Design and synthesis of novel N-arylsulfonyl-3-(2-yl-ethanone)-6-methylindole derivatives as inhibitors of HIV-1 replication

Pharmaceuticals

Volumn 8, Issue 2, 2015, Pages 221-229

  Che, Zhiping ^a   Liu, Shengming ^a   Tian, Yuee ^a   Hu, Zhenjie ^a   Chen, Yingwu ^a   Chen, Genqiang ^a  

^a HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Human immunodeficiency virus type 1; Inhibitor; N arylsulfonyl 3 (2 yl thanone) 6 methylindoles

Indexed keywords

INDOLE DERIVATIVE; N (4 ETHYL)PHENYLSULFONYL 3 (2 MORPHOLINOETHANONE) 6 METHYLINDOLE; N (4 ETHYL)PHENYLSULFONYL 3 ACETYL 6 METHYLINDOLE; N (4 ETHYL)PHENYLSULFONYL 3 [2 (5 PHENYL 1,3,4 OXADIAZOLE 2 YL THIO)ETHANONE] 6 METHYLINDOLE; N (4 ETHYL)PHENYLSULFONYL 3 [2 MORPHOLINOETHANONE] 6 METHYLINDOLE; N (4 ETHYL)PHENYLSULFONYL 6 METHYLINDOLE; N ARYLSULFONYL 3 (2 YL ETHANONE) 6 METHYLINDOLE DERIVATIVE; N PHENYLSULFONYL 3 (2 BUTYLAMINOETHANONE) 6 METHYLINDOLE; N PHENYLSULFONYL 3 (2 DIISOPROPYLAMINOETHANONE) 6 METHYLINDOLE; N PHENYLSULFONYL 3 (2 MORPHOLINOETHANONE) 6 METHYLINDOLE; N PHENYLSULFONYL 3 (2 PIPERIDINYLETHANONE) 6 METHYLINDOLE; N PHENYLSULFONYL 3 (2 PYRROLIDINOETHANONE) 6 METHYLINDOLE; N PHENYLSULFONYL 3 ACETYL 6 METHYLINDOLE; N PHENYLSULFONYL 3 [2 BUTYLAMINOETHANONE] 6 METHYLINDOLE; N PHENYLSULFONYL 3 [2 DIISOPROPYLAMINOETHANONE] 6 METHYLINDOLE; N PHENYLSULFONYL 3 [2 MORPHOLINOETHANONE] 6 METHYLINDOLE; N PHENYLSULFONYL 3 [2 PIPERIDINYLETHANONE] 6 METHYLINDOLE; N PHENYLSULFONYL 3 [2 PYRROLIDINOETHANONE] 6 METHYLINDOLE; N PHENYLSULFONYL 6 METHYLINDOLE; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CELL MEDIATED CYTOTOXICITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG DETERMINATION; DRUG SYNTHESIS; EC50; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; MTT ASSAY; NONHUMAN; STRUCTURE ACTIVITY RELATION; THERAPEUTIC EQUIVALENCE; VIRUS CELL INTERACTION; VIRUS REPLICATION;

EID: 84930202343     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph8020221     Document Type: Article

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