLOOD PRESSURE; AGED; BLOOD PRESSURE; CATHETERIZATION; CLINICAL TRIAL; CROSSOVER PROCEDURE; FOLLOW UP; HYPERTENSION; INNERVATION; KIDNEY ARTERY; MIDDLE AGED; PHYSIOLOGY; PROCEDURES; SYMPATHECTOMY; TREATMENT OUTCOME;

ADULT; AGED; BLOOD PRESSURE; BLOOD PRESSURE DETERMINATION; BLOOD PRESSURE MONITORING, AMBULATORY; CATHETERIZATION; CROSS-OVER STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RENAL ARTERY; SYMPATHECTOMY; TREATMENT OUTCOME;

EID: 84930344607     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2015.01.037     Document Type: Article

References (10)

1. Bhatt DL, Kandzari DE, O'Neill WW, et al. A controlled trial of renal denervation for resistant hypertension.New Engl JMed 2014;370:1393-401.
2. Bakris GL, Townsend RR, Liu M, et al. Impact of renal denervation on 24-hour ambulatory blood pressure: results from SYMPLICITY HTN-3. J Am Coll Cardiol 2014;64:1071-8.
3. Kandzari D, Bhatt D, Brar S, et al. Predictors of blood pressure response in the SYMPLICITY HTN-3 trial. Eur Heart J 2015;36:219-27.
4. Sakakura K, Ladich E, Cheng Q, et al. Anatomic assessment of sympathetic peri-arterial renal nerves in man. J Am Coll Cardiol 2014;64:635-43.
5. McCambridge J, Witton J, Elbourne DR. Systematic review of the Hawthorne effect: new concepts are needed to study research participation effects. J Clin Epidemiol 2014;67:267-77.
6. Castellano JM, Sanz G, Fernandez Ortiz A, Garrido E, Bansilal S, Fuster V. A polypill strategy to improve global secondary cardiovascular prevention: from concept to reality. J Am Coll Cardiol 2014;64:613-21.
7. Barnett AG, van der Pols JC, Dobson AJ. Regression to the mean: What it is and how to deal with it. Int J Epidemiol 2005;34:215-20.
8. Schmieder RE, Schmidt ST, Reimer T, et al. Disproportional decrease in office blood pressure compared with 24-hour ambulatory blood pressure with antihypertensive treatment. Hypertension 2014;64:1067-72.
9. Krum H, Schlaich MP, Sobotka PA, et al. Percutaneous renal denervation in patients with treatment-resistant hypertension: final 3-year report of the Symplicity HTN-1 study. Lancet 2014;383:622-9.
10. Desch S, Okon T, Heinemann D, et al. Symplicity flex: A prospective, randomized shamcontrolled trial of renal sympathetic denervation in mild refractory hypertension. Paper presented at: Transcatheter Cardiovascular Therapeutics 2014; September 16, 2014; Washington, DC.