Amelioration of radiation-induced hematopoietic syndrome by an antioxidant chlorophyllin through increased stem cell activity and modulation of hematopoiesis

Free Radical Biology and Medicine

Volumn 85, Issue , 2015, Pages 56-70

  Suryavanshi, Shweta ^a   Sharma, Deepak ^a   Checker, Rahul ^a   Thoh, Maikho ^a   Gota, Vikram ^b   Sandur, Santosh K ^a   Sainis, Krishna B ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

^b TATA MEMORIAL HOSPITAL   (India)

Author keywords

Hematopoiesis; Hematopoietic stem and progenitor cells; NF B; Nrf 2; Radioprotection

Indexed keywords

CHLOROPHYLL; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MANGANESE SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; ANTIOXIDANT; CHLOROPHYLLIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BONE MARROW; BONE MARROW APLASIA; BONE MARROW CELL; CELL ACTIVITY; CELL CYCLE ARREST; CELL LINEAGE; CELL SURVIVAL; CELL VIABILITY; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG HALF LIFE; GRANULOCYTE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MORTALITY; MOUSE; NEUTROPHIL; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; PROPHYLAXIS; RADIATION DOSE; RADIATION INDUCED HEMATOPOIETIC SYNDROME; RADIATION INJURY; RADIATION PROTECTION; SPLEEN; TREATMENT DURATION; UPREGULATION; WHOLE BODY RADIATION; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; RADIATION INJURIES; RADIATION RESPONSE;

MUS;

ANIMALS; ANTIOXIDANTS; CHLOROPHYLLIDES; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; MALE; MICE; MICE, INBRED BALB C; RADIATION INJURIES;

EID: 84930227031     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.04.007     Document Type: Article

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